Didier Drogba scored his first Chelsea goal since his 2012 Champions League final strike as the Blues thrashed Maribor 6-0.
Manchester City surrendered a two-goal lead as they again stuttered in the Champions League, drawing 2-2 with CSKA Moscow.
A review of Tuesday night's action in the Sky Bet Championship at Derby went top after a 1-0 win at Blackpool.
Liverpool's Steven Gerrard admits the Champions League clash with Real Madrid should be regarded as a "bonus" match.
Arsene Wenger has every confidence Arsenal's rookie goalkeeper Emiliano Martinez will be up to the challenge on Wednesday.
Brendan Rodgers feels Gareth Bale's absence on Wednesday night is almost an irrelevance when Liverpool host Real Madrid.
Anderlecht manager Besnik Hasi maintains it would be a "mistake" to underestimate Arsenal on Wednesday night.
Real Madrid coach Carlo Ancelotti insists it is impossible for Cristiano Ronaldo to play better than he currently is.
MK Dons boss Karl Robinson has not been given permission to speak to Birmingham about their vacant manager's job.
UEFA could face questions after CSKA Moscow supporters appeared to gain entry to their side's clash with Manchester City.