Former England winger James Simpson-Daniel has announced his retirement because of an ankle injury.
Former Wales and Scarlets prop Rhys Thomas is undergoing surgery on Tuesday ahead of a heart transplant.
Australia coach Ewen McKenzie has made four changes to his side to face South Africa.
Northampton Saints have signed former London Irish flanker Jon Fisher ahead of the new Aviva Premiership campaign.
Pat Phibbs has returned to Exeter on a trial basis to ease the Aviva Premiership club's scrum-half injury spate.
Munster have confirmed the signing of Argentinian hooker Eusebio Guiñazú on a four-month contract.
Saracens have signed US Eagles hooker Phil Thiel as short-term cover for Schalk Brits, who is on South Africa duty.
Johnny Sexton faces a race against time to be fit for Ireland's autumn international Test series after breaking his jaw.
The Welsh Rugby Union and the four Regions have struck a deal which puts an end to their long-running dispute.
Jim Mallinder believes the IRB could let English clubs launch their domestic season after the 2015 World Cup pool stage.