The Power could win be set for a percentage boosting victory.
Season 2017 has panned out completely different for the two sides, with one of them set for a deep run into the finals and the other falling well short of the top eight.
Port Adelaide enter the round in the top four and will be keen to further push their claims with a big win while North Melbourne is a big chance for the wooden spoon.
North Melbourne has been a finals regular in recent years but now look set for a few seasons of pain as they rebuild their list.
Everything points to Port Adelaide winning and winning by a big margin!
North Melbourne has never won at the Adelaide Oval, losing all four matches, and they have not won a single game against the Power in South Australia since way back in 2011.
Port Adelaide come into this clash after upsetting the West Coast Eagles by 32 points. Star utility Ollie Wines was outstanding collecting 32 disposals and booting a goal over in the west.
North Melbourne is still a $10 chance in the ‘most losses’ market and could be worth a few sneaky dollars.
This looks an outstanding bet as they are just one game ahead of the Brisbane Lions and should both teams lose the same amount of games then the dead-heat rule will apply.
That means a bet on North will pay out at $5 as Brisbane will finish strongly and have home games against three of the competition strugglers Carlton, Gold Coast and the Western Bulldogs.
North Melbourne is unlikely to win another game this season and with each loss will blood youngsters but Port Adelaide on the other hand is going from strength to strength.
They are a great anchor for multi bets and you can back them with confidence at a variety of lines.
The Power are yet to beat a team in the top eight this season, but when they come up against the struggling sides they have too much class and once they get a sniff they become extremely confident.
Charlie Dixon kicked a game high five goals last week and looks a good bet to kick the most.
PORT ADELAIDE -36.5 LINE
NORTH MELBOURNE MOST LOSSES