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2022 Kentucky Derby Favorites: A Look at Zandon, Epicenter and the Rest of the Favorites

Kentucky Dery favorites ahead of Saturday's 2022 Kentucky Derby. Following yesterday's Kentucky Derby draw, we take a look at the 2022 Kentucky Derby favorites before Saturday's 148th running of the race at Churchill Downs.
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2022 Kentucky Derby Favorites: A Look at Zandon, Epicenter and the Rest of the Favorites

When odds are first released, everyone's eyes immediately navigate to the Kentucky Derby favorites.

Now, just because a horse is a Kentucky Derby favorite doesn't mean it's going to win, or even race well. However, favorites are the Kentucky Derby do have a history of coming to play under the sport's brightest lights.

I wouldn't go as far as to call this a two-horse race, anything can happen once the horses get to running, but there are two distinct 2022 Kentucky Derby favorites in Zandon and Epicenter. After those two, the horses become more closely grouped when it comes to their odds.

So, what exactly do the Kentucky Derby favorites, according to the latest odds, look like in 2022? Let's take a look at the odds for all horses and then break down the top-3 Kentucky Derby favorites this year.

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2022 Kentucky Derby Favorites - Kentucky Derby Odds

HorseKentucky Derby Odds
Mo Donegal10-1
White Abarrio10-1
Smile Happy20-1
Charge It20-1
Crown Pride20-1
Happy Jack30-1
Tiz The Bomb30-1
Barber Road30-1
Classic Causeway30-1
Ethereal Road30-1
Summer is Tomorrow30-1
Tawny Port30-1
Pioneer of Medina30-1

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2022 Kentucky Derby Favorites

1. Zandon (3-1)

When we're talking about Kentucky Dery favorites, it probably makes the most sense to start at the top. According to the latest Kentucky Derby odds, Zandon leads the pack when it comes to this year's Kentucky Derby Favorites.

Zandon as the top Kentucky Derby favorite is a bit of a shocker. Not to say he isn't a great horse, but it was long expected that we'd see Epicenter as the favorite, following consecutive graded stakes wins leading up to the Kentucky Derby.

However, it's Zandon, who is trained by Chad Brown, that will be the Morning Line favorite once betting opens for the 2022 Kentucky Derby on Saturday. Zandon will be racing from the No. 10 post.

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2. Epicenter (7-2)

As I mentioned above, Epicenter was expected by most to be the Kentucky Derby favorite, but he is the second favorite despite consecutive graded stakes wins, including the Louisianna Derby.

at 7-2, you still aren't getting fantastic odds on Epicenter, but they may only get worse, so now may be the time to pounce. Epicenter is trained by legendary trainer Steve Asmussen. Absent from this year's race is Bob Baffert, as he serves a two-year suspension from Churchill Downs.

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3. Messier (8-1)

Rounding out the top three Kentucky Derby favorites is Messier, sitting at 8-1 on the Morning Line for the 2022 Kentucky Derby.

Messier is trained by relative newcomer Tim Yakteen and will have jockey John R. Velazquez riding. With a lifetime line of 6-3-3-0, Messier has compiled $435,600 in earnings. At 8-1, he's more than double the price of the two Kentucky Derby favorites, Epicenter and Zandon.

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Brian is a sports journalist with close to ten years of experience in the business. A lifelong Philadelphia sports fan with a passion for all things sports gambling.


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