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The Kansas City Royals and Chicago White Sox play the middle game of a three-game series. Mike Spector breaks down the matchup.

Chicago White Sox vs. Kansas City Royals Prediction: Will the White Sox’s Losing Streak End Tonight?

Chicago White Sox vs. Kansas City Royals Start Time and Where to Watch

  • Date: April 27, 2022
  • Game Time: 2:10 pm ET
  • Where to Watch: MLB Extra Innings

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Chicago White Sox vs. Kansas City Royals Total Runs Movement

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Chicago White Sox vs. Kansas City Royals Prediction

The Chicago White Sox may have won the AL Central by 13 games last year, but the Kansas City Royals did not let the eventual champions walk all over them. The Royals went 10-9 against the White Sox last year, the only team in the division to go better than .500 against Chicago. 

Early indications are that this White Sox team will not cruise to a division title like last year. Chicago fell to 6-10 after last night’s 6-0 shutout loss to Kansas City and now find themselves amid an eight-game losing streak.

Is it time to panic on the South Side, or is this the day the White Sox end their ugly skid?

Read on for our best play in tonight's Royals-White Sox game.

Royals' starting pitcher Zack Greinke (0-1, 2.25) has been an anomaly in his first three starts. In today's era of baseball, while strikeouts have been increasing rapidly each year, Greinke has recorded just two strikeouts through 16 innings. Though more balls than usual are being put in play against Greinke, he has kept the ball in the yard, allowing no home runs to this point. 

What is worrisome about Greinke's outlook going forward is his 47.4% hard-hit percentage allowed is on pace to be by far the worst of his career (37.4% was his previous career-worst). He also has allowed a .281 BABIP, but his OPS allowed is on pace to be his best since 2015.

Greinke has faced Chicago just once since 2017, but the White Sox are one of five American League teams he is under .500 against in his career. Greinke is 9-10 in his career against Chicago but is 4-0 in his last four starts against them since 2010.

Opposing Greinke is Chicago's Dylan Cease (2-1, 3.38), who led the AL with 32 starts last season. Cease has allowed just one home run through 16 innings, a far cry from the 1.8 and 1.9 HR/9 averages from his first two Major League seasons. In addition, his 26.8% hard-hit percentage is on pace to be by far the lowest of his career after allowing 40.4%, 41.2%, and 38.8% in his first three seasons. 

Cease is 3-2 with a 2.96 ERA in nine career starts against Kansas City, and the Royals are just one of two teams (Tigers the other) against whom Cease has an ERA below 3.00 in at least three career starts. 

Greinke's inability to record easy outs via strikeouts will eventually catch up with him. We think it spells doom against a loaded White Sox lineup, albeit without Eloy Jimenez (hamstring). 

Kansas City has won five of its last six meetings against Chicago, but we look for the more talented White Sox squad to win tonight and cover the run line in the process.

Chicago White Sox vs. Kansas City Royals Prediction

PICK: White Sox -1.5 Runs (+125) (Bet $100 to win $125)

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Article Author


Mike Spector brings unmatched knowledge and insight into the game of football, and more importantly the process of betting on NFL football. Mike is the #2 ranked expert in FantasyPros' NFL betting contest


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