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The New York Mets host the St. Louis Cardinals tonight for the first game of a four-game series. Jason Radowitz breaks down the game.

New York Mets vs. St Louis Cardinals Prediction: Can the Cardinals Continue Their Offensive Explosion?

The New York Mets finally lost their first series of the season over the weekend. After two losses in their last three games, the Mets still have 23 wins to just 13 losses. Tonight, they'll take on a tough opponent in the St. Louis Cardinals. The Cardinals are 19-15 on the season and just went absolutely berzerk last night against the Giants offensively. We even got to see Albert Pujols pitch!

How will the Mets respond to losing their first series of the season? Here are our picks, predictions, and odds for Monday's game between the St. Louis Cardinals and New York Mets.

Get 40/1 odds on the Mets vs Cardinals Moneyline

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Mets vs. Cardinals Start Time, Where to Watch, and Odds

  • Date: May 16, 2022
  • Game Time: 7:10 pm ET
  • Where to Watch: SNY, BSMW

Mets vs. Cardinals Injury Report


Out: C James McCann (Wrist)


None of Importance

Mets vs. Cardinals Line Movement

New York Mets vs. St. Louis Cardinals Prediction

With Tylor Megill on the shelf, the Mets will start Trevor Williams for tonight's game. Williams has a 5.73 ERA to start the season along with a WHIP of 1.64. Pitchers like him are always dealt a tough hand. He's the guy who mops up bad pitching or gets the immediate start if a guy can't start. However, he had the best appearance in his last appearance. Against Washington, on May 11, he allowed no runs on two hits in 3.2 innings of work. Williams has struggled a bit against righties, however, allowing a .398 wOBA and ISO of .263 in his last 21 plate appearances against righties. The Cardinals will have a right-handed heavy lineup that has a .168 ISO and wOBA of .329 against righties. The Cardinals have limited strikeouts to 18.6% against righties in that same time frame. Meanwhile, Miles Mikolas has a 1.49 ERA on the season with a .94 WHIP to start the year for the Cardinals. Mikolas already went seven innings against the Mets in his first start against them, allowing no runs on four hits with five strikeouts. Mikolas also has a 3.96 xFIP in the last 30 days with just 4.1% of walks. Despite these numbers, the Cardinals find themselves as the underdogs in tonight's game.

The Mets only have a .123 ISO with a .318 wOBA against righties in the last 30 days. In the projected lineup, the Mets strike out 16.1% of the time against righties, however, the power numbers still lack. Take the Cardinals as the road underdog.

New York Mets vs. St. Louis Cardinals Pick

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Article Author


Jason grew up an avid sports fan. His passion for sports writing grew in high school and he developed a blog that was strictly for New York Sports. From his work, you will quickly realize that he loves looking at games from an analytical and numbers perspective and hopes to provide you with that same perspective in his articles.


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