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Tonight starts a short two-game series between the two teams in Chicago. The White Sox vs the Cubs. Which team will earn bragging rights as the winner of the first game? Jason Radowitz answers.

Chicago White Sox vs. Chicago Cubs Prediction: Which Chicago Team Will Earn Bragging Rights?

The Chicago Cubs didn't have many expectations coming into the season. At 18-26 on the season, the Cubs kind of expected this. Meanwhile, the Chicago White Sox are just 22-22 on the season after winning the AL Central last year. This was not expected but with an inconsistent offense, the White Sox are currently a .500 team. Can the White Sox build momentum against the Cubs and start to get past that .500 win mark?

Here are our picks, predictions, and odds for Saturday's game between the Chicago White Sox and the Chicago Cubs.

White Sox vs. Cubs Start Time, Where to Watch, and Odds

  • Date: May 28, 2022
  • Game Time: 7:15 pm ET
  • Where to Watch: FOX

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White Sox vs. Cubs Injury Report


Questionable: OF Seiya Suzuki (Finger)

Out: 2B David Bote (Shoulder), OF Clint Frazier (Illness), C Yan Gomes (Oblique)OF Michael Hermosillo (Quadriceps), OF Jason Heyward (Undisclosed), 2B Nick Madrigal (Back)

White Sox

Questionable: 3B Yoan Moncada (Leg) Out: OF Eloy Jimenez (Hamstring), OF Luis Robert (Illness)

Chicago White Sox vs. Chicago Cubs Prediction

It hasn’t been confirmed just yet, but it's more than likely going to be Keegan Thompson getting the start for the Chicago Cubs today. Thompson has a 4.96 xFIP in the last 30 days with just 19.2% of strikeouts. Against righties, Thompson has allowed a .345 wOBA and ISO of .267 in his last 34 plate appearances. Despite that, however, Thompson's limiting line drives and getting over 50% f ground balls in the last 30 days. The White Sox will have at least five righties in the lineup against Thompson, who has struggled to get righties out more this season. The offense has been inconsistent and still has a low ISO and wOBA number against righties. However, the matchup is still good enough that the White Sox can knock in some runs. Meanwhile, for the White Sox, it’ll be Johnny Cueto taking the mound. In two starts this season, Cueto has a 0.00 ERA with an xFIP of 3.88. It’s a small sample size for Cueto, as he’s pitched in two games, but overall, he’s looked really good through those 12 innings. Cueto is striking out 26.1% of batters and is limiting line drives while getting nearly 47% of ground balls.  The Cubs have a .170 ISO and wOBA of .296 against righties in the last 30 days. However, the Cubs are also striking out 27.8% of the time using their projected lineup against righties in the last 30 days. That should help Cueto keep things under control. It's going to come down to power for the Cubs. There is a lot of power in the Cubs’ lineup but so far, Cueto has kept those power numbers down. There won't be many runners on base going up against Cueto. Therefore, I'm going to take the White Sox, at home, with Cueto on the mound, at a solid price of -145.

Chicago White Sox vs. Chicago Cubs Pick

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Article Author


Jason grew up an avid sports fan. His passion for sports writing grew in high school and he developed a blog that was strictly for New York Sports. From his work, you will quickly realize that he loves looking at games from an analytical and numbers perspective and hopes to provide you with that same perspective in his articles.


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