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Louisville Cardinals vs. DePaul Blue Demons prediction and pick for Friday's college basketball matchup. Jason Radowitz gives his pick for tonight's showdown.

Louisville vs. DePaul Prediction: Is There Value on DePaul?

The DePaul Blue Demons will travel to the KFC Yum! Center to take on the Louisville Cardinals on the ACC Network. DePaul has just one loss on the season, and it came against a top 30 team in Loyola Chicago. It was a loss by just four points.

Meanwhile, Louisville is 6-2, with losses to Michigan State and Furman. However, the Cardinals also have wins against top-tier teams like Mississippi State, Maryland, and North Carolina State. This will be the Cardinals’ first game at home since November 20.

With the spread sitting at 7.5, is DePaul undervalued in this spot? Here are our picks and predictions for the Louisville vs. DePaul game for Friday, December 10.

Louisville vs. DePaul Start Time, Where to Watch, and Odds

Date: Friday, December 10, 2021Game Time: 8:00 pm ETWhere To Watch: ACCN

Click Here for Louisville vs. DePaul Odds

Louisville vs. DePaul INJURY REPORT

DePaul: Out: G Tyon Grant-Foster (Undisclosed)

Louisville: Out: G Mike James

Louisville vs. DePaul Prediction

The DePaul Blue Demons have been impressive this year. While Louisville has faced more challenging competition, on paper, in terms of analytics, DePaul is the better team.

The Blue Demons are shooting an effective field goal percentage of 54.9 percent while hitting 35.2 percent from downtown and 55.9 percent inside the arc. DePaul has also limited turnovers to 16.2 percent and has dominated the offensive glass with 35.2 percent offensive rebounds.

Despite all of that, Louisville can defend all of DePaul’s strengths. DePaul dominates inside, but Louisville holds opponents to 22.7 percent offensive rebounds and 42.8 percent shooting inside the arc on the season. The one area where DePaul could have more success in this game is getting to the line, but sometimes, on the road, it’s hard getting calls.

However, Louisville’s offense has not been up to par compared to the defense. The Cardinals are shooting an effective field goal percentage of 48.8 percent while turning the ball over 20.6 percent of the time. The Cardinals are only shooting 30.6 percent from downtown, and while they’re shooting 50.9 percent from inside the arc, DePaul has limited opponents to 43.5 percent inside the arc. As mentioned above, DePaul also gets to the line at a high rate, but they don’t foul at a high rate. Teams struggle to get to the line against DePaul’s defense.

Louisville will take more three-point shots in this game compared to DePaul. DePaul likes to work inside more frequently, and that’s been the reason for their success as they’ve shot 55.9 percent inside. Meanwhile, Louisville is stubborn and shoots from long range at a high rate while only hitting 30.6 percent of those shots. Against DePaul, however, Louisville should get some wide-open looks to capitalize on.

At the end of the day, Louisville is deeper. They’ve got a bench, whereas DePaul doesn’t. But DePaul has the athleticism and height that Louisville doesn’t necessarily match. I’m not ruling out a Louisville victory, but I think DePaul keeps this game close. I’ll take the points here.

Louisville Cardinals vs. DePaul Blue Demons Pick

Article Author


Jason grew up an avid sports fan. His passion for sports writing grew in high school and he developed a blog that was strictly for New York Sports. From his work, you will quickly realize that he loves looking at games from an analytical and numbers perspective and hopes to provide you with that same perspective in his articles.

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