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The Pittsburgh Panthers and the Xavier Musketeers kick off Sunday's March Madness slate. Which team will advance to the Sweet 16? Matt McCuen answers.

Xavier vs. Pittsburgh Prediction, Pick Against the Spread, and Latest Odds for Round of 32

The Pittsburgh Panthers and the Xavier Musketeers will clash in Greensboro, North Carolina, with an opportunity to reach the Sweet 16 on Sunday afternoon. This is a big game for us gamblers because it sets the mood for the day. It is always important to get action on the first game and to cash in.

Xavier vs. Pittsburgh Prediction

Xavier comes into this game on the heels of a come-from-behind win over Kennesaw State on Friday afternoon. Xavier trailed by double digits late in the second half, but they were able to lock in on the defensive end and get some key stops. This is a Xavier team that is poised to go on a run, and they are hopeful after that comeback, it can spark the team.

Pitt, meanwhile, is fresh off of a dominant win over Iowa State. We saw Pitt beat Missisp State in the forty-four games, and they followed that up with an even stronger performance vs. a good Iowa State team. The main reason for the Panther's success has been their defense.

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The Panthers held their opponents under sixty points in both games to start the tournament. They know that if they want to pull off the early upset today that they will have to score the basketball better than they did in the first couple of games facing this high-paced Xavier offense. Xavier enters play as a five-point favorite.

I am going to fade the public dog today and take the Musketeers. I think that a lot of people will overlook Xavier based on their lackluster performance against Kennesaw State. This is a new game, and that game is meaningless at this point.

On the flip side, I think the way Pitt has played in the first couple of games will catch up to them here. If Xavier can score the ball the way that they normally do, I believe that they can run away with this game today. Let’s start the day in the green! 

Xavier vs. Pittsburgh Pick

Pick: Xavier -5 (-110) Bet $100 to collect $190 Get the best odds at DraftKings; click here to bet

Xavier vs. Pittsburgh Start Time and Where to Watch

  • Date: March 19, 2023
  • Game Time: 12:10 pm ET
  • Arena: Greensboro Coliseum Complex
  • Where to Watch: CBS

Xavier vs. Pittsburgh Odds

  • Spread: Xavier -5 (-110) | Pittsburgh +5 (-109)
  • Total Odds: 151.5 (O (-110), U (-110)
  • Moneyline: Xavier (-200) | Pittsburgh (+185)

Click here for Xavier vs. Pittsburgh odds

Article Author


Matt McCuen is a native of Delco, PA. He has been working in the sports gambling industry and creating content for the last few years. He is an expert in numerous different sports, including the NFL, NBA, MLB, NHL, and collegiate sports. You can follow Matt on Twitter at @DeadPresPicks.


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