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College football returns this week starting with a Friday night slate, as UCF vs. Louisville takes us into a great weekend of college football. Johnny Covers breaks down this 3-leg parlay for NCAA's week 2 college football slate.

College Football Week 2 Parlay (+720): Cash In With This 3-Leg Plus Money Parlay

College football returns this week starting with a Friday night slate, as UCF vs. Louisville takes us into a great weekend of college football. While there are some marquee matchups throughout, let’s take a closer look at the four plays I see the most value in as opening kickoff quickly approaches. 

Week 2 College Football Parlay Predictions

All Odds via DraftKings

UCF -5 (-110)

Under the Friday Night Lights in Orlando, the ACC and AAC meet as Louisville attempts to earn their first victory of the year against a revamped Central Florida squad. The Cardinals' offense struggled in their season debut, a 31-7 loss to Syracuse, as quarterback Malik Cunningham threw for just 152 yards, no touchdowns, and two interceptions.

Ole Miss transfer John Rhys Plumlee made his Central Florida debut, throwing for 308 yards and four touchdowns in addition to rushing for 99 yards and another score. UCF did cover the large amount number while gaining some confidence, even though there isn't much to be gained materially from their 56-10 victory over South Carolina State.

Even still, with a massive edge at quarterback, I think UCF wins this one with relative ease. 

Houston ML (+125)

The Red Raiders will enter this contest with the comfort of defeating Houston in nine of their previous ten games, going 8-2 ATS during that time. Texas Tech did however trail 21-7 at the half last season at NRG Stadium but scored the next 31 points in a row to win 38-21.

Houston, who lost the yardage battle but won an overtime thriller 37-35 last week vs. UTSA, faced a significantly tougher challenge in their week one clash.  The Red Raiders welcomed FCS opponent Murray to Lubbock and defeated them 63-10 while covering as 38-point favorites.

Now, however, new Texas Tech head coach Joey McGuire welcomes in an experienced Houston team eager to get revenge from last season. With that top of mind, look for Cougars head ball coach Dana Holgerson to have a game plan up his sleeve that involves returning starting QB Clayton Tune slinging the ball throughout the day.

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Missouri +7.5 (-110)

On Saturday, when the two previous longtime Big 12 rivals square off for the first time since 2011, Missouri and Kansas State will both experience their first significant tests of the season. A defense that allowed just 11 yards on the run helped Missouri defeat Louisiana Tech (52-24) in the opening game last week. The victory was much greater than the box score might have you believe, as well, taking a 38-10 lead into the fourth quarter and then taking off the starters.

For Kansas State, the defense was also the standout in a season-opening victory over FCS South Dakota (34-0) last week. Deuce Vaughn, a Kansas State running back who gained 297 yards, sat out the majority of the second half as they coasted to the win.

In a game I have much closer to even on paper, I'm taking the touchdown plus in this one.

Week 2: Top College Football Parlay Picks @ +720 (Bet $100 to win $720)

  • UCF -5 (-110)
  • Houston ML (+125)
  • Missouri +7.5 (-110)

Article Author


Johnny has been covering the sports betting markets and handicapping games for the better part of the past decade. Along the way, he has written for publications such as All-In Magazine, Blitz Predict, FantasyPros, Betting Pros, Sportsbook Review, and most recently, OddsChecker. In addition to giving out picks on Twitter, Johnny is the host of the podcast The Daily Sports Bet -- a 10 minute or less listen with actionable insights and no fluff or BS. Starting the podcast in June, he closed out 2021 up 26 units with a winning percentage of 55%.


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