Kansas State vs. Oklahoma State Prediction, Pick, and Odds: Will Spencer Sanders Lead the Cowboys to Victory?

Kansas State vs. Oklahoma State Prediction, Pick, and Odds: Will Spencer Sanders Lead the Cowboys to Victory?

Kansas State couldn't keep up with TCU in Week 8, losing its second game of the season 38-28. Oklahoma State entered Week 8 as an underdog after losing to TCU in Week 7, but quarterback Spencer Sanders led the Cowboys to a 41-34 win over Texas. Sanders was busy as a passer, completing 34 of 57 attempts for 391 yards and two touchdowns against the Longhorns. The defense came through with three turnovers, securing a season-high three interceptions to outlast Quinn Ewers and Steve Sarkisian's potent offensive scheme.

The Big 12 is highly competitive at the top of the conference and both of these teams find themselves there, with both the Cowboys and Wildcats ranked inside the AP top 20. These are must-win games to preserve each program's ability to earn a berth in the Big 12 Championship game after the 2022 regular season. Last year, Oklahoma State mounted a second-half comeback to beat the Baylor Bears 21-16, so they have the experience in this Week 9 matchup. Will Sanders lead the Cowboys to a big road victory? Here are our picks, predictions, and odds for Saturday's matchup between the Oklahoma State Cowboys vs. Kansas State Wildcats.

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Kansas State vs. Oklahoma State Start Time and Where to Watch

Date: Saturday, October 29

Game time: 3:30 p.m. ET

Where to Watch: FOX

Kansas State vs. Oklahoma State Odds

Spread: Oklahoma State +1 (-105), Kansas State -1 (-110)

Total: Under 58 (-110), Over 58 (-110)

Moneyline: Oklahoma State (-110), Kansas State (-110)

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Kansas State vs. Oklahoma State Injury Report

Oklahoma State

WR Jaden Bray (Questionable - Undisclosed)

Kansas State

No injuries to report.

Kansas State vs. Oklahoma State Prediction

Kansas State's junior running back Deuce Vaughn is the engine that drives the Wildcats' offense. He was held to a season-low 23 rushing yards against Iowa State in Week 6, but Vaughn bounced back against TCU with a 6.9 YPC, finding the end zone and adding four receptions for an additional 38 yards. Quarterback Adrian Martinez transferred from Nebraska and has been a nice commodity for the Wildcats in 2022, utilizing his legs to rack up nine rushing touchdowns on nearly 100 carries. He has been much more limited as a passer, but Martinez still has four passing touchdowns to zero interceptions this year for Kansas State, making minimal mistakes.

Oklahoma State's defense is missing former DC Jim Knowles at Ohio State. It's a unit that is allowing 28.7 points per game to opponents, ranked 87th out of 131 FBS programs. Kansas State will be able to exploit the soft run defense deployed by the Cowboys, which has allowed TCU and Texas to rush for over 200 yards and five total touchdowns. The pass defense isn't much better, allowing big chunk plays but forcing quarterbacks to finish with under a 60 percent completion rate in five of seven games played. This means Martinez and Vaugh will need to be dominant in the rushing attack for the Wildcats in a plus-matchup.

Spencer Sanders is going to bring it against Kansas State's defense. They are more stout against the run than the pass, allowing Oklahoma, Texas Tech, and TCU to throw for over 300 yards and two touchdowns through the air. Sanders has been playing at an elite level all season for the Cowboys, utilizing his dual-threat ability to keep defenses honest and racking up production to manufacture wins. Kansas State could easily surrender three touchdowns and allow Sanders to post his fourth game with at least 290 passing yards this season.

The Wildcats are 3-1 at home and 4-3 ATS, while Oklahoma State is 5-2 ATS with one loss on the road against TCU a couple of weeks ago. Kansas State hasn't won this matchup since 2018, losing three consecutive games to the Cowboys. This is a pick'em spread, which means both of these teams are -110 to win outright. That's how close sportsbooks are opening up with this Week 9 conference matchup in the Big 12.

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Oklahoma State is averaging 44.7 points per game this season, which is over 15 points more than Kansas State. The defense may keep the Wildcats lingering for a bit, but I believe that Oklahoma State will be able to light up the scoreboard with one of the nation's most potent offenses against a defense that has allowed at least 28 points in three of its last four games. The Cowboys are a nice value to win outright on the road at -110 on the moneyline.

Kansas State vs. Oklahoma State Pick

• Pick: Oklahoma State Moneyline (-110) (Bet $110 to win $190)