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The Eagles surprised a lot of people in Week 1 with a dominating win. Can they keep it up in Week 2? Brian Good gives us his Eagles vs. 49ers prediction and pick

Philadelphia Eagles vs. San Francisco 49ers Week 2 Predictions: Against the Spread, Total, and Props

Sunday’s home opener for the Eagles is sure to be in front of an absolutely out-of-control Philadelphia fan base. The Linc is always loud, and to be completely honest there was very little expectation for this season around the city of Philadelphia. But, a blowout win in Week 1 changes all that.

Now, a team expected to compete for an NFC title comes into town in the San Francisco 49ers. Beating the Atlanta Falcons is one thing, taking on the 49ers and getting a win there is a completely different hurdle.

So, I decided to break down the game, what we can expect come Sunday and let you all in on how I’ll be betting the game with my picks.

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Philadelphia Eagles vs. San Francisco 49ers Week 2 Predictions

Philadelphia Eagles Preview

Let’s start with the good things we saw from the Philadelphia Eagles in Week 1, as there are plenty. For starters, Jalen Hurts was fantastic. He looked comfortable in Nick Sirrianni’s offense, took care of the ball and was accurate in the passing game. He also took off and ran when needed. It was awesome to see him come in and feel so comfortable right away.

Speaking of Sirrianni, he was also really good in his first ever game as a play caller. The Eagles had balance and their play design was creative, working on mismatches and targeting skill players they wanted to get involved.

The Philadelphia defense responded to a slow start by keeping Atlanta out of the end zone for the entire game and was better than anyone imagined.


I have some concerns for this week, especially when it comes to facing a good defensive unit. Hurts, for how fantastic he was, almost never stretched the field. His aDOT of 3.66 was the lowest in the NFL when it came to starting QBs in Week 1.

It also looked like the Eagles were running a lot of one-look passing schemes. Rarely, if ever, did we see Hurts working through progression and finding a man that worked his way open. Instead, the plays were usually quick hitters, designed for a single player.

It worked, and the Eagles looked awesome. But what about when the defense takes away the underneath stuff? Does Hurts have the capability to beat defenses that cheat down over the top?  I have a feeling we’ll find out this week.

San Francisco 49ers Preview

It was a tale of two halves for the 49ers in Week 1. In the first half, the 49ers absolutely dominated to the tune of a 31-10 lead. But the second half let the Lions climb back a bit in an eventual 41-33 win.

Jimmy Garoppolo, who is seemingly playing for his job every week, was good. He wasn’t asked to throw the ball a ton, just 25 times, but he completed 17 attempts for 314 yards.

As for their rushing attack, the 49ers imposed their will on the Lions. Elijah Mitchell finished with 19 carries for 104 yards and a touchdown. But, they also lost Raheem Mostert for the season with an injury. That will limit a little of what they can do on offense, especially when it comes to backs catching balls out of the backfield.

The injury bug also bit San Francisco on the defensive side as they lost CB Jason Verrett for the year with a torn ACL. But, the 49ers defense is still expected to be extremely strong this year, anchored by Fred Warner, Nick Bosa and Dre Greenlaw.

Complete Eagles vs. 49ers odds

San Francisco 49ers vs. Philadelphia Eagles Prediction

Can the Eagles, with a new starting QB, new WRs and a completely revamped back-end of their defense, really beat the 49ers in Week 2? It depends on a few things.

First, can Jalen Hurts take the top off of the 49ers defense? The secret is out. Teams know you want to run an offense similar to what Hurts ran at Oklahoma in order to play to his strengths. That can work in the NFL, but not without the threat of a deep ball. Devonta Smith, Jalen Reagor and Quez Watkins need to get open downfield if the Eagles are going to find success.

I think the group is talented enough to do that, but I’m not sure they find much of that success this week.

The second thing we need to see is can the Eagles' offense hang with the talent of the San Fran defense?

Jordan Mailata, just signed to a brand new deal, will have his hands full with Nick Bosa this weekend. We’re going to find out quickly if he’s worth the contract he just signed. Fred Warner is one of the best LB in the NFL and the San Francisco secondary, even without Verrett, is very good.

Week 1 gave me hope that this Eagles team can compete for an NFC East title, but I’m not going to overreact to Week 1 and take the Eagles against one of the NFL’s best teams when they’re getting just 3 points.

San Francisco 49ers vs. Philadelphia Eagles Pick

49ers -3 @ -105

Article Author


Brian is a sports journalist with close to ten years of experience in the business. A lifelong Philadelphia sports fan with a passion for all things sports gambling.


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