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Thursday Night Football features a huge divisional matchup between the Seattle Seahawks and Los Angeles Rams. Here are our staff's top picks for the game.

Thursday Night Football Picks: Our Staff's Top Bets for Seattle Seahawks vs. Los Angeles Rams

Nearly a quarter of the NFL season is in the books (and I say "nearly a quarter" because it sounds a heck of a lot better than "four seventeenths") and we finally get treated to a Thursday Night Football game we can watch with both eyes open.

After living through the riveting excitement of Panthers-Texans and Jaguars-Bengals the last two weeks, we got an NFC West rivalry matchup when the Los Angeles Rams travel to Seattle to take on the Seahawks.

In addition to an ever-growing abundance of top-notch content, our staff will be providing us with their favorite overall plays each week of the season.

For this piece, our staff will be covering whatever bets they feel strongest about for the Seahawks vs. Rams matchup -- no limitations. Let’s get to it!

Click here for complete Seahawks vs. Rams betting odds

Seattle Seahawks vs. Los Angeles Rams Picks

Los Angeles Rams -2.5 (-110)

Basic, I know, but I have a hard time trusting this Seahawks team, particularly on the short week. The Rams' offense looked discombobulated last week, but that's not something that will carry over into this week. Sean McVay and Matthew Stafford have hammered the bad defenses they've played this year, and the Seahawks currently rank 25th in defensive DVOA. Seattle's offense could go blow for blow, but I ultimately expect the Rams offense to be able to get away with whatever they want and control this game.

-- Derrik Klassen (@QBKlass)

This line makes no sense. The Rams are the far better team and should be favored by at least 4.5-5 points. This, of course, means that it’s a trap game and the Seahawks will come out and win by 10, but I’m falling for the trap anyway because I believe in the Rams that much. Last week, Stafford and the rest of LA ran into a buzz saw in Arizona, falling to the last unbeaten team in the NFL. This Seahawks team is not even in the same conversation as that Cardinals squad. With Stafford under center, Sean McVay has been able to open up the field in ways that he just couldn’t with Jared Goff. This Seahawks defense is bad and I expect to see the Rams offense tear them apart from the opening kick come Thursday night.

-- Brian Good (@BeGood1219)

Rams Moneyline (-139)

The Rams struggled defensively against the leading MVP candidate in Kyler Murray of the Arizona Cardinals. However, before that game, Los Angeles held the Buccaneers to 24 points, the Colts to 24 points, and the Bears to 14 points. The Rams have absolutely struggled in coverage but I love their pass rush to create chaos against a Seahawks offensive line that has been terrible in pass protection all year. Plus, Los Angeles should be able to get whatever they want offensively against a Seattle defense that has been even worse in coverage than the Rams this season.

-- Jason Radowitz (@Jason_Radowitz)

Rams Over 28.5 (+100) - BetMGM

Long gone are the days of the Legion of Boom. This Seattle defense is downright bad. They've allowed the fourth-most passing yards against this year and the only two teams they've held to under 30 points are the 49ers, who lost their starting quarterback during the game, and the Colts, who had Carson Wentz going with one working foot. Seven times since the start of last year has an opponent scored more than 28.5 points on this team and the Rams have gone over that number twice already this year. The number six overall offense against a team that's allowed 100 points against already? Sign me up.

-- Matt O’Leary (@MattOLearyNY)

Total: Under 54.5 (-104)

If this game were being played on a Sunday or Monday night, I would stay away from this total and instead focus on the point spread. However, the fact that this game is being played on a short week has me loving the under, which would be the first time the under cashes in a Rams game this year. Weird things happen on Thursday nights, and it is often evident that the offenses suffer from the extra lack of preparation. The last two Thursday night affairs have been low-scoring games, and the Seahawks have been one of the more profitable teams to the under this year, cashing it in three of their four games. Seattle has allowed 30+ points in two of their four games, but look for the 12th man to be the difference in keeping Los Angeles's scoring down this week.

-- Mike Spector (@MikeSpector01)

Cooper Kupp Over 84.5 Yards (-115)

An NFC West showdown that I'm not confident enough to pick a side in but I am plenty confident that the Stafford-to-Kupp connection will bounce back in a big way on a short week with less time to gameplan. Look for the Rams and Stafford to ride the ultra-reliable Kupp in what's expected to be a Thursday Night shoot-out.

-- Geoff Fienberg (@gfienberg17)

Darrell Henderson Over 64.5 Rushing Yards (-115)

Seattle has allowed the most rushing yards on the season to opposing running backs through the first four weeks (514). Henderson, when healthy, has been a workhorse running back for head coach Sean McVay and the Rams. In his two full games he's played in thus far, he has played 110 out of 120 possible snaps. McVay keeps Henderson on the field, and he has topped this total in those two games, rushing for 70 and 89 yards, respectively. Let's keep the streak going and cash another top play Thursday night. Best of luck if you tail!

-- Tom Viera (@Tom_Viera)

Darrell Henderson 50+ Rushing Yards and 15+ Receiving Yards (+125) - DraftKings

The Seahawks have been extremely generous to opposing running backs. How generous? Well, they've allowed the most rushing yards and the most receiving yards to the position. Yikes. Meanwhile, Darrell Henderson has eclipsed both 50 rushing yards and 15 receiving yards in each of his three games this season. It's also worth noting that his three highest snap shares have all come in 2021.

-- Elisha Twerski (@ElishaTwerski)

Article Author


The Senior Editor at OddsChecker, Elisha is an experienced fantasy and betting analyst. According to BettingPros, he was was one of the most accurate betting experts in 2019, ranking second in moneyline picks and 13th against the spread. Originally from Milwaukee, Wisconsin, his best skill is his ability to spell "Antetokounmpo" without looking. You can follow Elisha on Twitter at @ElishaTwerski.

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