Roma vs Real Madrid Lineups, Prediction, Betting Tips & Odds

Roma vs Real Madrid Match Summary

Roma welcome Real Madrid to the Stadio Olimpico in the Champions League, with more than 60,000 packing the stands in Rome for a proper European night under the lights.

Gian Piero Gasperini has openly praised Real Madrid's individual quality, but his Roma side are no pushovers. They carry a stubborn unbeaten run into a fixture that will test every inch of it.

José Mourinho returns to face the club he led to the UEFA Europa Conference League title in 2022, and his Real Madrid side arrive with real momentum behind them.

History leans hard towards the away side: Real Madrid are undefeated in their last seven matches against Roma in all competitions.

Roma vs Real Madrid Form

Roma are stubborn rather than spectacular right now. They are unbeaten in seven in all competitions. Draws in three of their last four, including Sunday's Serie A stalemate at Como where they kept a clean sheet after Donyell Malen saw red, tell you the wins have dried up. Paulo Dybala remains the man to unlock a tight defence.

Real Madrid have won four of their last five in all competitions, including a Champions League win over Serie A champions Inter. At the weekend they beat Villarreal despite Vinicius Junior's red card, which says plenty about the depth of an attack built around Kylian Mbappé and Jude Bellingham.

Roma vs Real Madrid Lineups & Team News

Injuries & Suspensions

Roma: B. Cristante (Injured/out), K. Koulierakis (Injured/out), M. Svilar (Injured/out)

Real Madrid: É. Militão (Injured/out), R. Asencio (Injured/out), Rodrygo (Injured/out)

Roma

Malen's red card against Como in Serie A does not carry a suspension into this one, so the forward is free to lead the line. Bryan Cristante is part of a three-man injury list with Koulierakis and Svilar, which leaves P. Gollini in line to start in goal.

Real Madrid

The Roma vs Real Madrid lineups get a boost on the away side: Eduardo Camavinga, Bernardo Silva and Arda Güler are all available again after missing the win over Inter. Vinicius Junior and Marc Cucurella should both start after being named on the bench against Villarreal, Denzel Dumfries could return at right-back and Dean Huijsen has served his suspension. Militão, Asencio and Rodrygo remain sidelined.

Roma vs Real Madrid Predicted Lineup

Roma

Formation: 3-4-2-1

Predicted Starting Lineup: P. Gollini, M. Hermoso, E. Ndicka, G. Mancini, Wesley, M. Koné, M. d. Roon, D. Rensch, M. Soulé, P. Dybala, D. Malen

Real Madrid

Formation: 4-2-3-1

Predicted Starting Lineup: T. Courtois, M. Cucurella, D. Huijsen, A. Rüdiger, D. Dumfries, A. Tchouaméni, F. Valverde, V. Júnior, J. Bellingham, A. Güler, K. Mbappé

Roma vs Real Madrid Key Stats & Match Facts

• There have been 12+ shots on target in 3 of the last 3 meetings between Real Madrid and Roma in the Champions League.
• There have been 28+ shots taken in 4 of the last 4 meetings between Real Madrid and Roma in the Champions League.
• Real Madrid have scored 2+ goals in 4 out of 4 matches against Roma in the Champions League.
• Roma have had 6+ corners in 4 of their last 4 matches against Real Madrid in the Champions League.

Roma vs Real Madrid Prediction & Best Bets

Our prediction: Real Madrid to win, with both sides finding the net, is the call for this Roma vs Real Madrid prediction. The away side are rated the clear favourites in the implied probability picture, and they simply have more ways to hurt a back three than Roma have to protect it. Roma's stubborn streak gives them enough to grab a goal at home, but Real Madrid at 20/21 with AK Bets is the pick in the Win Market.

Best Bets

Rodrigo Mora to have over 1.5 shots in the Player Shots market. Mora has been getting into good shooting positions regularly enough that this looks a fair edge against the implied probability in the price, and as a player prop it sits comfortably alongside a Real Madrid win in a fixture built for shots.

Bernardo Silva to be shown a card in the To Be Shown A Card market. Silva is back available for Real Madrid, and a feisty European night with plenty riding on it, plus the physical examination Roma's midfield will put him through, makes this one of our Roma vs Real Madrid best bets.

Roma vs Real Madrid Bet Builder

Our Roma vs Real Madrid bet builder tips combine a Real Madrid win, Kylian Mbappé finding the net, goals at both ends and Mario Hermoso to be shown a card.

Real Madrid have had 18+ shots in 3 out of 4 matches against Roma in the Champions League, and that sort of attacking volume backs the away win.

Mbappé leads the line for a side that has managed 7+ shots on target in 3 out of 3 matches against Roma in the Champions League.

Both teams finding the net carries a 64.5% implied probability in the projections. With Dybala and Soulé working behind Malen, Roma have the craft to find a goal of their own.

Hermoso faces a long evening in Roma's back three with Mbappé, Bellingham and Güler running at him. Defenders under that kind of sustained pressure tend to find their way into the book.

At the time of writing, this bet builder pays a best price of 10/1 and is as short as 6/1 elsewhere. That's a difference in potential winnings of R40 from best to worst price.

Shop around before placing this one, as the gap between operators on a four-leg builder like this can be significant: compare the full market via the Bet Builder Comparison Tool.

Bet builder odds correct at time of publishing.

Roma vs Real Madrid Talking Points

The headline storyline is Mourinho walking back into the Olimpico in the opposition dugout, his first match against Roma since leaving the club. On the pitch, the key battle is Real Madrid's front four against Roma's back three: Mbappé through the middle with Vinicius Junior and Güler wide will stretch Hermoso, Ndicka and Mancini all night. Gasperini summed up the danger himself: "That's what great teams and great players do." In the engine room, Valverde and Tchouaméni must shut down Dybala and Soulé between the lines, while referee François Letexier will need a firm hand in a fixture involving two sides who both had a man sent off at the weekend. The Roma vs Real Madrid betting odds lean towards the away side, and it is hard to argue with that.

Roma vs Real Madrid Predictions FAQs

When is the Roma vs Real Madrid Champions League game?

The match takes place on Wednesday 14 October 2026, with kick-off scheduled for 21:00 SAST.

Where is Roma vs Real Madrid being played?

The match is being played at the Stadio Olimpico.

Where can I watch Roma vs Real Madrid?

The fixture will be broadcast live on ESPN and TNT Sports 4.

What are the predicted lineups for Roma vs Real Madrid?

Roma's probable lineup includes P. Gollini, M. Hermoso, E. Ndicka, G. Mancini, Wesley, M. Koné, M. d. Roon, D. Rensch, M. Soulé, P. Dybala, and D. Malen. Real Madrid are expected to start T. Courtois, M. Cucurella, D. Huijsen, A. Rüdiger, D. Dumfries, A. Tchouaméni, F. Valverde, V. Júnior, J. Bellingham, A. Güler, and K. Mbappé.

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