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Genoa vs Juventus Lineups, Prediction, Betting Picks & Odds

Genoa vs Juventus Lineups, Prediction, Betting Picks & Odds

Genoa vs Juventus picks, lineups and odds for Serie A. Check team news, Same Game Parlay ideas and standout markets before Wednesday's game kicks off.

Genoa vs Juventus Game Preview

Competition

Italian Serie A

Game Date

Wednesday, October 28, 2026

Game Time

3:45 PM ET / 12:45 PM PT

Venue (City, Stadium)

Genoa, Luigi Ferraris

Genoa welcome Juventus to Luigi Ferraris for a Wednesday Serie A matchup, and our Genoa vs Juventus prediction leans firmly toward the visitors, the clear favorites on the moneyline.

Daniele De Rossi's Genoa sit 16th in the standings, yet home has been kinder to them lately: they are unbeaten in their last three home games.

Juventus sit seventh on 14 points and remain the stronger side, even with Locatelli, Yildiz and Thuram among a crowded list of absentees.

Juventus have won their last four games against Genoa in all competitions. Genoa are finally climbing, but snapping that run is what would turn a good week into a real statement.

Genoa vs Juventus Recent Results

Genoa have finally found a pulse. Mikael Ellertsson's strike from the edge of the box beat Venezia at home, capping a run that delivered six of their seven points this season. The catch: they have failed to score in each of their last three home games played on a Wednesday in Serie A, and this is a Wednesday kickoff.

Juventus arrive off a 2-0 win at Lecce, where Douglas Luiz set up Weston McKennie's opener and then scored the second himself before halftime. The bigger picture is patchier. A Juventus win would have landed 5 times out of their last 10 games against all opponents, so this squad has not been the machine its reputation suggests.

Genoa vs Juventus Lineups & Team News

Injuries & Suspensions

Genoa: J. Nuredini (Injured/out), L. Venturino (Injured/out), K. Ehizibue (Injured/doubtful), A. Amorim (Injured/doubtful), S. Wiafe (Injured/doubtful)

Juventus: N. González (Injured/out), K. Thuram (Injured/out), J. Ekhator (Injured/out), M. Locatelli (Injured/out), K. Grabara (Injured/out), K. Yildiz (Injured/out), Z. Çelik (Injured/out), F. Conceição (Injured/out)

Genoa

For the Genoa vs Juventus lineups, Daniele De Rossi sticks with a 3-5-2, with Bijlow in goal behind a back three of Marcandalli, Østigård and Vásquez. El Shaarawy and Ellertsson work the flanks around Traoré, Frendrup and Baldanzi, while Osmajić and Vitinha lead the line. Colombo is back from injury and starts on the bench. Nuredini and Venturino are out, and Wiafe, Amorim and Ehizibue face late fitness tests.

Juventus

Guglielmo Vicario starts in goal behind Lucumí, Bremer and Kalulu, with Cambiaso and McKennie at wing-back and Douglas Luiz and Sarr in central midfield. Alajbegović is tipped to start in the attacking midfield role, though it is a toss-up between him and Koopmeiners. Kolo Muani and Woltemade pair up front again. Locatelli, Yildiz, Thuram, Grabara, Ekhator, Çelik, González and Conceição are all unavailable.

Genoa vs Juventus Predicted Lineup

Genoa

Formation: 3-5-2 (probable)

Predicted Starting Lineup: Probable: J. Bijlow; A. Marcandalli, L. Østigård, J. Vásquez; M. Ellertsson, H. Traoré, M. Frendrup, T. Baldanzi, S. El Shaarawy; M. Osmajic, Vítinha

Juventus

Formation: 3-4-1-2 (probable)

Predicted Starting Lineup: Probable: G. Vicario; J. Lucumí, Bremer, P. Kalulu; W. McKennie, Douglas Luiz, P. M. Sarr, A. Cambiaso; K. Alajbegovic; N. Woltemade, R. Kolo Muani

Genoa vs Juventus Key Stats & Game Facts

  • Genoa have failed to score in 5 of their last 5 games vs Juventus in Serie A.
  • Genoa have received 2+ cards in 7 of their last 8 games in Serie A.
  • Junior Messias has won 3+ fouls in 3 of his last 4 appearances in Serie A.
  • Dusan Vlahovic has scored or assisted in 3 of his last 3 appearances vs Genoa in Serie A.
  • Morten Frendrup has made 4+ tackles in 3 of his last 5 appearances vs Juventus in Serie A.

Genoa vs Juventus Prediction & Best Picks

Our Prediction

Our prediction is Juventus 2-1. The visitors are clear favorites at -115 (Polymarket), and the soccer case backs up the price. Juventus thrive on attacking set pieces and like to control games in the opposition's half, while Genoa struggle to finish and to defend counter attacks. Genoa's aggressive, ball-winning approach at home can get them on the scoreboard against this opponent for once, but Kolo Muani and Woltemade give Juventus the extra punch to take the points. That view shapes our Genoa vs Juventus best picks below.

Best Picks

Over 2.5 in the Total Goals Over/Under market. It fits a Juventus-leaning match with a projected total of about 2.7 goals. In the Total Goals Over/Under market, the projected total sits just above the line, and Juventus do most of the heavy lifting in it. The AI probability on this line beats the implied probability of the best price, so there is real value here. Genoa's recent blanks against Juventus keep it a moderate-confidence play, but it fits a game where the hosts finally get one.

Randal Kolo Muani Over 1.5 in the Player Fouls market. He is expected to lead Juventus's front line again. Kolo Muani is a near lock to start up top for Juventus, and he is the focal point of the attack with Woltemade alongside him. Leading the line against an aggressive Genoa side that loves to steal the ball should mean plenty of physical duels and fouls conceded.

Genoa vs Juventus Same Game Parlay

Our Genoa vs Juventus Same Game Parlay picks lean into a physical, card-heavy game, combining a Johan Vásquez card, Genoa team cards and Daniele Rugani fouls across three legs.

Johan Vásquez To Be Shown A Card: the Genoa defender has been carded in 3 of his last 4 appearances in Serie A, and he plays in a side that never backs off.

Over 1.5 Total Home Team Cards: Genoa have received 3+ cards in 3 of their last 4 games in Serie A, and their aggressive style plays right into this line.

Daniele Rugani Over 1.5 Player Fouls: he has committed 2+ fouls in 5 of his last 5 appearances vs Genoa in Serie A. He sits outside the probable XI, so check the team sheet.

That is where we stop. Every leg tells the same story, a messy, stubborn game full of whistles, and that beats forcing an extra selection.

Make sure to get the best odds on your Same Game Parlay with Oddschecker's Exclusive Same Game Parlay Comparison Tool.

Same Game Parlay odds correct at time of publishing.

Genoa vs Juventus Talking Points

Luciano Spalletti shut down claims that his players dictate formations, saying "My players wouldn't dare to dictate the system we play with," and he praised Genoa as a difficult opponent, both tactically and for the atmosphere at their stadium. That respect is earned. Genoa play aggressive, direct soccer built on long balls and width down the left, and they are good at stealing the ball. Juventus want the opposite, possession and control in the opposition's half, so the midfield battle matters most, with Alajbegović or Koopmeiners tasked with unlocking a stubborn block. The Genoa vs Juventus betting odds have Juventus well clear, and nothing in this matchup argues otherwise.

Genoa vs Juventus Predictions FAQs

When is the Genoa vs Juventus Italian Serie A game?

The game kicks off at 3:45 PM ET / 12:45 PM PT on Wednesday.

Where is Genoa vs Juventus being played?

The game is being played at Luigi Ferraris, with Genoa as the home side.

Who are the probable lineups for Genoa vs Juventus?

Genoa's probable lineup is J. Bijlow, A. Marcandalli, L. Østigård, J. Vásquez, S. E. Shaarawy, H. Traoré, M. Frendrup, T. Baldanzi, M. Ellertsson, M. Osmajic and Vítinha. Juventus' probable lineup is G. Vicario, J. Lucumí, Bremer, P. Kalulu, A. Cambiaso, D. Luiz, P. M. Sarr, W. McKennie, K. Alajbegovic, N. Woltemade and R. K. Muani.

Which players are missing for Genoa vs Juventus?

Genoa are missing J. Nuredini and L. Venturino through injury, with K. Ehizibue, A. Amorim and S. Wiafe doubtful. Juventus are missing N. González, K. Thuram, J. Ekhator, M. Locatelli, K. Grabara, K. Yildiz, Z. Çelik and F. Conceição, all injured.

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