NFL Futures

The undefeated San Francisco 49ers travel to Seattle for an NFC West matchup between two of the conference's strongest teams. Can San Francisco remain perfect on the road while Sam Darnold and Seattle try to turn home field into a divisional advantage? Check out this 49ers vs. Seahawks prediction and best bet for Sunday, October 11.

The Denver Broncos travel to Los Angeles looking to rebound from a road loss against a Chargers team still searching for its first win. Can Justin Herbert finally turn competitive performances into a victory while Denver's defense tries to dictate another AFC West matchup? Check out this Broncos vs. Chargers prediction and best bet for Sunday, October 11.

The Detroit Lions travel to Arizona with both teams trying to rebound from disappointing Week 4 losses. Can Jared Goff and Detroit rediscover their early-season scoring form while Arizona attempts to exploit a Lions defense that struggled in Carolina? Check out this Lions vs. Cardinals prediction and best bet for Sunday, October 11.

The USC Trojans travel across the country for a primetime White Out matchup against the Penn State Nittany Lions at Beaver Stadium. Can Rocco Becht and a Penn State team desperate to stop a two-game slide respond against Jayden Maiava and one of the Big Ten’s most explosive passing offenses? Check out this USC vs. Penn State prediction and best bet for Saturday, October 10.

The Minnesota Golden Gophers travel to West Lafayette for a Big Ten matchup against a Purdue Boilermakers team coming off its biggest victory in several seasons. Can Ryan Browne and Purdue build on an upset at Illinois against Drake Lindsey and a Minnesota team riding consecutive conference wins? Check out this Minnesota vs. Purdue prediction and best bet for Saturday, October 10.

Jeremiah Smith has surged from +750 in the last update to the first odds-on favorite of the 2026 Heisman race, while Darian Mensah, Keelon Russell and CJ Carr remain the leading quarterback challengers. Check out the latest Heisman Trophy odds entering Week 6 of the college football season.

Tyreek Hill’s next-team market has swung sharply toward a reunion with the Kansas City Chiefs after injuries reshaped the team’s receiving corps in Week 4. With Hill coming off a declining final stretch in Miami and now looking for his next opportunity, Kansas City has quickly emerged as the most logical destination. Here are the latest Tyreek Hill next-team odds and what is driving the move.

Arch Manning leads the 2027 NFL Draft first-pick odds as college football’s top prospects begin building their cases. Can Dante Moore, CJ Carr or a rising challenger overtake the Texas quarterback? Check out the latest NFL Draft No. 1 pick odds and outlook for six leading contenders.

Texas-Tennessee headlines a loaded Week 4 slate, while Ole Miss-Florida, Oregon-USC and Texas A&M-LSU provide three more ranked matchups with major conference implications. Check out the best college football games to watch in Week 4, including start times, TV information and the latest odds.

Buffalo, Seattle and San Francisco strengthened their places near the top in Week 2, while Baltimore, Chicago and the Chargers stumbled and dropped. Check out the latest NFL Power Rankings entering Week 3 of the 2026 season.