St. Louis City vs San Diego FC Lineups, Prediction, Betting Picks & Odds

St. Louis City vs San Diego FC Game Preview

St. Louis City host San Diego FC at Energizer Park on Halloween. A playoff-bound team trying to stop a skid meets visitors with nothing left to play for.

St. Louis City have already locked up a postseason berth under first-year head coach Yoann Damet. They come in stinging from a 3-2 home loss to Portland Timbers, though.

San Diego FC were knocked out of playoff contention after a 4-1 road loss to Vancouver Whitecaps. Mikey Varas' side are playing for pride now, and it shows.

The previous meetings belong to the visitors. San Diego have two wins and a tie in this matchup, and St. Louis are still waiting on their first win against them.

St. Louis City vs San Diego FC Recent Results

St. Louis City have dropped three straight in MLS, and opponents have carved open their defense every time. The cup has been kinder: they lifted the Lamar Hunt U.S. Open Cup earlier this month, beating Columbus Crew on penalties for the first major trophy in club history. Rafael Navarro, who scored late against Portland, is the man to watch up top.

San Diego FC have failed to win their last 10 MLS games, and their back line has been a sieve through the whole slide. Anders Dreyer is the bright spot, leading the club with 14 goals in MLS this season. The through-ball creativity hasn't gone anywhere. The results have.

St. Louis City vs San Diego FC Lineups & Team News

Injuries & Suspensions

St. Louis City: Roman Bürki (Injured/out), Alexandru Matan (Injured/out), Kyle Hiebert (Injured/out), Brendan McSorley (Injured/out), Palmer Ault (Injured/out)

San Diego FC: Elias Achouri (Injured/out), Osvald Søe (Injured/out)

St. Louis City

First-choice goalkeeper Roman Bürki is out with a concussion, so Ben Lundt is the probable starter in goal. Tomás Ostrák is available again after serving his suspension in midweek. Jeong Sang-Bin and Fallou Fall are both expected to start, which shapes the St. Louis City vs San Diego FC lineups around a 3-4-1-2 with Rafael Navarro up front.

San Diego FC

Mikey Varas could bring Onni Valakari back into midfield for the trip to Energizer Park. Osvald Søe and Elias Achouri are both unavailable, and Anders Dreyer and Cédric Bakambu are probable starters in the front three.

St. Louis City vs San Diego FC Predicted Lineup

St. Louis City

Formation: 3-4-1-2 (probable)

Predicted Starting Lineup: Ben Lundt; Dante Polvara, Timo Baumgartl, Fallou Fall; Rafael Santos, Chris Durkin, Daniel Edelman, Conrad Wallem; Carlo Holse; Jeong Sang-Bin, Rafael Navarro

San Diego FC

Formation: 4-3-3 (probable)

Predicted Starting Lineup: Pablo Sisniega; Kieran Sargeant, Christopher McVey, Manu Duah, Oscar Verhoeven; Gabriel Pirani, Aníbal Godoy, Onni Valakari; Anders Dreyer, Cédric Bakambu, Amahl Pellegrino

St. Louis City vs San Diego FC Key Stats & Game Facts

• There have been 4+ goals scored in 9 of San Diego FC's last 9 games (Major League Soccer).
• St. Louis City have scored 2+ goals in 8 of their last 10 games (Major League Soccer).
• Rafael Navarro has recorded 1+ shots on target in 9 of his last 9 appearances (Major League Soccer).
• Anders Dreyer has scored or assisted in 6 of his last 7 appearances (Major League Soccer).
• Carlo Holse has attempted 4+ shots in 4 of his last 5 appearances (Major League Soccer).

St. Louis City vs San Diego FC Prediction & Best Picks

Our Prediction

Our St. Louis City vs San Diego FC prediction is a home win, but don't count on a clean sheet. The hosts go in as moneyline favorites, and their best weapon is attacking down the wings, which should cause real problems for a San Diego defense that does a poor job of stopping opponents from creating chances. The visitors still play enough sharp through balls to find the net, so expect a messy, high-scoring St. Louis win rather than a shutout.

Best Picks

St. Louis City to win, in the Moneyline market. The projections make St. Louis the favorites with roughly a 49% win probability, and they rate the hosts as the stronger attacking side. San Diego have failed to win their last 10 MLS games, so backing a slumping visitor makes little sense.

Both Teams To Score: Yes. San Diego have conceded multiple goals in each of their last 9 games in Major League Soccer, so St. Louis should find the net. On the other side, the leaky St. Louis back line gives Dreyer and company a way back in, and the projections put both teams scoring at about a 70% probability.

St. Louis City vs San Diego FC Same Game Parlay

Our same game parlay picks for this matchup back a shootout: Navarro on target, Holse shooting freely, Dreyer to score and over 3.5 total goals.

Rafael Navarro Over 0.5 in the Player Shots On Target market. The striker has put at least one shot on target in each of his last 9 Major League Soccer outings.

Carlo Holse Over 3.5 in the Player Shots market. The attacking midfielder isn't shy, having attempted 4+ shots in 4 of his last 5 appearances in Major League Soccer.

Anders Dreyer in the Anytime Goalscorer market. The forward has scored in 3 of the last 4 games he has played in Major League Soccer, and this defense is wide open.

Over 3.5 goals on the Total Goals Over/Under line, at +110 (Polymarket). San Diego FC games have produced 4+ goals in 9 of their last 9 in Major League Soccer.

Shop around before placing this parlay: Oddschecker's Same Game Parlay Comparison Tool lines up the prices side by side.

Same Game Parlay odds correct at time of publishing.

St. Louis City vs San Diego FC Talking Points

St. Louis brought in Rafael Navarro as a Designated Player from Colorado Rapids in September, and this is a good game for him to get his shooting boots back on before the playoffs. Aerial duels are another edge: St. Louis are strong in the air, while San Diego struggle there. For San Diego, it's a steep fall. Mikey Varas led the club to the top of the Western Conference in its 2025 expansion season, and now they're playing out the string. The betting odds cast the visitors as clear moneyline underdogs, and that's about right for a team this out of sorts.

St. Louis City vs San Diego FC Predictions FAQs

When is the St. Louis City vs San Diego FC MLS game?

The game is on Saturday, October 31, 2026, at 3:00 PM ET / 12:00 PM PT.

Where is St. Louis City vs San Diego FC being played?

The game is being played at Energizer Park.

What are the probable lineups for St. Louis City vs San Diego FC?

St. Louis City's probable formation is 3-4-1-2 and San Diego FC's is 4-3-3. Probable starters include Ben Lundt, Timo Baumgartl and Rafael Navarro for St. Louis City, and Pablo Sisniega, Anders Dreyer and Cédric Bakambu for San Diego FC.

Which players are injured for St. Louis City and San Diego FC?

For St. Louis City, Roman Bürki, Alexandru Matan, Kyle Hiebert, Brendan McSorley and Palmer Ault are listed as injured. For San Diego FC, Elias Achouri and Osvald Søe are listed as injured.

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