Lecce vs Genoa Lineups, Prediction, Betting Picks & Odds

Lecce vs Genoa Game Preview

Only a point separates Genoa and Lecce in the Serie A standings, and our Lecce vs Genoa prediction starts right there. On Sunday at the Via del Mare, the hosts badly need a response.

Eusebio Di Francesco's Lecce sit 14th and are reeling, with a defense that keeps springing leaks. Home-field advantage is the main thing they have going for them right now.

Daniele De Rossi's Genoa sit 13th and arrive with real momentum. They are the favorite in this matchup, and the moneyline backs that view against a Lecce side that can't stop conceding.

History pulls the other way, though. Lecce are undefeated in their last 5 home games against Genoa in all competitions, so the visitors have something to prove on this field.

Lecce vs Genoa Recent Results

Lecce are in a full-blown slump, with four losses in their last five games, capped by a crushing 5-1 defeat away to Frosinone in midweek. The back line is the problem. Konan N'Dri and Amar Fatah on the flanks carry most of the burden of creating anything going forward.

Genoa have won three of their last four, and the headline result was an impressive 2-0 win over Juventus. That run has them above Lecce in the standings, with Tommaso Baldanzi pulling the strings behind Vitinha and Milutin Osmajić. The only real question is fatigue after that big effort.

Lecce vs Genoa Lineups & Team News

Injuries & Suspensions

Lecce: Medon Berisha (Injured/out), Santiago Pierotti (Injured/out), Lassana Coulibaly (Injured/out), Ivan Ilic (Injured/out), Willem Geubbels (Injured/doubtful), Kialonda Gaspar (Suspended)

Genoa: E. Havel (Injured/out), Lorenzo Venturino (Injured/out), Mikael Ellertsson (Injured/doubtful)

Lecce

The Lecce vs Genoa lineups start with a question mark in the home attack. Di Francesco has to check on Geubbels, and if he doesn't recover, Paco Esteban is the favorite over Stulic to lead the line between N'Dri and Fatah. Gaspar serves the second game of his suspension after his red card against Juventus, so Jamil Siebert partners Tiago Gabriel in the middle of the defense. Midfield is settled, with Coulibaly, Ilic and Berisha all still sidelined.

Genoa

De Rossi could make some changes from the win over Juventus. Ellertsson is a doubt on the left flank with an ankle problem, and Mario Mitaj is ready to step in. Hamed Traorè is expected to come into midfield to give Amorim a rest, while Baldanzi is heading toward a start behind Vitinha and Osmajić, even with El Shaarawy pushing hard for a spot.

Lecce vs Genoa Predicted Lineup

Lecce

Formation: 4-3-3 (probable)

Predicted Starting Lineup: Wladimiro Falcone; Danilo Veiga, Jamil Siebert, Tiago Gabriel, Antonino Gallo; Youssef Maleh, Oumar Ngom, Mohamed Kaba; Konan N'Dri, Paco Esteban, Amar Fatah

Genoa

Formation: 3-5-2 (probable)

Predicted Starting Lineup: Justin Bijlow; Alessandro Marcandalli, Leo Østigård, Johan Vásquez; Mario Mitaj, Hamed Traorè, Morten Frendrup, Tommaso Baldanzi, Kingsley Ehizibue; Milutin Osmajić, Vítinha

Lecce vs Genoa Key Stats & Game Facts

• Genoa have received 2+ cards in 7 of their last 10 games vs Lecce in Serie A.
• There have been 11+ shots on target in 6 of Lecce's last 9 games in Serie A.
• Patrizio Masini has won 2+ fouls in 3 of his last 3 appearances vs Lecce in Serie A.
• Youssef Maleh has made 3+ tackles in 3 of his last 4 appearances vs Genoa in Serie A.
• Genoa have failed to score in 3 of their last 4 games vs Lecce in Serie A.

Lecce vs Genoa Prediction & Best Picks

Our Prediction

Our prediction is a Genoa win in a game where both sides find the net. Lecce's back line is far too generous right now, and Genoa carry a 43.05% win probability, comfortably clear of the hosts. Lecce can nick one on the counter or from a set piece, but Genoa have the momentum and the better shape, and +163 (Polymarket) on the moneyline is a fair price for the better team.

Best Picks

Over 2.5 goals in the Total Goals Over/Under market. Lecce have seen over 2.5 goals in five of their last six Serie A games. The Total Goals Over/Under market is where the first of our Lecce vs Genoa best picks lives, with the projection sitting at 2.72 total goals. Lecce leak far too much at the back, and Genoa have enough going forward to push this one over the line.

Both teams to score: Yes, in the Both Teams To Score market. Lecce have conceded at least twice in five of their last six league games. The Both Teams To Score market fits everything else in this preview. The both-teams-to-score probability of 54.84% sits above the implied probability of the Yes price, and Lecce's set-piece threat gives the hosts a real route to goal even on a bad day.

Lecce vs Genoa Same Game Parlay

Our Lecce vs Genoa same game parlay picks combine a Johan Vásquez card, Over 1.5 Genoa cards, Genoa on the moneyline and Over 2.5 total goals.

Vásquez has been carded in 3 of his last 5 Serie A appearances. Genoa play an aggressive style, and a tense bottom-half matchup puts the center back right in the firing line.

Over 1.5 Total Away Team Cards has landed in 7 of Genoa's last 9 games. Lecce love through balls and direct play, so the Genoa defenders will be scrambling plenty.

Genoa on the moneyline anchors this parlay. Their AI probability sits at 43%, and the visitors bring the kind of momentum this Lecce side simply lacks.

Over 2.5 goals is +150 (Polymarket) on its own, and it suits a messy matchup where a leaky Lecce back line meets a confident Genoa attack.

Make sure to get the best odds on your Same Game Parlay with Oddschecker's Exclusive Same Game Parlay Comparison Tool.

Same Game Parlay odds correct at time of publishing.

Lecce vs Genoa Talking Points

The Lecce vs Genoa betting odds lean toward the visitors, but set pieces are where the hosts can bite back. Lecce have scored 5 goals from dead balls in Serie A this season, and attacking set pieces rank among their real strengths. The flip side is the start. Lecce have conceded 9 goals in the opening half hour of Serie A games this season, so an early Genoa push could quiet the Via del Mare in a hurry. Genoa's poor scoring record against Lecce is the one thing that gives the hosts hope, but this version of the Lecce defense looks like the one most likely to let that run slip.

Lecce vs Genoa Predictions FAQs

When is the Lecce vs Genoa Serie A game?

Lecce vs Genoa is a Serie A game in the 2026/2027 season, played on Sunday, November 1, 2026 with kickoff at 12:00 PM ET / 9:00 AM PT.

Where is Lecce vs Genoa being played?

The game is being played at Stadio Ettore Giardiniero - Via del Mare, Lecce.

What formations are expected for Lecce vs Genoa?

The probable lineups list Lecce in a 4-3-3 formation and Genoa in a 3-5-2 formation.

Which team is favored to win Lecce vs Genoa?

Genoa are listed as the favorite, with a 43.05% win probability against 31.48% for Lecce and 25.47% for a tie.

Affiliate Disclosure

We are not a gambling or betting operator, but we receive a commission from these companies when we advertise their brands and refer customers to them (affiliate marketing). We provide information, odds information and links to websites of these companies. Some of the information made available on our site may be positioned as a result of a commission paid to us by a third party. We do not take or place bets/transactions and any information on Our Products is provided for entertainment purposes only.

Please gamble responsibly. 21+.