Sassuolo vs Fiorentina Lineups, Prediction, Betting Picks & Odds

Sassuolo vs Fiorentina Game Preview

Two of the leakiest defenses in Serie A meet at MAPEI Stadium - Città del Tricolore on Monday, and our Sassuolo vs Fiorentina prediction leans toward the visitors in a game built for goals.

Sassuolo sit 15th in the standings under Alberto Aquilani. Injuries to Jay Idzes, Ismaël Koné and Fedde Leysen, plus the suspended Kristian Thorstvedt, leave him short of bodies.

Fiorentina sit 17th under Paolo Vanoli. They create plenty going forward, but a defense that has conceded 21 Serie A goals keeps undoing the good work.

Fiorentina hold the edge in previous meetings with three wins. Sassuolo have two, and the other ended in a tie, so the visitors carry a slight advantage into kickoff.

Sassuolo vs Fiorentina Recent Results

Sassuolo have lost their last three games in Serie A, and the defense is the problem. They have conceded at least two goals in 6 of their last 7 Serie A games. Domenico Berardi and Armand Laurienté still give them a real threat on the break, but the back line keeps handing games away.

Fiorentina have failed to win 9 of their last 10 games in Serie A, so their favorite tag comes from the matchup, not momentum. They have conceded at least two goals in 8 of their last 9 Serie A games, yet Franco Mastantuono keeps driving the attack from the right with Mateo Pellegrino leading the line.

Sassuolo vs Fiorentina Lineups & Team News

Injuries & Suspensions

Sassuolo: Fedde Leysen (Injured/out), Ismaël Koné (Injured/out), Jay Idzes (Injured/out), Kristian Thorstvedt (Suspended)

Fiorentina: Marin Pongračić (Injured/out), Arthur Atta (Injured/out), Fabiano Parisi (Injured/out), Luca Ranieri (Injured/doubtful)

Sassuolo

The probable Sassuolo vs Fiorentina lineups have Alberto Aquilani sticking with a 4-3-3 and Stefano Turati in goal. Nemanja Matić anchors the midfield alongside Darryl Bakola and Vasilije Adžić, while Domenico Berardi and Armand Laurienté flank Sebastiano Esposito up top. Thorstvedt's suspension takes away a midfield option.

Fiorentina

Paolo Vanoli mirrors that 4-3-3 with David de Gea in goal. Radu Drăgușin and Viery pair up at center back, Nicolò Fagioli sits in front of them, and Franco Mastantuono and Alieu Njie support Mateo Pellegrino. Luca Ranieri is doubtful and misses out on the probable XI.

Sassuolo vs Fiorentina Predicted Lineup

Sassuolo

Formation: 4-3-3 (probable)

Predicted Starting Lineup: Stefano Turati; Simone Cinquegrano, Cas Odenthal, Duje Ćaleta-Car, Josh Doig; Darryl Bakola, Nemanja Matić, Vasilije Adžić; Domenico Berardi, Sebastiano Esposito, Armand Laurienté

Fiorentina

Formation: 4-3-3 (probable)

Predicted Starting Lineup: David de Gea; Álex Jiménez, Viery, Radu Drăgușin, Valde; Marco Brescianini, Nicolò Fagioli, Cher Ndour; Franco Mastantuono, Mateo Pellegrino, Alieu Njie

Sassuolo vs Fiorentina Key Stats & Game Facts

• Fiorentina have received 2+ cards in 10 of their last 10 games against Sassuolo in Serie A.
• There have been 11+ shots on target in 6 of Sassuolo's last 9 games in Serie A.
• Franco Mastantuono has won 3+ fouls in 4 of his last 4 appearances in Serie A.
• Armand Laurienté has attempted 3+ shots in 6 of his last 9 appearances in Serie A.
• Both teams have scored in 8 of the last 10 meetings between Sassuolo and Fiorentina in Serie A.

Sassuolo vs Fiorentina Prediction & Best Picks

Our Prediction

Our prediction is a Fiorentina win. The visitors are rated favorites, and Sassuolo come in missing key bodies through injury and suspension. Neither defense inspires any trust, so don't expect a stubborn, low-event grind. The difference is creativity: Fiorentina have more of it, with Mastantuono attacking from the right and Fagioli running the midfield.

Best Picks

Over 2.5 goals in the Total Goals Over/Under market. Goals have been a feature of both sides' recent Serie A games. The Total Goals Over/Under market is the cleanest of our Sassuolo vs Fiorentina best picks. The projected total sits at 3.65 goals. Over 2.5 has also landed in 8 of Fiorentina's last 9 Serie A games.

Fiorentina to win in the Moneyline market. The model rates the visitors as favorites against Sassuolo. Take the visitors on the Moneyline. Fiorentina carry a 46% win probability, clearly ahead of the hosts, and Sassuolo have lost their last three Serie A games while missing Idzes, Koné and Leysen.

Sassuolo vs Fiorentina Same Game Parlay

Our Sassuolo vs Fiorentina same game parlay picks lean on player props: Mastantuono shots, a Berardi card, an Adžić goal and a Berardi shot on target.

Franco Mastantuono Over 1.5 Player Shots: the winger has attempted 2+ shots in each of his last 8 Serie A outings, and Sassuolo struggle against attacks down the wings.

Domenico Berardi To Be Shown A Card: his last four Serie A games produced three bookings, and opponents tend to play aggressively against Fiorentina.

Vasilije Adžić Anytime Goalscorer: the midfielder has scored in three of his five most recent Serie A appearances, and he gets a crack at a Fiorentina defense that leaks goals.

Domenico Berardi Over 0.5 Player Shots On Target: facing Fiorentina in Serie A, he has put at least one effort on target in 8 of his previous 10 appearances.

Make sure to get the best odds on your Same Game Parlay with Oddschecker's Exclusive Same Game Parlay Comparison Tool.

Same Game Parlay odds correct at time of publishing.

Sassuolo vs Fiorentina Talking Points

Alberto Aquilani faces his old club here. He made 81 appearances for Fiorentina as a player and later coached their Under-18 and Primavera sides. Across the field, Paolo Vanoli called this an important game but refused to label it a season-defining watershed. That reads like a coach managing pressure, because both defenses rank among the most porous in the division and somebody's back line will get exposed on Monday.

Sassuolo vs Fiorentina Predictions FAQs

What is the predicted score for Sassuolo vs Fiorentina?

Our prediction is a Fiorentina win in an open game with goals at both ends.

When is the Sassuolo vs Fiorentina Italian Serie A game?

The game is on Monday, November 2, 2026, at 12:30 PM ET / 9:30 AM PT.

Where is Sassuolo vs Fiorentina being played?

Sassuolo vs Fiorentina is being played at MAPEI Stadium - Città del Tricolore.

What formation are Sassuolo and Fiorentina expected to use?

Both Sassuolo and Fiorentina are listed with a 4-3-3 probable formation.

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