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Top 5 Betting Picks for Saturday, November 22nd - Expert Predictions & Value Plays for Saturday's CFB Slate

The Wolf is targeting a stacked college football slate on Saturday afternoon, looking for winners in the Nebraska vs. Penn State game and others. Check out these top player props and AI advantages for Saturday, November 22nd.

The Wolf - November 22, 2025, 1:20 PM EST

5 Minute Read

Top 5 Betting Picks for Saturday, November 22nd: Finding Value on Nebraska vs. Penn State Props and More

College football’s coaching carousel is spinning at full speed, and with chaos comes opportunity. As programs fight for relevance, bowl positioning, and job security, The Wolf is out hunting for the best player prop edges on the board. Saturday’s slate gives us a mix of Big Ten grinders, Big 12 fireworks, and late-night Mountain West value.

These five plays rise above the rest. FairPlay AI is giving us clear advantages across receiving and rushing markets, and with postseason implications everywhere, expect players to be pushed to full usage. Here are the data backed edges The Wolf is pouncing on.

Looking for advanced AI predictions and props to enhance your CFB betting? Try out oddschecker+ now on this limited time 7-day free trial!

The Wolf Top 5 Betting Picks - Saturday, November 22nd

1. Nyziah Hunter (Nebraska) Over 34.5 Receiving Yards (-115) Check out the best odds at FanDuel Sportsbook

  • EV: 52.23%
  • AI Probability: 81.45%
  • Hit Rate: 7 of last 10 games

Hunter has become one of Nebraska’s most stable pass catchers down the stretch, consistently beating soft zones and creating YAC opportunities. Against a Penn State defense that has shown cracks in the intermediate passing game, Hunter should again see enough volume to clear this number comfortably.

2. Devonte Ross (Penn State) Over 24.5 Receiving Yards (-114) Check out the best odds at FanDuel Sportsbook

  • EV: 50.63%
  • AI Probability: 80.24%
  • Hit Rate: 5 of last 10 games

Ross is a perfect matchup fit against a Nebraska secondary that allows chunk plays in spread alignments. His target share has stabilized, and when he gets even modest usage, this line becomes far too low. The Wolf loves Ross as one of Saturday’s cleanest edges.

3. Eli Raridon (Notre Dame) Over 34.5 Receiving Yards (-114) Check out the best odds at FanDuel Sportsbook

  • EV: 44.02%
  • AI Probability: 76.72%
  • Hit Rate: 6 of last 10 games

Notre Dame's tight end continues to be a core piece of the passing game, especially on third downs. His route participation has climbed, and FairPlay AI projects a strong efficiency bump against a Syracuse defense that struggles with TE seam routes. This is a high-probability usage spot. With a blowout likely, Raridon will have extra opportunities in garbage time as well.

4. Evan Pryor (Cincinnati) Over 29.5 Rushing Yards (-115) Check out the best odds at FanDuel Sportsbook

  • EV: 72.66%
  • AI Probability: 92.38%
  • Hit Rate: 7 of last 10 games

One of the biggest EV advantages on the entire Saturday slate. Pryor’s burst and workload trend make this an over worth attacking aggressively. When he gets 6 to 8 touches, he nearly always clears this number, and FairPlay AI expects even more involvement this weekend.

5. O’Mega Blake (Arkansas) Over 54.5 Receiving Yards (-114) Check out the best odds at FanDuel Sportsbook

  • EV: 21.21%
  • AI Probability: 64.57%
  • Hit Rate: 8 of last 10 games

Blake is a pure volume monster and the engine of this passing attack. His consistency makes him one of the most reliable overs on the board. With multiple 60 plus yard games already this season, this line sits below his true performance level.

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