England v Argentina - Saturday 14:30, Sky Sports 2
England should give up 17 points to Argentina. Not because the Pumas will be weak in defence like Fiji were last Saturday or because they are demoralised and injury-hit like South Africa were the Saturday before. But because Eddie Jones has got England in the zone and kept them there throughout his 11-straight wins and they are not only fully aware of Argentina's traditional strengths at the set-piece and growing stature of tactics such as electric darts around the fringes and offloads for angled runners, they know how to counter them because they do the same tactics better.
The Pumas are also coming to the end of a hard season and getting into back-to-back intense one-score battles with Wales and Scotland should tell on their legs as the game goes on - as should a high penalty count on the scoreboard - and the Red Rose replacements have a knack of stretching opponents past their elastic limit.
Jones and his forwards henchman Steve Borthwick have got England playing with a new level of guile and purpose and plenty of the players in this matchday 23 have had experience of beating the Pumas by 19, 25 and 29 points in their three 2013 meetings. Skipper Dylan Hartley, pack colleagues Dan Cole and Courtney Lawes (Tom Wood remained on the bench) and scrum-half Ben Youngs were involved in the teams' hard-fought 2011 World Cup Pool B battle.£10 Free Credit and a £500 Deposit Bonus
Scotland v Georgia - Saturday 14:30, BBC1
The Scotland camp this week should have been a happy place after they built on their brave defeat to Australia with a hard-fought, well-deserved, last-gasp win over Argentina at Murrayfield. But they won't be over-confident about crushing Georgia in Kilmarnock like a 25-point handicap suggests.
Scotland suffered a humiliating loss to Tonga on their autumn travels up to Aberdeen in 2012 and only beat the Lelos 15-6 (tryless game) at the 2011 World Cup. Georgia have gone up a gear again in the last five years too, with the two wins over Tonga and Namibia at the last World Cup being their focus rather than testing Argentina and New Zealand, and last Saturday's success over Samoa should have put them spot on for the challenge.
Scotland will look to stretch Georgia with expansive play, especially as they have a reshuffled midfield because of an injury and Rugby Park's artificial pitch, where they avenged that Tonga turnover in 2014 with 37-12 triumph, should help this aim.
Backline stars Stuart Hogg, Tommy Seymour and Alex Dunbar all crossed that day in Kilmarnock but the bet is Outside Centre Mark Bennett to dot down for a seventh try in 17 Tests at 13-10.
Wales v South Africa - Saturday 17:30, BBC1
Wales have not been impressive in any of their three autumn outings so far but will see this an ideal opportunity to secure just a second win over South Africa in their last 19 meetings.
These Springboks are a mere shell of previous vintages most especially last year's World Cup bronze medallists, who battled past the Red Dragons in a dramatic quarter-final. They were stubborn but outclassed by England a fortnight ago and sunk to new depths in defeat to Italy last Saturday.
The Boks are better than that loss to the Azzurri but it is hard to see how confidence can be restored quick enough to do more than compete in what should be a cauldron of bubbling home fans at Cardiff's Principality Stadium.
The absence of Wales skipper Sam Warburton is a blow but there are still plenty of wise heads in their team including Alan Wyn Jones and Jonathan Davies, while the extra mobility of replacement Seven Justin Tipuric may be a blessing in disguise. And fit-again Number Eight Taulupe Faletau will give them a huge boost off the bench.
Another livewire performer, Scrum-Half Gareth Davies, should be backed for a try at 5-2. Davies scored Wales' try in that 2015 World Cup loss against the Boks and was their only bright spot in defeat to Australia three weeks ago. England Nines Ben Youngs and Danny Care found themselves with the freedom of Twickenham against South Africa and Davies has more pace than them.