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Floyd Mayweather Jr. vs. Manny Pacquiao 2 Odds, Date, How to Watch, and Early Predictions for September Rematch

Floyd Mayweather Jr. and Manny Pacquiao are taping up the gloves one last time after their epic battle over a decade ago. With both coming out of retirement for this rematch at nearly 50 years old, what should we expect for the September clash on Netflix? Peter Alexis breaks down the latest Floyd Mayweather Jr. vs. Manny Pacquiao 2 early odds.

Peter Alexis - February 25, 2026, 3:00 PM EST

5 Minute Read

Floyd Mayweather Jr. vs. Manny Pacquiao 2 Odds: Does Pacquiao Stand a Chance in Rematch of Retired Legends?

They are doing it again.

More than a decade after the most lucrative fight in boxing history, Floyd Mayweather Jr. and Manny Pacquiao will meet for a rematch on Saturday, Sept. 19, streamed globally on Netflix. The original bout on May 2, 2015 ended in a unanimous decision win for Mayweather and generated record breaking revenue. At the time, many fans believed the fight came five years too late. Now, at ages 49 and 47, they are stepping back into the ring once more.

The announcement sent immediate shockwaves through the combat sports world. Both men are long retired from traditional title contention. Mayweather officially closed his career at 50-0 after stopping Conor McGregor in 2017, while Pacquiao retired in 2021 before briefly returning in 2025. Yet nostalgia, streaming money, and unfinished business appear to be enough to bring them back together.

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Floyd Mayweather Jr. vs. Manny Pacquiao 2 Odds

  • Moneyline: Floyd Mayweather Jr. (-175), Manny Pacquiao (+150), Draw (+1400)

Mayweather is currently favored in the rematch at -175, meaning a $10 bet returns about $15.71 if he wins. Pacquiao is the underdog at +150, offering a $25 return on a $10 bet. A draw is available at +1400. These odds reflect respect for Mayweather’s technical brilliance and undefeated record, while still acknowledging Pacquiao’s ring activity and hunger for redemption.

Mayweather’s defensive mastery and ring intelligence have allowed him to age gracefully in exhibition settings, and bettors still view that skill set as giving him an edge even at 49. Pacquiao’s aggressive style, southpaw angles, and recent activity make him a live dog, but sustaining volume and sharpness over the full distance at 47 remains a question.

Floyd Mayweather Jr. vs. Manny Pacquiao 2 Date, Time, and Where to Watch

  • Date: Saturday, September 19, 2026
  • Time: 11:30 PM E.T.
  • Where to Watch: Netflix

Click here for complete Mayweather Jr. vs. Pacquiao 2 Odds

Floyd Mayweather Jr. vs. Manny Pacquiao 2 Fight Records

Shakur Stevenson (50-0)

Floyd Mayweather Jr. retired with a perfect professional boxing record of 50 wins and zero losses, including 27 knockouts across five different weight classes. His official mark, according to extensive boxing archives, shows flawless performance in every sanctioned bout he contested from his debut in 1996 until his last sanctioned fight in 2017.

Mayweather is widely considered one of the greatest defensive fighters in history. He won world titles in multiple divisions from super featherweight to super welterweight and retired without defeat after a TKO victory over Conor McGregor. In the first Mayweather vs. Pacquiao fight, he controlled range and tempo to earn a unanimous decision over 12 rounds. Though he has kept active in exhibitions since retiring, this Netflix rematch will mark a rare professional contest after nearly a decade away from official scoring.

Manny Pacquiao (62-8-3)

Manny Pacquiao boasts a professional boxing record of 62 wins, 8 losses, and 3 draws, with 39 victories by knockout. He is the only boxer in history to win major world titles in eight different weight divisions, a feat unmatched in modern boxing lore.

Pacquiao first retired in 2021 but returned to the ring in 2025, earning a majority draw against Mario Barrios in a welterweight title fight. His career has spanned three decades and brought some of the sport’s most memorable moments, including victories over elite contenders across multiple weights. At 47, he seeks to hand Mayweather his first official professional loss, a narrative he has openly discussed in promotional interviews.

Floyd Mayweather Jr. vs. Manny Pacquiao 2 Odds Breakdown

Their first fight came late in both careers, with Mayweather at 38 and Pacquiao at 36, a timing many analysts felt was too late for their primes. The rematch elevates age as an even bigger factor. Mayweather has not had a sanctioned professional fight since 2017, though he has remained in the sport through exhibitions. Pacquiao’s activity is more recent, and his competitive shape in 2025’s Barrios fight raised eyebrows.

Ultimately, this event blends spectacle with sport. The presence of Netflix as a global platform continues the trend of streaming giants reshaping boxing’s biggest stages. Whether the fight is competitive or skewed by age, it will likely be one of the year’s most watched combat sports events.

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