UFC 322 Odds: Betting Odds for Every Fight on the UFC 322 Card at Madison Square Garden
UFC 322 is headlined by Islam Makhachev's lightweight title defense, while also getting a co-main thriller with Valentina Shevchenko as a slight favorite in women's flyweight. Let's take a look at the complete UFC 322 betting card odds ahead of Saturday's fights at Madison Square Garden in New York City.
Peter Alexis - November 14, 2025, 10:45 AM EST
5 Minute ReadUFC 322 Odds: Betting Odds for Every Fight on the UFC 322 Card
UFC 322 returns to Madison Square Garden in New York City on November 15, bringing one of the most electric fight lineups of the fall to the historic arena. The card is headlined by welterweight champion Islam Makhachev, who puts his title on the line against rising star Jack Della Maddalena in a matchup that blends elite grappling, sharp striking, and a clash of two surging careers. Makhachev has built a near perfect 27 and 1 résumé and enters as a strong favorite to extend his run of dominance.
The rest of the main card delivers plenty of intrigue. Former flyweight queen Valentina Shevchenko meets the always dangerous Zhang Weili in a high level title fight, while top contenders Sean Brady and Michael Morales battle for position in the welterweight rankings. Leon Edwards also returns against knockout specialist Carlos Prates, and veteran Beneil Dariush looks to stop the rise of Benoit Saint Denis in a lightweight showdown. With multiple divisions in play, UFC 322 brings a balanced mix of championship stakes and contender drama.
Here is a full breakdown of the UFC 322 betting odds and outlook for each main card fight.
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UFC 322 Date, Time, and Where to Watch
- Date: Saturday, November 15, 2025
- Time: 9:00 PM ET (Main Card)
- Where to Watch: ESPN+ PPV
Click here for complete UFC 322 odds
Jack Della Maddalena (+220) vs. Islam Makhachev (-275): Welterweight title
Makhachev once again enters a title fight as a sizable favorite, carrying a -275 number that reflects both his dominance and his stylistic reliability. His chain wrestling, control grappling, and increasingly polished striking make him a puzzle few opponents have solved. Della Maddalena brings crisp boxing and strong finishing ability, but slowing Makhachev’s pressure and neutralizing his takedowns will be a steep challenge. Oddsmakers are clearly siding with the champion to retain and push his record to an even stronger position in the pound for pound discussion.
Click here for complete Maddalena vs. Makhachev odds
Valentina Shevchenko (-135) vs. Zhang Weili (+110): Women’s flyweight title
This matchup brings together two of the most skilled women in UFC history. Shevchenko enters as the slight favorite thanks to her technical precision and deep championship experience. Zhang brings explosive offense and a willingness to push a high pace, which gives her a real path to victory if she can disrupt Shevchenko’s rhythm. The narrow split in odds reflects how close this fight projects to be, with the market giving the former champion a slight edge based on stylistic control.
Click here for complete Shevchenko vs. Weili odds
Sean Brady (-145) vs. Michael Morales (+120): Welterweight
Brady comes in as the favorite due to his elite grappling base and top control, something that has troubled nearly every opponent he has faced. Morales is one of the brightest young prospects in the division and holds the striking advantage, but he will need to keep the fight standing to cash as the underdog. The odds suggest a competitive fight with Brady’s wrestling being the key separator.
Click here for complete Brady vs. Morales odds
Leon Edwards (+165) vs. Carlos Prates (-200): Welterweight
Prates is favored at -200 as he continues to build momentum with a string of decisive finishes. His pressure and power make him a dangerous assignment for anyone, but Edwards brings experience, footwork, and tactical striking that can keep him competitive in extended exchanges. The oddsmakers are trusting Prates to land the more impactful moments, especially in a three round setting.
Click here for complete Edwards vs. Prates odds
Beneil Dariush (+165) vs. Benoit Saint Denis (-200): Lightweight
Saint Denis enters as the -200 favorite thanks to his relentless pace, durability, and constantly improving skill set. Dariush remains a live underdog with strong grappling and veteran savvy, but recent setbacks have shifted the confidence of bettors. Saint Denis has been surging, and the market expects his pressure and cardio to carry him late if the fight turns into a grind.
Click here for complete Dariush vs. Saint-Denis odds
UFC 322 Prelims - Betting Odds
Fighter 1 Odds | Fighter 2 Odds |
|---|---|
Bo Nickal (-225) | Rodolfo Vieira (+185) |
Roman Kopylov (+140) | Gregory Rodrigues (-170) |
Erin Blanchfield (-250) | Tracy Cortez (+200) |
Malcolm Wellmaker (-165) | Cody Haddon (+135) |
Kyle Daukaus (-400) | Gerald Meerschaert (+310) |
Pat Sabatini (+135) | Chepe Mariscal (+110) |
Angela Hill (+375) | Fatima Kline (-500) |
Baisangur Susurkaev (-1000) | Eric McConico (+700) |
MMA ODDS & PICKS
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