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Rams v Bills Odds: How to Bet on Thursday Night Football

Check out our OddsChecker guide on how to bet LA Rams v Buffalo Bills, so you can secure the best odds and offers, for this NFL Week 1 Opener.
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Rams v Bills Odds: How to Bet on Thursday Night Football

The first Thursday Night Football game, and the NFL 2022 Regular Season opener is right around the corner, as the LA Rams v Buffalo Bills game takes place this Thursday, September 8th, in Los Angeles.

Below, we will provide a how to bet guide on this huge showdown, between the reigning Super Bowl Champions, and the favorites for this year's renewal. Included will be the best odds and promo codes you will find, in the lead up to this game.

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We will provide you with the best promo codes, including the DraftKings promo code and FanDuel promo code, both of which guarantee a combined payout of $350!

Rams v Bills Odds

Here are the latest odds for the LA Rams v Buffalo Bills. We will include the Moneyline Odds, Spread and Total, courtesy of DraftKings Sportsbook. Some odds and lines may differ depending on when you are accessing this article and what sportsbook you are using.

Claim the DraftKings promo code and FanDuel promo code now, and you can turn a combined $10 stake into $350 total, guaranteed!

LA Rams v Buffalo Bills


  • LA Rams +115
  • Buffalo Bills -135


  • LA Rams +2.5


  • Over/Under 53.5
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Best Rams v Bills Betting Promos - Lock in $350 Guaranteed

Here are our favorite Rams v Bills promo cods, which you can parlay into $350 worth of fee bets, just from a $10 stake. The best part is the DraftKings promo code and FanDuel promo code are both guaranteed, meaning you will win, no matter what the result of your opening bets on this one are!

DraftKings Promo Code: Bet $5, Get $200 on the Rams or Bills

With the latest DraftKings promo code, you will turn $5 into $200 no matter what, when betting LA Rams v Buffalo Bills, in this first Thursday Night Football clash of the season.

It doesn't matter whether you bet the Rams or the Bills in this one, you will instantly get $200 guaranteed from your first $5 bet, and then any profit from a winning bet would be added. That is a 40x return on your initial investment, thanks to the DraftKings promo code.

The Rams are coming off a Super Bowl win and get to start their season at home, and while the Bills are the current favorites for this year's Lombardi Trophy, the offense may need to adapt in the early weeks, with Brian Daboll now gone. This then suggests a wager on the LA Rams may well be worth it.

Without the DraftKings promo code, a $5 wager on the Rams would secure $10.75 in total if they won. With this extremely generous offer though, that $10.75 becomes $210.75 if they win, and $200.00, even if the Rams lose!

Claim this DraftKings promo code, by following the how to claim steps below:

Step One: CLICK HERE or on the offer button below to lock in the DraftKings promo code and attach it to your new account

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Step Two: Complete your registration with DraftKings Sportsbook

Step Three: Make a deposit and place a $5 bet on your chosen NFL Week 1 market

Step Four: Get $200 guaranteed, win or lose, thanks tot he DraftKings promo code

FanDuel Promo Code: Bet $5, Win $150 on Rams v Bills

If you already have a DraftKings Sportsbook account or have just signed up, now is the time to focus your attention on another 'bet and get' offer, via the FanDuel promo code.

A $5 wager will turn into $150 worth of bonuses immediately, when you have claimed this FanDuel promo code. So like the DraftKings offer, you will win no matter what, and will get the chance to keep any profit made on the $5 wager as well.

You could play both sides, and take both teams on different sites if you wanted to, or stick to your convictions on either the Rams or the Bills and try and boost your profits even further, on top of the $350 worth of guaranteed bets you have locked in, after claiming these two offers.

That is a 30x payout, and effectively boosts either the Bills or Rams to 30-1 odds, so boost your NFL Week 1 bankroll now, by betting on the first game of the week, with the FanDuel promo code.

Follow these steps below, and claim the FanDuel promo code now, to win more on NFL Week 1, right away!

Step One: CLICK HERE or the claim button below, to add this FanDuel promo code to your account registration

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Step Two: Complete your FanDuel Sportsbook sign up

Step Three: Deposit and wager $5 on your favorite NFL market in September

Step Four: Get an instant and guaranteed $150, even if your bet loses, thanks to the FanDuel promo code

Bet365 Promo Code: Bet $1, Get $200 Guaranteed on Rams v Bills

Bet365 Colorado just launched, so now we have this excellent sportsbook offering in both the New Jersey sports betting market, and Colorado sports betting market.

As this offer starts to become available to a wider audience, we think it is important to share for those that can claim the Bet365 promo code.

This is by far the biggest bet and get offer out there, as you turn a $1 bet into $200 guaranteed, so claim this Bet365 promo code in time for this Rams v Bills Thursday Night Football opener, and give your bankroll a huge increase, ahead of NFL Week 1 betting over the weekend.

Claim this Bet365 promo code by clicking the offer button below, and following the on-screen instructions.

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Now we want to take a look at the best promo codes on the market, for those that want to bet BIG, but cover themselves against any upsets. With the BetMGM bonus code and the Caesars Sportsbook promo code you will be able to bet over $2000 without fear of losing.

BetMGM Bonus Code: $1000 Risk Free Bet on Rams v Bills

Here, you will be able to claim the BetMGM bonus code and get yourself a $1000 risk free bet, on any Rams v Bills market.

If betting big is on your radar ahead of Thursday Night Football, there is no better way than to claim this BetMGM bonus code, and the upcoming Caesars Sportsbook promo code, so you can bet over $2000, knowing your stakes will be returned with a loss.

You could be keen on the Rams Moneyline, the Bills to cover their spread, or know that it will be a high-scoring game and want to bet on the total. No matter where you want to go with your first wager, bet up to $1000 risk free, with the BetMGM bonus code.

Click the offer button below, and follow the instructions, to claim this BetMGM bonus code now, and give yourself $1000 to play with in Week 1 of the NFL season.

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Caesars Sportsbook Promo Code: Get Your First Bet on Caesars!

You will get your first bet (up to $1250) on Caesars, when you claim this Caesars Sportsbook promo code below.

This offer means you can bet up to $1250 on Rams v Bills, and any losses incurred with that bet, will be returned up, up to that amount. Claim this Caesars Sportsbook promo code now, and bet with more confidence, as you go 'Full Caesar' on this Thursday Night Football action.

Caesars Sportsbook is a huge operator in the sports betting market, and is now live in PA and Kansas as well, so there has never been a better time to claim the Caesars Sportsbook promo code.

Claim this $1250 Bet on Caesars, by clicking the offer button below, and following the onscreen instructions to sign up in your state. Ensure you are using the code OCUS1FULL to claim this $1250 bet, 1,000 Reward Credits® and 1,000 Tier Credits.

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Best Rams v Bills Betting Markets

When it comes to what markets to bet on, in the Rams v Bills Thursday Night Football showdown, these are the most popular markets. We will give an example on each to help break down, what is required to win your first wager!


The Moneyline wager is simple. You are betting on which team you think will win, and regardless of how they get the job done, your bet will win if they do. They could win by 20 in regular time, or by 1 point in overtime, your Moneyline bet will come in regardless, if your team is victorious.

Here are the current Moneyline odds, via DraftKings Sportsbook, for the LA Rams v Buffalo Bills.

  • LA Rams +115
  • BUF Bills -135

If you think the LA Rams can stamp their authority early at home, then bet them with the DraftKings promo code now, and you will turn $5 into $200 if they lose, and $210.75 if they win!

A $5 bet on the Bills at odds of -135 would usually only return $8.70 total if they won, but with the $150 bonus you get from the FanDuel promo code, this would then be $158.70. If they did lose, at the hands of the LA Rams, then $150 would still hit your FanDuel Sportsbook account.

Spread Betting

When it comes to spread betting, you are looking at how many points a team will win (or lose) by, and whether they can cover that number.

While the Bills are favored to win, both the Rams and the Bills have been given odds of -110 to cover their spread. These lines move often but the Bills have been a -2.5 favorite for a while in this one. To cover, the Bills need to win by three or more, for the Rams, they need to lose by 2 points or less.

This is signified by the odds and market below:

  • LA Rams +2.5 (-110)
  • BUF Bills -2.5 (-110)

Two things you will see differently when betting on NFL Lines in the spread market, rather than the Moneyline market, is the odds are closer, and the underdog could still be the favorite to cover the spread. In this case, the spread market cannot be split, and DraftKings Sportsbook give both teams an equal chance of covering.

The reason you see may see .5 point lines in spread betting is to avoid a 'push'. As this line is set at -2.5, the chance of a push is removed. A push would occur if the LA Rams were +2 on the spread and lost by 2, or the Bills were -2 on the spread and won by 2. This means a win or lose would not occur.

If you think the Rams can cover their spread, claim the FanDuel promo code now, and you will turn $5 into $150 even if they fail to cover, and if they do cover that line, you will keep the profit from your bet on top as well.

With the DraftKings promo code, you could go all in on the Bills to cover the line, and if they fail to do so, you will still turn $5 into $200 guaranteed.

Anytime Touchdown Scorer

The Anytime Touchdown Scorer market is a fun way to stay engaged in the action all game long.

In the Anytime Touchdown Scorer market, you are betting on an individual to score a touchdown. If you bet on a quarterback, they would have to run one in, think Lamar Jackson or Josh Allen, or catch one in the end zone, think Nick Foles and the Philly Special.

The anytime touchdown lines are already out for next Thursday's LA Rams v Buffalo Bills encounter and here are a selection of the favorites to score a touchdown in the game, and their respective odds.

  • Cooper Kupp -140
  • Gabe Davis +120
  • Cam Akers +125
  • Stefon Diggs +130
  • Allen Robinson +40
  • Josh Allen +170

A lot is made of the Josh Allen - Stefon Diggs connection through the air, and Josh Allen's rushing ability, so both of those looks decent value to score a touchdown at plus-money, in a game they are slated to win. Gabe Davis is slated to have a huge season for the Buffalo Bills however, and it is hard to predict which way Allen may go with the ball. That is why both of these receivers are plus-money odds, while someone like Cooper Kupp is odds-on, because we know Matthew Stafford will rely on him heavily.

Bet on this market with the DraftKings promo code or FanDuel promo code now, and you will turn $5 into $200 or $150 respectively, even if your player fails to get in the end-zone.


Tom Jacobs is the host of the Lost Fore Words golf podcast and has been writing betting articles on golf for the past decade. Tom also co-hosts the DP World Tour Picks & Bets show on the Mayo Media Network, so has his finger on the pulse on all the major Tours. A long-suffering Nottingham Forest fan, Tom also enjoys watching Soccer at the weekend, and was delighted to see his Forest team win promotion this season!


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