WWE Wrestlemania 41 Betting Odds, Match Card, Picks, Predictions: John Cena, Tiffany Stratton Among Favorites

Wrestlemania 41 is gearing up for its annual two-night event in Las Vegas, Nevada this weekend. Catch Wrestlemania in prime time on Saturday and Sunday night from Allegiant Stadium, returning to Sin City for the first time in over 30 years.

All eyes are on the Undisputed WWE Championship between Cody Rhodes and John Cena on Sunday night. However, there's a lot of quality matchups and narratives to unpack on the rest of the Wrestlemania 41 betting card. Who wins the Triple Threat match during Saturday's main event on Night 1? Can Gunther pull off a huge upset against Jey Uso in the World Heavyweight Championship? Will Charlotte Flair dethrone Tiffany Stratton in the WWE Women's Championship?

Here's a look at the full card for the upcoming Wrestlemania 41 primetime event in Las Vegas, Nevada on Saturday and Sunday night.

Get your first month of oddschecker+ right now for just $0.99. Don't miss out on this April deal!

WWE WRESTLEMANIA 41 TIME AND WHERE TO WATCH

• Date - Saturday, April 19, 2025 - Sunday, April 20, 2025
• Game Time - 7:00 p.m. ET
• Where - Allegiant Stadium - Las Vegas, NV
• Where to Watch - Peacock, Netflix (Internationally)

WRESTLEMANIA 41 CARD

Night 1 (Saturday, April 19)

• Main Event (Triple-threat match): Seth Rollins vs. Roman Reigns vs. CM Punk
• World Heavyweight Championship: Gunther (c) vs. Jey Uso
• WWE Women's Championship: Tiffany Stratton (c) vs. Charlotte Flair
• World Tag Team Championship: War Raiders (c) vs. The New Day
• WWE United States Championship: LA Knight (c) vs. Jacob Fatu
• Rey Mysterio vs. El Grande Americano
• Jade Cargill vs. Naomi

Night 2 (Sunday, April 20)

• Main Event - Undisputed WWE Championship: Cody Rhodes (c) vs. John Cena
• WWE Women's World Championship (Triple-Threat): Iyo Sky (c) vs. Rhea Ripley vs. Bianca Belair
• Women's Tag Team Championship: Liv Morgan & Raquel Rodriguez (c) vs. Bayley & Lyra Valkyria
• WWE Intercontinental Championship (Fatal Four-Way): Bron Breakker (c), vs. Dominik Mysterio vs. Penta vs. Finn Balor
• Sin City Street Fight: Damian Priest vs. Drew McIntyre
• AJ Styles vs. Logan Paul

Wrestlemania 41 BETTING ODDS, PICKS, AND PREDICTIONS

UNDISPUTED WWE CHAMPIONSHIP - CODY RHODES VS. JOHN CENA ODDS

Cody Rhodes is currently in the midst of his first reign as Undisputed WWE Champion. He's an underdog against John Cena, who infamously turned heel for the first time in his career at the WWE Elimination Chamber.

Will the heel win? Or will the current Undisputed WWE Champion, Rhodes, manage to deliver an upset? Siding with the younger talent and backing Rhodes in this spot at plus money feels realistic. Rhodes is a big value at this price.

Undisputed WWE Championship Pick - Cody Rhodes (+150)

Click Here for Complete Wrestlemania 41 Odds

WORLD HEAVYWEIGHT CHAMPIONSHIP - GUNTHER VS. JEY USO ODDS

Jey Uso is an overwhelming favorite to beat Gunther during the World Heavyweight Championship at -600 odds. Uso is coming off of a win earlier in 2025 at the men's Royal Rumble.

Gunther is being undervalued at +350 odds in this heavyweight tilt. He's won numerous events, including as the longest-reigning Intercontinental Champion in WWE history. Gunther also beat Uso in other World Title and Intercontinental Title matches.

There's virtually no value to land on Uso in this match. A half unit on Gunther winning as a heavy underdog nets a bit short of two units of profit. Gunther provoked Uso to pick him in this Heavyweight Championship but he'll have a great chance to record the upset on Night 1.

World Heavyweight Championship Pick - Gunther (+350)

Click Here for Complete Wrestlemania 41 Odds

UNITED STATES CHAMPIONSHIP - LA KNIGHT VS. JACOB FATU

LA Knight is the defending United States Championship title winner going up against Jacob Fatu. Yet, oddsmakers have Fatu valued as a -300 favorite.

LA Knight could wind up physically overmatched in this United States Championship event. Odds have shifted in favor of Knight, dropping from -500 to -300 on Fatu.

Underdogs could be in a position to make an impact at Wrestlemania 41. Odds have shortened on most underdogs, including LA Knight, who is now +225 to successfully defend his title.

United States Championship Pick - LA Knight (+225)

Click Here for Complete Wrestlemania 41 Odds

WWE WOMEN'S WORLD CHAMPIONSHIP (TRIPLE-THREAT) - IYO SKY VS. RHEA RIPLEY VS. BIANCA BELAIR

All three fighters in the Women's World Championship Triple-Threat are available to bet at plus odds right now. Sky is the defending champion but her odds are +175, longer than betting favorite Bianca Belair at +110 odds. Rhea Ripley holds value at +350 as well.

Belair's addition to make this a Triple-Threat format has made her the odds-on favorite at +110. Siding with the defending champion, Sky, at +175 feels like the right move during the WWE Women's World Championship on Night 2.

WWE Women's World Championship (Triple-Threat) Pick - Iyo Sky (+100)

Click Here for Complete Wrestlemania 41 Odds

WWE WOMEN'S CHAMPIONSHIP - TIFFANY STRATTON VS. CHARLOTTE FLAIR

Tiffany Stratton will attempt to defend her WWE Women's Championship belt against Charlotte Flair during Night 1 on Saturday night at Wrestlemania 41. Flair's odds are close to a pick'em, so expect a back-and-forth matchup between both fighters.

The value is on Stratton to defend her title at -110 odds but Flair is a 14-time champion who returned from injury earlier this season. She chose to challenge Stratton, who just defeated Nia Jax on SmackDown in early January 2025.

Flair is motivated and has plenty of experience. These two factors are likely why oddsmakers favor her over Stratton ahead of Saturday night's WWE Women's Championship match.

WWE Women's Championship Pick - Charlotte Flair (-130)

Click Here for Complete Wrestlemania 41 Odds