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OG Anunoby Knicks

Cavaliers vs. Knicks Same Game Parlay: Can Lonzo Ball, OG Anunoby Make an Impact in Season Opener?

The Knicks and Cavs will get their seasons started on Wednesday night as the two leading favorites in the Eastern Conference. Who will cement themselves as the top dog in this early-season battle for supremacy? Peter Alexis analyzes this Cavs vs. Knicks game with a same game parlay, targeting new Cleveland addition, Lonzo Ball.

Cavaliers vs. Knicks Same Game Parlay: Targeting Lonzo Ball, OG Anunoby in Wednesday's Season Opener

The Cavaliers and Knicks face off in one of the marquee matchups of NBA Opening Night, with two Eastern Conference contenders looking to start strong after deep playoff runs last season. Cleveland opened last year with a record-breaking 15-game win streak, and they’ll try to capture that same early momentum in 2025. Both teams were eliminated by the Pacers in last year’s playoffs, but the Cavaliers’ loss came first, while the Knicks reached the Eastern Conference Finals before bowing out in six games. These squads have similar talent levels and physical play styles, setting up a competitive season opener at Madison Square Garden.

This three-leg same game parlay targets value across the board, focusing on new arrivals and reliable contributors who can make an immediate impact. Cleveland is slightly favored, and we’re banking on them to come out on top with the help of their newest point guard, plus a strong rebounding effort from one of New York’s key wings.

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Cavaliers vs. Knicks Date, Time, and Where to Watch

  • Date: Wednesday, October 22, 2025
  • Time: 7:00 PM ET
  • How to Watch: ESPN

Cavaliers vs. Knicks Odds

Click here for the latest Cavaliers vs. Knicks Odds

Cavaliers vs. Knicks Same Game Parlay

Leg 1: Cavaliers ML

Cleveland has proven to be one of the league’s most complete teams when healthy, led by their defensive intensity and backcourt scoring. They’ve shown the ability to get out to hot starts and control the pace early in the season, and this matchup lines up well against a Knicks team that often struggles to contain athletic guards like Donovan Mitchell.

Leg 2: Lonzo Ball Over 7.5 Points

After joining the Cavaliers in a July trade from Chicago, Ball is eager to prove he’s still a high-level playmaker and scorer. His fit next to Mitchell and Darius Garland should open up plenty of transition and catch-and-shoot opportunities. With a relatively low points line, Ball’s energy and confidence in his Cleveland debut make this one of the better early-season prop values on the board.

Leg 3: OG Anunoby Over 4.5 Rebounds

Anunoby was one of the Knicks’ most consistent rebounders last year, using his athleticism and strength to crash the glass from the wing. At a 67% AI probability of cashing, this total sits too low given his workload and rebounding tendencies in physical matchups like this. Expect him to remain aggressive on both ends, giving this leg strong upside to close out the +480 parlay.

Cavaliers vs. Knicks Same Game Parlay (+480) Click here to get these best odds on FanDuel Sportsbook

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