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DePaul vs. Creighton Prediction, Pick Against the Spread, Latest Odds for Big East Tournament Quarterfinal

The Creighton BlueJays and DePaul Blue Demons will square off in the Big East Tournament Quarterfinals on Thursday night. Can Ryan Kalkbrenner and the BlueJays dominate against DePaul in this conference tournament clash? Next Level Bets provides his pick against the spread for DePaul vs. Creighton in the Big East Tournament.

Next Level Bets - March 13, 2025, 1:33 PM EDT

4 min

DePaul vs. Creighton Prediction, Pick Against the Spread, Latest Odds for Big East Tournament Quarterfinal

We’ve got an intriguing Big East Tournament matchup tonight as Creighton takes on DePaul. DePaul comes into this game as a big underdog, looking to pull off another upset after shocking Georgetown last week. Meanwhile, Creighton has been strong all season and will look to handle business against a struggling DePaul squad.

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DePaul vs. Creighton Odds

DePaul vs. Creighton Date, Time, and Where To Watch

  • Date: March 13, 2025
  • Time: 7:00 pm ET
  • Where To Watch: Fox Sports 1

Click here for latest DePaul vs. Creighton Odds

DePaul vs. Creighton Prediction

Creighton enters this game as a heavy favorite, and for good reason. They’ve been one of the more consistent teams in the Big East, excelling on both ends of the floor. They already handled DePaul earlier this season, winning by a comfortable margin, and there’s little reason to believe this game will be any different.

DePaul has struggled against stronger competition all year, and that trend should continue against a superior Creighton squad. Ryan Kalkbrenner should dominate the paint, and Creighton’s balanced attack will be too much for DePaul to handle. While DePaul pulled off an upset last week, this is a different challenge, and Creighton should take control early and cover.

DePaul vs. Creighton Pick

Betting Pick: Creighton -11.5 (-130) Get oddschecker+ right now for just $9.99 per month. Don't miss out on this first month deal!

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