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Akron vs. Arizona Prediction, Latest March Madness Odds, Betting Pick for First Round

Arizona is one of the best teams coming into March Madness, but they meet a red-hot Akron squad in the First Round. Will Arizona take care of business, or will Akron shock the world? Next Level Bets takes a look at this interesting Round of 64 matchup and gives his thoughts and pick in this Akron vs. Arizona March Madness First Round Prediction article.

Akron vs. Arizona Prediction, Latest March Madness Odds, Betting Pick for First Round

We’ve got a very good March Madness matchup tonight on our hands here, as red-hot Akron rolls into this game looking to pull off a major upset against a talented Arizona squad.

Arizona comes in as big favorites, but Akron’s recent form has been impressive. The underdogs will look to keep this game close and prove they belong on this stage.

Let’s dive in and find the best bet for this one.

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Akron vs. Arizona Odds

  • ML: Akron +830, Arizona -1000
  • Spread: Akron +14.5 (-110), Arizona -14.5 (-105)
  • Total: Over 166.5 (+104), Under 166.5 (-110)

Akron vs. Arizona Date, Time, and Where to Watch

Date: March 21, 2025 Time: 7:35 PM ET Where to Watch: ESPN

Click here for latest Akron vs. Arizona Odds

Akron vs. Arizona Prediction

Arizona has looked like a top-tier team all season, led by their star Caleb Love. When he’s in rhythm, he can take over games, score at all three levels, and be unguardable. But we’ve also seen him force tough shots and struggle with consistency at times. Despite that, Arizona’s depth, defense, and experience make them a dangerous team that’s capable of making a deep tournament run.

On the other side, Akron is coming in red-hot, playing some of their best basketball of the season. They’ve been lighting it up offensively, and their shooting is what makes them dangerous in a spot like this. They move the ball well, get quality looks, and have been efficient from deep—something that’s crucial when trying to cover a big spread.

While Arizona is the more talented team, the way Akron has been playing lately — combined with their ability to score in bunches — makes this spread too big to ignore. They’ve got the tools to keep it respectable, and if their shooters stay hot, they can absolutely cover this number.

Akron Zips vs. Arizona Wildcats Pick

Pick: Akron +15.5 (-135)

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