Max Holloway vs. Dustin Poirier Prediction, Betting Pick, Latest Odds for UFC 318
Max Holloway and Dustin Poirier are squaring off for one last time before the 36-year-old Poirier hangs up the gloves. Can Poirier win all three fights of the trilogy, or will Holloway finally get revenge in this tightly-contested rivalry. Jason Radowitz is siding with the ladder scenario, and explains why in his Holloway vs. Poirier 3 prediction and best bet for the UFC 318 main event in New Orleans.
Jason Radowitz - July 19, 2025, 6:30 PM EDT
5 Minute ReadMax Holloway vs. Dustin Poirier Prediction, Betting Pick, Latest Odds for UFC 318
It was a fun career for Dustin Poirier. However, he's set to hang it up after this weekend's main event against Max Holloway.
It'll be the third fight between these two legends. Max Holloway made his debut in 2012 against Poirier and was submitted. However, they rematched in 2019, with Poirier winning a five-round decision for the interim lightweight title.
This is a matchup between two fan favorites with a rich history in the UFC. Ultimately, Holloway is transitioning from the featherweight division to the lightweight division after his latest defeat to featherweight champion Ilia Topuria. We'll see if he can handle the weight increase against Poirier.
Here are our picks, predictions, and odds for the UFC 318 main event between Max Holloway vs. Dustin Poirier.
Get your first month of oddschecker+ right now for just $0.99. Don't miss out on this exciting UFC deal!
Max Holloway vs. Dustin Poirier Odds
- Moneyline: Holloway (-130), Poirier (+110)
Max Holloway vs. Dustin Poirier Date, Time, and Where to Watch
- Date: Saturday, July 19, 2025
- Time: 10:00 PM ET (Main Card)
- Where to Watch: ESPN+ PPV
Click here for complete Holloway vs. Poirier odds
Max Holloway vs. Dustin Poirier Prediction
While Dustin Poirier is set to retire, Max Holloway is fighting for another title run in the lightweight division.
Of course, Holloway has more to gain at UFC 318. He'll easily have more motivation to win this fight. It's hard to know how much Poirier really put into his training, knowing this is the finale.
Holloway will be relentless. He'll dictate the pace and typically feeds off the fans' booing him. Since this fight is in Louisiana for Poirier's farewell, Poirier will likely have most of the fanbase on his side.
On the other hand, Poirier has more power, a bigger build, and more experience. In addition, as stated previously, he'll have the fan base on his side and should also benefit from that well. But some of these things can weigh on him. He's been worn down. It's why he's set to retire. His power might not be as good. His body may no longer be able to withstand the impact of a five-round fight.
Poirier has defeated Holloway twice in his career. But it's hard to beat somebody three times, especially when it's someone like Holloway.
Holloway did a lot of reflecting and thinks he knows what he did wrong in those first two fights. It'll be fun to think about how Poirier will face Holloway in his first and last fights. But I simply don't think he'll be able to hold up against one of the baddest men in the UFC in Holloway.
I'll back Holloway at -130.
Max Holloway vs. Dustin Poirier Pick
- Pick: Max Holloway (-130) Click here for complete Holloway vs. Poirier odds
MMA ODDS & PICKS
Affiliate Disclosure.
We are not a gambling or betting operator, but we receive a commission from these companies when we advertise their brands and refer customers to them (affiliate marketing). We provide information, odds information and links to websites of these companies. Some of the information made available on our site may be positioned as a result of a commission paid to us by a third party. We do not take or place bets/transactions and any information on Our Products is provided for entertainment purposes only.
