Leon Edwards vs. Carlos Prates Prediction, Betting Pick, Latest UFC 322 Odds
Leon Edwards is hoping to avoid a third-straight loss at UFC 322 at Madison Square Garden vs. Carlos Prates. Can he bounce back as as a slight underdog on Saturday night? Let's check out this Leon Edwards vs. Carlos Prates prediction for UFC 322.
Peter Alexis - November 15, 2025, 8:30 PM EST
5 Minute ReadLeon Edwards vs. Carlos Prates Prediction, Betting Pick, Latest UFC 322 Odds
UFC 322 arrives at Madison Square Garden on Saturday night, bringing a stacked main card to one of the most iconic combat sports venues in the world. The action begins at 10 p.m. ET, and one of the most intriguing matchups features former welterweight champion Leon Edwards looking to reclaim momentum against rising contender Carlos Prates. With both fighters carrying very different trajectories into this event, this bout could determine the future of the welterweight title picture.
Edwards enters as a rare underdog at +142, a surprising price for a fighter who once rattled off 12 straight wins before dropping his last two, including his most recent defeat in March. Now 33 and feeling the pressure of a late career crossroads, Edwards cannot afford a third straight setback. Prates, sitting at -168, is viewed by oddsmakers as the fresher and more dynamic fighter, but Edwards brings championship experience that could reshape this fight if he performs at his best.
Looking for advanced AI predictions and props to enhance your UFC betting? Try out oddschecker+ now on this limited time 7-day free trial!
Leon Edwards vs. Carlos Prates Odds
- Moneyline: Edwards (+142), Prates (-168)
Leon Edwards vs. Carlos Prates Date, Time, and Where to Watch
- Date: Saturday, November 15, 2025
- Time: 10:00 PM ET (Main Card Start)
- Where to Watch: ESPN+
Click here for complete Edwards vs. Prates odds
Leon Edwards vs. Carlos Prates Prediction
Prates is favored for a reason. His striking tempo and precision have overwhelmed opponents throughout his UFC rise, and his style poses real challenges for Edwards, who thrives on measured pressure and counter opportunities. Prates will look to force a faster pace, control range, and avoid the long stretches of inactivity that Edwards can create when he settles into his rhythm. If Prates keeps this fight at distance and dictates movement, he will justify his favorite status.
Still, Edwards remains one of the most well rounded welterweights in the sport. Even in defeat, his defensive skill, footwork, and high fight IQ have kept him competitive deep into championship level bouts. His jab, ability to switch stance, and strong clinch control give him multiple avenues to slow the fight down and frustrate aggressive opponents. The key for Edwards will be managing exchanges and avoiding extended firefights where Prates has a power edge.
Another major factor is experience. Edwards has been in with elite competition for nearly a decade, while this is Prates' biggest stage to date. At Madison Square Garden, in a co-headlining spotlight, pressure can flip the script quickly. Edwards has shown repeatedly that he can adapt mid fight, win late rounds, and seize opportunities when opponents fade or overcommit. If this bout becomes a tactical battle rather than a pure striking showcase, Edwards has a real chance to pull the upset.
Leon Edwards vs. Carlos Prates Pick
- Pick: Leon Edwards Moneyline +142 Click here to get the best odds at DraftKings Sportsbook
The line feels a bit wide for a fighter of Edwards' caliber. His experience, durability, and ability to turn a fast paced fight into a slow and technical one give him clear paths to victory. In a three round setting with his back against the wall, this is a spot where the underdog offers real value.
MMA ODDS & PICKS
Affiliate Disclosure.
We are not a gambling or betting operator, but we receive a commission from these companies when we advertise their brands and refer customers to them (affiliate marketing). We provide information, odds information and links to websites of these companies. Some of the information made available on our site may be positioned as a result of a commission paid to us by a third party. We do not take or place bets/transactions and any information on Our Products is provided for entertainment purposes only.
