Arman Tsarukyan vs. Mauricio Ruffy Prediction, Betting Pick, Latest UFC 331 Odds for September 19th
Arman Tsarukyan meets Mauricio Ruffy in a five-round lightweight co-main event with major title implications. Can Ruffy keep the fight standing long enough to impose his dangerous striking game? Check out this Arman Tsarukyan vs. Mauricio Ruffy prediction and best bet for Saturday, September 19.
Peter Alexis - September 19, 2026, 7:45 PM EDT
4 Minute ReadArman Tsarukyan vs. Mauricio Ruffy Prediction: Will Tsarukyan Earn KO in UFC 331 Co-Main Event?
Arman Tsarukyan returns against Mauricio Ruffy at UFC 331, with their five-round contest listed for approximately 10:45 p.m. Eastern on Paramount+. Tsarukyan is a -310 favorite, while Ruffy enters at +250.
Tsarukyan brings a five-fight winning streak into the matchup, most recently submitting Dan Hooker. Ruffy has responded to his loss against Benoit Saint Denis with stoppage victories over Rafael Fiziev and Michael Chandler, giving the underdog considerable momentum of his own.
Arman Tsarukyan vs. Mauricio Ruffy Odds
- Moneyline: Tsarukyan (-300), Ruffy (+250)
Arman Tsarukyan vs. Mauricio Ruffy Date, Time, and Where to Watch
- Date: Saturday, September 19th, 2026
- Time: 10:45 PM ET (Estimated Fight Time)
- Where to Watch: Paramount+
Click here for complete Arman Tsarukyan vs. Mauricio Ruffy odds
Arman Tsarukyan vs. Mauricio Ruffy Prediction
Ruffy’s striking makes prolonged exchanges at distance an unnecessary gamble for Tsarukyan. The favorite’s strongest approach is to combine his offense with takedown attempts, forcing Ruffy to account for level changes rather than freely setting his feet and building combinations.
Repeated wrestling exchanges could produce either of the outcomes covered by the selected double chance. Tsarukyan can pursue damaging ground strikes if he establishes dominant position, or build a decision through effective offense and sustained positional advantages across five rounds.
Ruffy’s ability to defend initial attempts will be important, but a first sprawl does not necessarily end the wrestling exchange. Tsarukyan can continue working along the fence and force repeated defensive efforts. That could gradually reduce the energy Ruffy has available for his most dangerous striking sequences.
The significant drawback is the excluded submission. Tsarukyan just finished Hooker that way, and Ruffy’s defeat against Saint Denis demonstrated the danger of losing position against a strong grappler. This wager deliberately accepts that risk in exchange for a considerably better price than the moneyline.
Arman Tsarukyan vs. Mauricio Ruffy Pick
- Pick: Arman Tsarukyan by KO or Decision Double Chance (-110) Check out these best odds at DraftKings Sportsbook
Tsarukyan is the selection to win through a striking stoppage or on the scorecards. The preferred script involves patient wrestling, damaging top offense and enough control of the exchanges to limit Ruffy’s knockout opportunities. A Tsarukyan submission would lose this bet.
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