Louisville vs. Notre Dame Prediction, Pick Against the Spread, Latest Odds
The Notre Dame Fighting Irish will host the Louisville Cardinals on Saturday afternoon in South Bend. Can Riley Leonard and the Fighting Irish continue to rebuild their playoff resume with a ranked win? Matt McCuen brings us his prediction and pick against the spread for Louisville vs. Notre Dame.
Matt McCuen - September 28, 2024, 9:30 AM EDT
5 minLouisville vs. Notre Dame Prediction, Pick Against the Spread, Latest Odds
The Louisville Cardinals and the Notre Dame Fighting Irish will meet from South Bend on Saturday afternoon.
Today's game is crucial for both teams who want to keep their playoff hopes alive. Louisville enters the contest with a perfect 3-0 record.
After reaching the ACC Championship a year ago, many believed the Cardinals would take a step back this season. So far, it's been good for Jeff Brohm's squad in four weeks.
The Cardinals' most notable win came last weekend when they took down Georgia Tech 31-19. The win moved Louisville up the rankings to 15th in the nation.
Louisville vs. Notre Dame Start Time, Where To Watch, Odds
- Date: Saturday, September 28, 2024
- Game Time: 3:30 p.m. ET
- Where to Watch: NBC, Peacock
Louisville vs. Notre Dame Odds
- Spread: Louisville +6.5 (-110), Notre Dame -6.5 (-110)
- Total Odds: O 46.5 (-110), U 46.5 (-110)
- Moneyline Odds: Louisville (+200), Notre Dame (-250)
Louisville vs. Notre Dame Prediction
Senior Tyler Shough leads the offense, throwing for 850 yards, eight touchdowns, and zero interceptions.
Freshman Issac Brown has been the top option in the Cardinals running game, rushing for 173 yards and one touchdown.
Ja’Corey Brooks has been the favorite target for the Cardinal's offense. Brooks has racked up 297 yards and two touchdowns.
Louisville ranks 24th on defense, allowing opponents 16.4 points per game.
Notre Dame begins the contest with a 3-1 record. One more loss will likely end the Irish hopes of playing in the college football playoffs.
Marcus Freeman’s squad got the season off to a perfect start as they entered Kyle Field and took down the Texas A&M Aggies. The Irish could not follow the win up, as they lost at home to Northern Illinois as a 28-point favorite.
Notre Dame has answered back with back-to-back wins over Purdue and Miami, Ohio. The Irish have outscored their opponents 94-10 over the last two weeks.
Riley Leonard leads the offense with 587 passing yards, one touchdown, and two interceptions.
St. Louis native Jeremiyah Love leads the ground game with 339 yards and four touchdowns.
Clemson transfer Beaux Collins has been the top target, racking up 176 yards and one touchdown.
The Notre Dame defense ranks 7th in the nation, allowing opponents 9.8 points.
Louisville vs. Notre Dame Pick
The Irish defense will be the X-factor in this game.
After a month, we see Notre Dame is a top-tier defense in college football.
The Cardinals have not been tested this season, and will get exposed by this Irish team today.
The Irish offense is due for a strong performance, which we will see today at home.
Pick: Notre Dame -6.5 -110 Click here to see which sportsbook has the best odds
College Football Odds
