South Dakota vs. Iowa State Prediction, Betting Pick, Latest CFB Odds for Saturday, August 30th
The South Dakota Coyotes will visit the No. 22 Iowa State Cyclones on Saturday afternoon with a chance to play spoiler after ISU's big win in Ireland. Can Aidan Bouman and the Yotes take advantage in this Week 1 letdown spot on FOX? McBets is expecting a scrappy performance, and explains why in his South Dakota vs. Iowa State prediction and best bet for Saturday, August 30th.
McBets - August 30, 2025, 9:30 AM EDT
5 Minute ReadSouth Dakota vs. Iowa State Prediction, Betting Pick, Latest CFB Odds for Saturday, August 30th
Week 1 rolls on, and this one has sneaky upset potential. Iowa State is coming off a dramatic Week 0 win in Dublin over Kansas State, but now they return home for what looks like a classic “letdown spot” against a dangerous FCS opponent—the South Dakota Coyotes.
This isn’t just any FCS program. South Dakota is fresh off an 11-3 season, a semifinal run in the FCS playoffs, and a share of the Missouri Valley title. They were balanced on both sides of the ball last year and bring back plenty of firepower. Can they pull a stunner against the ranked Cyclones today? Let's take a look at the complete South Dakota vs. Iowa State odds and prediction for Saturday, August 30th.
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South Dakota vs. Iowa State Odds
South Dakota vs. Iowa State Date, Time, and Where to Watch
- Date: Saturday, August 30, 2025
- Time: 2:30 PM ET
- Where to Watch: FOX
Click here for complete South Dakota vs. Iowa State odds
South Dakota vs. Iowa State Prediction
Quarterback Aidan Bouman is the name to know. He’s a former Iowa State backup who transferred to USD and lit it up last year—2,958 yards, 19 TDs, only 4 picks. He knows this Cyclone program inside and out, and he’ll be extra motivated stepping back into Ames. Pair him with a Coyotes offense that averaged 35.8 points per game (7th in FCS) and nearly 437 yards per game (9th in FCS), and you’ve got a unit more than capable of scoring points against a defense that just got back from a physical trip overseas.
Yes, the Cyclones are 1-0, but let’s be real—they were fortunate to escape Dublin with a 24–21 win over Kansas State. Travel fatigue is real, and asking a young offense to come back six days later and cover more than two touchdowns feels like a tall order. QB Rocco Becht is still developing chemistry with new receivers after losing his top two wideouts to the NFL, and Iowa State has historically played down to FCS competition in early-season games.
Defensively, Matt Campbell’s group is always tough, but the line is inflated here because oddsmakers love hanging big numbers on FBS vs. FCS matchups. The truth is, South Dakota is a top-tier FCS team with better talent than the spread suggests.
South Dakota vs. Iowa State Pick
- 1.5 Unit Pick: South Dakota +15.5 (-110) Click here to get the best South Dakota odds at DraftKings Sportsbook
South Dakota is well-coached, balanced, and hungry to prove they belong. Bouman gives them a QB who won’t be rattled, and the Coyotes’ physical style should allow them to hang tough for four quarters. Iowa State probably wins, but this feels more like a 10-point game than a blowout. The Coyotes are live to keep this one close in Ames. Take the points and ride with the dog.
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