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Sunday's game between the Indianapolis Colts (0-1-1) and the Kansas City Chiefs (2-0) will be played at Lucas Oil Stadium and will kick off at 1 p.m. ET. Come get this massive same-game parlay for Week 3 of the NFL.

Indianapolis Colts vs. Kansas City Chiefs Same-Game Parlay: Riding With JuJu Smith-Schuster in Week 3

Colts vs. Chiefs Start Time, Where to Watch, and Odds

  • Date: September 25, 2022
  • Start Time: 1:00 pm ET
  • Where to Watch: ABC

Click here for Chiefs vs. Colts odds

The Kansas City Chiefs defeated the Los Angeles Chargers 27-24 on Thursday night to secure a thrilling divisional victory. The Chiefs' Patrick Mahomes threw for 235 yards and two touchdowns, and the team's Clyde Edwards-Helaire rushed for 74 yards and caught 44 on 12 touches for a total of 118 yards. The biggest moment of the game was rookie CB Jaylen Watson's 99-yard interception return for a touchdown, which gave Kansas City the lead in the fourth quarter.

Following their tie in Week 1, the Colts had a poor performance in which they scored zero points last week. Due to the absence of receivers Michael Pittman Jr. and Alec Pierce due to injuries, Indy fell to Jacksonville 24-0, as Colts QB Matt Ryan struggled to establish any sort of momentum once again. Ryan threw three interceptions, and standout RB Jonathan Taylor only managed 54 rushing yards on nine attempts.

Let’s take a closer look at how things might play out when the two meet Sunday.

Indianapolis Colts vs. Kansas City Chiefs Same-Game Parlay Picks

Kansas City Chiefs -5.5 (-110)

With just one takeover on the season, this Colts defense hasn’t been talked about as much because of how bad the offense is doing; but it’s suspect, to say the least. Allowing 44 points in their first two games against the bottom half of the league offenses, the Colts will now be asked to contain one of the best in the league.

When Mahomes brings his Chiefs to town, he’ll be doing so with a unit already in the top 10 in total yards (#5), passing yards (#6), and points scored (#3). With no shortage of weapons to choose from, look for Mahomes to have himself a day as the Chiefs roll in this one. 

Anytime Touchdown Scorer -Clyde Edwards-Helaire (+140)

This selection follows our handicap above, but I think we see Edwards-Helaire find pay dirt on Sunday. So far through two games, he ranks #4 in the league with 7.7 yards per game and 116 total rushing yards on the season. And still without a touchdown on the ground. 

I think the Colts will give him plenty of lanes to run through, and Edwards-Helaire finally finds pay dirt come Sunday afternoon. 

Anytime Touchdown Scorer - JuJu Smith-Schuster (+180)

Speaking of not yet finding the end zone, the Chief’s WR1 has yet to find it through two games. Despite being WR1 and leading the team with 90 yards on nine receptions, JuJu has yet to find the end zone which I don’t think lasts much longer. 

Look for an emphasis from Mahomes that gets him in on Sunday.

Indianapolis Colts vs. Kansas City Chiefs Same-Game Parlay Picks

Same Game Parlay Odds: +750 (Bet $100 to win $750)

  • Chiefs -5.5 (-110)
  • Anytime TD -Clyde Edwards-Helaire (+140)
  • Anytime TD - JuJu Smith-Schuster (+180)

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Article Author


Johnny has been covering the sports betting markets and handicapping games for the better part of the past decade. Along the way, he has written for publications such as All-In Magazine, Blitz Predict, FantasyPros, Betting Pros, Sportsbook Review, and most recently, OddsChecker. In addition to giving out picks on Twitter, Johnny is the host of the podcast The Daily Sports Bet -- a 10 minute or less listen with actionable insights and no fluff or BS. Starting the podcast in June, he closed out 2021 up 26 units with a winning percentage of 55%.


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