Kansas City Chiefs vs. Tennessee Titans Prediction, Pick, Odds: Will The Chiefs Stop Derrick Henry on SNF?

The Tennessee Titans vs. the Kansas City Chiefs will meet up from Arrow Head Stadium for an AFC showdown in prime time. Now I am not sure who made this a prime-time game, but here we are.

The one good thing is that both of these teams enter play as the leaders in their respective divisions. The Titans represent a record of 5-2 on the season, while the Chiefs have matched that record of 5-2. Now, if you look at these teams' records, you may say that this looks like a good game. The books, however, are not anticipating a close one. Kansas City comes in as one of the largest prime-time favorites of the year, as they are a 12.5-point favorite.

Chiefs vs. Titans Start Time, Where to Watch, and Odds

• Date: November 6, 2022
• Game Time: 8:20 pm ET
• Where to Watch: NBC

Click here for the Chiefs vs. Titans odds

Kansas City Chiefs vs. Tennessee Titans Prediction

The Chiefs have not skipped a beat this season and once again appear to be a Super Bowl contender. They are led by one of the best players in the league in Patrick Mahomes, and they have weapons all over the field. Their defense has stepped up this year and has looked like a legitimate defense for the first two months of the year.

The Titans may be without starting QB Ryan Tannehill tonight. Nothing has officially been announced, but Tannehill did miss last week's game against the Houston Texans. That forced rookie quarterback Malik Willis into action, and he played well enough to get the road win. The team is high on Willis, and they believe that he can be their QB of the future. Willis may have to come in tonight and play in a challenging road environment. 

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I am turning to a prop tonight. Hold your breath on this prop because it will make us sweat and not be easy. I am taking the under of Derrick Henry tonight. Henry has rushed for 100-plus yards in his last four games, including rushing for 219 yards last week against the Texans.

Tonight we see his prop set at 88.5, and I am all over the under here. This should be a good spot for the under, as I see the Titans playing most of this game in a negative game script. I do not think that they will be able to run the ball in the second half. The only way for them to keep pace tonight will be by throwing the football. Kansas City also happens to have a great rushing defense ranking third in the league, allowing 92 rushing yards per game. 

Chiefs vs. Titans Pick

• Derrick Henry Under 87.5 rushing yards -115 Click here for the best odds, available at FanDuel