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Matt McCuen was on fire yesterday for the NFL, going 11-1 and hitting his same-game parlay for SNF. Join in on all the fun with Matt and tail his +400 same-game parlay for the Monday Night Football matchup between the Cardinals vs 49ers.

Monday Night Football Arizona Cardinals vs. San Francisco 49ers: Smash This +400 Same-Game Parlay

We just went 11-1 in the NFL yesterday and cashed our +480 SGP, so I am feeling great coming into tonight’s slate. I figured since we are so hot and just hit a same-game parlay that it would be fun to smash another same-game parlay tonight. The San Francisco 49ers vs. the Arizona Cardinals will clash for Mexico City for what should be a fun matchup.

Want to tail this same-game parlay with Matt? Click here to claim over $5,000 worth of sports betting bonuses to use on Monday Night Football game between the Cardinals vs 49ers!

Cardinals vs. 49ers Start Time, Where to Watch, and Odds

  • Date: November 21, 2022
  • Game Time: 8:15 pm ET
  • Where to Watch: ESPN

Click here for Cardinals vs. 49ers odds

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Cardinals vs. 49ers Prediction

San Fran is a team that a lot of people believe can be a Super Bowl contender. They have one of the best defenses in the NFL and represent one of the best rushing offenses in football. Arizona has had a rough season, and if they can not pull off an upset win tonight, their season will likely be over. They are expected to be led by Colt McCoy tonight as Kyler Murray continues to deal with injuries. The 49ers enter play tonight as a ten-point favorite. 

Cardinals vs. 49ers Same-Game Parlay

Leg 1

The first leg of this winner will be Arizona +10. I think the Cardinals play with a spirited effort tonight and can stay in this game. Colt McCoy is a guy who typically does not make bad mistakes, and I think he will keep them on schedule tonight.

Leg 2

The second leg will be James Conner over 14.5 receiving yards. I like McCoy to play the check-down game tonight against a defense that is tough to beat over the top.

Leg 3

The third and final leg will be Christian McCaffery anytime touchdown. The 49ers love to feature CMC, and I think that they use him a lot in this spot tonight. Let’s stay hot and cash in another! 

Cardinals vs. 49ers Same-Game Parlay Picks @+400 Best odds available at DraftKings (click here)

  • Leg 1: Arizona Cardinals +10.5 
  • Leg 2: James Conner Over 14.5 rec yards 
  • Leg 3: Christian McCaffery Anytime TD
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Article Author


Matt McCuen is a native of Delco, PA. He has been working in the sports gambling industry and creating content for the last few years. He is an expert in numerous different sports, including the NFL, NBA, MLB, NHL, and collegiate sports. You can follow Matt on Twitter at @DeadPresPicks.


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