
Cincinnati Bengals vs. San Francisco 49ers Prediction, Pick Against the Spread, and Latest Odds
The Cincinnati Bengals and the San Francisco 49ers will clash from San Francisco on Sunday afternoon for a highly anticipated affair. How will this game play out? Matt McCuen breaks it all down.
Matt McCuen - October 29, 2023, 10:41 AM EDT
5 minCincinnati Bengals vs. San Francisco 49ers Prediction, Pick Against the Spread, and Latest Odds
The Cincinnati Bengals and the San Francisco 49ers will clash from San Francisco on Sunday afternoon for a highly anticipated affair.
Bengals vs. 49ers Date, Time, and Where to Watch
- Date: October 29, 2023
- Game Time: 4:25 pm ET
- Where to Watch: CBS
Bengals vs. 49ers Odds
- Spread: Bengals +5 (-105), 49ers -5 (-110)
- Total Odds: O 43.5 (-109), U 43.5 (-110)
- Moneyline Odds: Bengals (+195), 49ers (-218)
Cincinnati Bengals vs. San Francisco 49ers Prediction
The Bengals enter play with a record of 3-3. Cincinnati has won two consecutive games and is coming off a bye week.
Joe Burrow leads this Bengals offense. Burrow inked a contract right before the season, making him the highest-paid quarterback in football at the time. Burrow struggled with injuries early but has looked much healthier in the last two weeks.
Joe Mixon has been the top back for the Bengals. Mixon has rushed for a team-high 366 yards and one touchdown.
Ja’Marr Chase has been the favorite target of Burrow. Chase has racked up 566 yards and three touchdowns.
Cincinnati ranks 17th in football in scoring defense.
San Francisco will begin play with a 5-2 record. The 49ers have lost two consecutive games, including a Monday Night Football loss to the Vikings.
Brock Purdy leads the 49ers offense. Purdy was questionable with a concussion but cleared protocols and will suit up today.
Christian McCaffery inked his name in the NFL history books a week ago when he rushed for a touchdown in 16 consecutive games. CMC is -220 to score a touchdown today.
Former Boise State standout Brandon Aiyuk is the top option in the passing game. He leads the team with 511 yards.
The 49ers defense ranks third in points allowed per game (15.9).
Cincinnati Bengals vs. San Francisco 49ers Pick
After two consecutive losses, this is a good spot to back the 49ers.
The game line has jumped from -3 to -5.5 as it continues to move in the direction of the 49ers.
The X Factor will be their defense, which has not played great in the last two weeks but will bounce back strong today.
The Bengals are a below-average defense that the 49ers will be able to put up points against.
Pick: San Francisco 49ers 1H -2.5 -110 Click here to see which sportsbook has the best odds
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