San Francisco 49ers vs. Jacksonville Jaguars Prediction, Pick Against the Spread, and Latest Odds
The San Francisco 49ers and Jacksonville Jaguars meet in NFL Week 10. Who has the edge? Matt McCuen shares his San Francisco 49ers vs. Jacksonville Jaguars Prediction, pick, and the latest odds.
Matt McCuen - November 12, 2023, 9:31 AM EST
5 minSan Francisco 49ers vs. Jacksonville Jaguars Prediction, Pick Against the Spread, and Latest Odds
The San Francisco 49ers and the Jacksonville Jaguars will meet up from the Sunshine State on Sunday afternoon.
49ers vs. Jaguars Date, Time, and Where to Watch
- Date: November 12, 2023
- Game Time: 1:00 pm ET
- Where to Watch: FOX
49ers vs. Jaguars Odds
- Spread: 49ers -3 (-110), Jaguars +3 (+102)
- Total Odds: O 45 (-108), U 45 (-110)
- Moneyline Odds: 49ers (-168), Jaguars (+155)
San Francisco 49ers vs. Jacksonville Jaguars Prediction
The 49ers will begin play on Sunday with a record of 5-3. The 49ers have lost three consecutive games.
San Fransisco got off to a 5-0 start, but things have been downhill since.
Brock Purdy leads this San Francisco offense. Purdy has thrown for 2,033 yards, 12 touchdowns, and five interceptions.
Running back Christian McCaffery leads the San Francisco backfield. McCaffrey has rushed for a team-best 652 yards, paired with nine rushing touchdowns.
McCaffery has scored in every game this season.
Wide receiver Brandon Ayiuk has been the team's top option in the passing game. Ayiuk has racked up a team-high 620 yards.
The 49ers defense ranks 4th in football allowing opponents 17.5 points per game.
Jacksonville enters play as one of the hottest teams in football.
The Jags have won five consecutive games. Jacksonville sits atop of the AFC South.
Former number one overall pick Trevor Lawrence leads the Jags offense. Lawrence has thrown for 1,935 yards, nine touchdowns, and four interceptions.
Running back Travis Etienne Jr. leads the Jags backfield. Etienne has rushed for 583 yards and seven touchdowns.
Wide receiver Christian Kirk has been the favorite target of Lawrence. Kirk has racked up 520 yards and three touchdowns.
The Jags defense ranks eighth in football in points allowed per game (19.5).
San Francisco 49ers vs. Jacksonville Jaguars Pick
This is the perfect buy-low spot for the 49ers.
Yes, they have struggled as of late, but after a bye week, I expect a strong effort from the 49ers.
San Fransisco will return Deebo Samuel, which is a massive boost for this offense.
Additionally, tackle Trent Williams may play in this game.
The Jags rank 30th against the pass. The 49ers will use their playmakers in the passing game, which will be the difference this week.
Pick: San Francisco 49ers -3 -110 Click here to see which sportsbook has the best odds
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NFL Odds
