49ers vs. Seahawks Prediction, Pick, Odds: Do Brock Purdy, 49ers Have The Edge In This Thanksgiving Showdown?
The NFL is closing out the triple header tomorrow with an NFC West matchup between the San Francisco 49ers and Seattle Seahawks. Do Brock Purdy and the 49ers have the edge in this Thanksgiving showdown? Jason Radowitz answers.
Jason Radowitz - November 22, 2023, 10:20 AM EST
5 min49ers vs. Seahawks Prediction, Pick, Odds: Is Seattle Healthy Enough For This Thanksgiving Showdown?
The NFL is closing out the triple header on Thanksgiving with an NFC West matchup between the San Francisco 49ers and Seattle Seahawks.
The 49ers and Seahawks are fighting for the top spot in the NFC West. No matter what happens in this game, both teams are in a solid position to make the playoffs.
San Francisco returned from their bye week a couple of weeks ago and has won two games since. Before the bye, the Niners fell apart and lost three straight.
Meanwhile, the Seahawks have won three of their last five. But with questions surrounding the offense's health, Seattle could be in trouble.
Can the 49ers hand Seattle its fifth loss of the season on the road?
Here are our picks, predictions, and odds for Thursday's game between the San Francisco 49ers vs. Seattle Seahawks.
49ers vs. Seahawks Date, Time, and Where to Watch
- Date: November 23, 2023
- Game Time: 8:20 pm ET
- Where to Watch: NBC
49ers vs. Seahawks Odds
- Spread: 49ers -6.5 (-110), Seahawks +6.5 (-110)
- Total Odds: O/U 43 (-110)
- Moneyline Odds: 49ers (-285), Seahawks (+230)
49ers vs. Seahawks Injury Report
49ers
Questionable: OL Aaron Banks (Toe), WR Ray-Ray McCloud III (Ribs), Shemar Jean-Charles (Shoulder), DT Javon Hargrave (Thumb), OT Spencer Burford (Knee)
Out: S Talanoa Hufanga (Knee)
Seahawks
Questionable: WR Drake Young (Abdominal), WR Jake Bobo (Shoulder), QB Geno Smith (Elbow), RB Kenneth Walker III (Oblique)
Out: S Jerrick Reed II (Knee)
49ers vs. Seahawks Prediction
The San Francisco 49ers looked like the best team in the NFL through the season's first month. But they hit a wall before their bye week, losing three straight games from October 15 to October 29.
Since that bye week, the 49ers have regrouped. They've won back-to-back games against the Jaguars and Buccaneers with a combined score of 61-17.
I would say that the 49ers are back.
The Niners have averaged over 250 yards passing with 132.7 yards on the ground per game. Brock Purdy has only thrown five interceptions this season. When he's not turning the ball over, the 49ers are almost impossible to beat.
Meanwhile, Christian McCaffrey has a touchdown in all but one game this year for the 49ers. He's one of the best running backs in the league because he's super versatile. McCaffrey has 825 yards and nine touchdowns on the ground. But he's also got 364 yards receiving with another five touchdowns.
This season, Seattle has really struggled to convert on tackles. They're missing a ton of opportunities. This is where McCaffrey and the rest of the 49ers can really get to the Seahawks.
Seattle has allowed 112.6 yards per game on the ground. That's not entirely bad. But the 49ers have a good enough run game to beat up the Seahawks on the ground.
On the other hand, the Seahawks have Geno Smith and Kenneth Walker III listed as questionable. It's probably more likely Smith plays over Walker at this point.
If Smith couldn't go due to a tricep injury, the Seahawks would roll with Drew Lock, who has only completed four passes on 12 attempts this year. However, he still has experience and isn't a horrible backup.
In place of Kenneth Walker III would be Zach Charbonnet. He's added 4.9 yards per carry, which is better than Walker III's 4.1 yards per carry. Charbonnet has seen more carries recently, anyway. He'll be a factor in this game with or without Walker III.
The 49ers have held teams to 81.4 yards on the ground. But they've allowed some big plays in the run game. They're suspectable to the big play in the ground game.
Seattle will want to limit turnovers and try to find success running the football. It'll likely be a struggle.
Therefore, let's take the Under 43 in this matchup.
San Francisco 49ers vs. Seattle Seahawks Pick
- Under 43 -110 is currently the best odds. Click here to see which sportsbook has the best odds
Win a $50 Gift Card on NFL Sunday Football
Think you know what's going to happen in various games on NFL Sunday this week? Answer the pick questions below for your chance to win a $50 Amazon gift card!
NFL Odds
