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San Francisco 49ers vs. Philadelphia Eagles Prediction: Will Brock Purdy, Niners Get Revenge in NFC Rematch?

The San Francisco 49ers are looking for revenge on the road, and Brock Purdy wants a second crack at the Eagles after getting injured last year. Can the Niners get a crucial victory as they fight for playoff seeding in the NFC? Krabs breaks down 49ers vs. Eagles and gives us his best bet.

Krabs - December 3, 2023, 11:40 AM EST

5 min

San Francisco 49ers vs. Philadelphia Eagles Prediction: Will Brock Purdy, Niners Get Revenge in NFC Rematch?

After the best game of the college football season between Alabama and Georgia on Saturday, we move to the NFL. The 49ers and Eagles face-off in Philadelphia, with the winner getting crowned as the best team in the NFC. Which powerhouse will earn a victory on Sunday afternoon, and most importantly, which team will cover?

49ers vs. Eagles Date, Time, and Where to Watch

  • Date: December 3, 2023
  • Game Time: 4:25 pm ET
  • Where to Watch: FOX

49ers vs. Eagles Odds

  • Spread: 49ers -3 (-110), Eagles +3 (-110)
  • Total Odds: O/U 47.5 (-110)
  • Moneyline Odds: 49ers (-150), Eagles (+125)

San Francisco 49ers vs. Philadelphia Eagles Prediction

The Eagles might be 10-1 atop the NFC with a league-best 7-2-2 ATS record, but that doesn’t mean they are the better team. Just look at the spread. Oddsmakers clearly think San Francisco is the better team, making them a three-point favorite on the road in Philly. That’s some serious respect for a second year QB matched up with Jalen Hurts, the favorite to win the MVP.

Brock Purdy and the 49ers are looking to get revenge against the team that knocked them out of the playoffs last season. They’ve also had three extra days to prepare for this matchup, a huge advantage for Kyle Shanahan. They’ll have a solid matchup against a struggling Eagles’ secondary that’s gotten bailed out by their quarterback numerous times this year.

The Eagles defense isn’t bad, but their pass defense is. They give up the fourth-most yards per game through the air this season behind Washington, Tampa Bay and the Chargers. Those aren’t defenses you want to be grouped with. Brock Purdy has regained his confidence with solid performances against Jacksonville, Tampa Bay and Seattle in recent weeks. He should dominate this struggling Eagles secondary.

This 49ers team has been unstoppable since trading for Chase Young. Their defense is elite; it doesn’t matter how good the Eagles offensive line is, they will struggle against Nick Bosa, Chase Young and the best defensive line in the league.

Was anyone else shocked to see the 49ers open up as favorites in this game? I certainly was, and I was even more surprised when I saw them move up to a three-point favorite. This spread is extremely telling. The Eagles pulled off some miracle wins in recent weeks, but the party ends this afternoon. San Francisco’s defense is on another level right now, and the Eagles’ secondary is in for a rough afternoon.

San Francisco 49ers vs. Philadelphia Eagles Pick

Pick: SF -3 (-110) Click here to see which sportsbook has the best odds

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