DraftKings Pick6 Rams vs. 49ers: Four DK Pick 6 Picks for Thursday Night Football

Tonight, we will cook up a DraftKings Pick 6 entry for Thursday Night Football.

We have been red-hot on Pick 6 entries this season, and will cash another one tonight. Be sure to check out the Pick 6 app on DraftKings.

Before we dive into this Pick 6 entry, let's take a closer look at this Rams vs. 49ers matchup as both teams fight for playoff positioning with only a few weeks left in the regular season.

Get oddschecker+ right now for just $9.99 per month. Don't miss out on this December deal!

Los Angeles Rams vs. San Francisco 49ers Date, Time, and Where To Watch

• Date: December 12, 2024
• Time: 8:15 pm ET
• Where To Watch: Amazon Prime Video

Los Angeles Rams vs. San Francisco 49ers Prediction

The San Francisco 49ers will host the Los Angeles Rams for an NFC West showdown.

The 49ers have posted a record of 6-7. That record has placed the 49ers dead last in the NFC West. San Francisco entered the season as the betting favorite to win the NFC West. The good news for the Niners is that with a win tonight, they will be tied for second place in the division.

Injuries have played a major role in slowing this team down. The 49ers have struggled to stay healthy on both sides of the football. San Francisco played one of their best games of the season last weekend against the Chicago Bears, rolling to a 38-13 win. The 38-point performance was the 49ers best offensive outing of the season.

Los Angeles is coming off a massive win of their own. Matthew Stafford and company took down the Buffalo Bills in a 44-42 shootout. The win was the most impressive victory of the year for Sean McVay's team.

Tonight, the Rams can take over first place in the West. After a sluggish 1-4 start to the season, the Rams have been one of the best teams in football over the past two months.

Los Angeles won the first meeting between these two teams 27-24 in Week 3. The 49ers come into this game as a three-point favorite. The total for this matchup is 48.5.

Sign up for DraftKings Pick6 now!

Los Angeles Rams vs. San Francisco 49ers DraftKings Pick6 Picks

Leg 1: Matthew Stafford Over 250.5 Passing Yards

Stafford has been one of the best in the game this season in terms of passing yards.

The former first-overall pick ranks 5th in passing yards.

The game script will bode well for Stafford tonight.

2. Deebo Samuel Over 50.5 Receiving Yards

Samuel has been outspoken about his frustrations with the 49ers offense.

I anticipate the 49ers making it a point of emphasis to get the football into the hands of their top playmaker.

Samuel will deliver a breakout game tonight.

3. Cooper Kupp Over 64.5 Receiving Yards

Kupp has been Stafford's top target for years and will step up with a big-time performance tonight.

The 49ers' secondary has struggled this season and does not match up well against Kupp.

Lastly, the game script will favor this prop, as the Rams will play most of this game from behind.

Leg 4: Jauan Jennings Under 5.5 Receptions

Jennings has enjoyed the best year of his career.

However, this prop is set too high tonight.

San Fran will play with the lead, which means Jennings will have fewer opportunities in the passing game.