
Rams vs. 49ers Prediction, Pick Against the Spread, Latest Odds for Thursday Night Football
The San Francisco 49ers will try to get back on the right track with a huge NFC West divisional win on Thursday Night Football. Can Brock Purdy lead the banged-up 49ers to a win over the Los Angeles Rams tonight? Matt McCuen is targeting the home favorite in this Rams vs. 49ers clash on TNF.
Matt McCuen - December 12, 2024, 10:55 AM EST
4 minRams vs. 49ers Prediction, Pick Against the Spread, Latest Odds for Thursday Night Football
The Los Angeles Rams and the San Francisco 49ers will meet for an NFC West showdown on Thursday Night Football. Levi's Stadium will be the site for this highly anticipated matchup.
The Rams begin this game with a record of 7-6. Sean McVay's team has been one of the best teams in football over the last two months. LA is coming off its biggest win of the season, a victory over the Buffalo Bills on Sunday. The Rams outlasted the Bills in a 44-42 shootout, putting the Rams in a playoff position.
Tonight is a key game for Los Angeles who can get to two games over .500 for the first time this season. Los Angeles has won back-to-back games and three of its last four. The Rams defeated the 49ers 27-24 earlier in the season in Los Angeles.
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Los Angeles Rams vs. San Francisco 49ers Odds
Los Angeles Rams vs. San Francisco 49ers Date, Time, and Where To Watch
- Date: December 12, 2024
- Time: 8:15 pm ET
- Where To Watch: Amazon Prime Video
Los Angeles Rams vs. San Francisco 49ers Prediction
Veteran Matthew Stafford has thrown for 3,303 yards, 19 touchdowns, and seven interceptions. Former Notre Dame standout Kyren Williams leads the ground game with 1,013 yards and 12 touchdowns. Puka Nacua has been the top option in the passing game with 708 yards and three touchdowns. The Rams have allowed 25.5 points per game, ranking 24th in the NFL.
San Francisco begins this game with a record of 6-7. That record has placed the Niners in last place in the NFC West. San Francisco's season has been highly disappointing after entering the season as the betting favorite to win the NFC.
The Niners reached the Super Bowl a season ago, and came into the year with most of their roster returning. Unfortunately for the Niners, injuries have slowed this team down. Most notably, running back Christian McCaffrey is out for the rest of the season. CMC has played in just four games this year.
Additionally, backup running back Jordan Mason will miss the remainder of the season. Mason rushed for a team-best 789 yards. The 49ers are coming off a commanding win over the Chicago Bears, and will attempt to stay hot at home tonight.
Brock Purdy leads the offense with 3,032 yards, 15 touchdowns, and eight interceptions. Former Louisville running back Isaac Guerendo is expected to start tonight. Guerendo has rushed for 324 yards and four touchdowns so far. Tight end George Kittle has been the top option in the passing game with 800 yards and eight touchdowns. The Niners defense ranks 21st in points allowed per game (23.7).
Los Angeles Rams vs. San Francisco 49ers Pick
- Pick: San Francisco 49ers -3 +100 Get oddschecker+ right now for just $9.99 per month. Don't miss out on this December deal!
We are getting great value on the Niners at home tonight.
After a big-time performance last weekend, the 49ers will carry that momentum into this game.
The Rams are in a tough position tonight, playing on the road in a short week.
San Francisco will control the tempo of this game and earn a season series split with their rivals tonight.










