49ers vs. Rams Same Game Parlay: Targeting Mac Jones, Puka Nacua Props on Thursday Night Football
The banged-up 49ers are heading to take on NFC West rival Los Angeles Rams on Thursday Night Football, but do they stand a chance? Mac Jones will be up against the odds on TNF when he faces a Rams defense with nearly no weapons. McBets knows the script and is targeting two players in his 49ers vs. Rams same game parlay for Thursday, October 2nd.
McBets - October 2, 2025, 1:00 PM EDT
4 Minute Read49ers vs. Rams Same Game Parlay: Does Mac Jones Stand a Chance Against Staunch Rams Defense?
Thursday night brings a fascinating NFC West clash between the 49ers and Rams, and it sets up perfectly for bettors eyeing the same-game parlay market. On one side, Puka Nacua continues to be the centerpiece of Los Angeles’ passing attack. Coming off a monster outing with 13 catches for 170 yards and a touchdown against the Colts, he’s proven himself as one of the most consistent high-volume receivers in football. With Matthew Stafford locked in on him as the go-to option, Nacua’s receptions and yardage props will be popular targets again this week.
Across the field, the 49ers’ situation looks far shakier. Mac Jones will make his third start of the season in place of the injured Brock Purdy, but he’ll be without his two main targets in Ricky Pearsall and Jauan Jennings, who are both sidelined. That leaves major questions about where San Francisco’s passing game production will come from, and whether Jones can move the ball against a Rams defense that will key heavily on Christian McCaffrey. The combination of Nacua’s steady volume and San Francisco’s depleted air attack creates an intriguing parlay setup — one where backing the Rams’ passing game and fading the 49ers’ could go hand-in-hand.
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49ers vs. Rams Date, Time, and Where to Watch
- Date: Thursday, October 2, 2025
- Time: 8:15 PM ET
- How to Watch: Prime Video
49ers vs. Rams Odds
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49ers vs. Rams Same Game Parlay
Leg 1: Puka Nacua 7+ Receptions
Through four games this season, Nacua has been a target magnet — averaging 10.5 catches per game and clearing the 7+ receptions mark every single week. His lone matchup against San Francisco last season tells the same story, where he covered this exact line.
The 49ers’ defense, while stout, has been surprisingly vulnerable to opposing WR1s, allowing each one they’ve faced this season to hit their receptions number. With Matthew Stafford locked in on his top option, Nacua should once again be peppered with targets.
Leg 2: Mac Jones Under 1.5 Passing Touchdowns
On the other side, things look bleak for Mac Jones and the Patriots’ passing attack. Jones has thrown for fewer than two touchdowns in five of his last six road games, and this week he’s dealing with a depleted offense. Missing key weapons like Jauan Jennings, Ricky Pearsall, George Kittle, and Brandon Aiyuk makes life even harder.
To make matters worse, the Rams defense has been stingy against the pass, allowing the 7th-fewest passing TDs in the league. The only quarterback to throw for more than one score against them this season? Jalen Hurts. Jones is no Hurts — and the odds of him bucking that trend are slim.
49ers vs. Rams Same Game Parlay (+101)Click here to get these best odds on FanDuel Sportsbook
- Leg 1: Puka Nacua 7+ Receptions
- Leg 2: Mac Jones Under 1.5 Passing Touchdowns
Put it together, and you’ve got a sharp two-leg parlay at +101 odds that combines Nacua’s high-volume role with Jones’ red-zone struggles. It’s a classic case of riding a star player while fading an offense in shambles — and it could cash big this weekend.
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