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Cole Caufield Canadiens Goal

Canadiens vs. Sabres Prediction, Betting Pick, Latest Stanley Cup Playoff Odds for Game 1

The Montreal Canadiens and Buffalo Sabres will square off in the second round of the Stanley Cup Playoffs on Wednesday night. Can the Canadiens maintain their momentum from the last series and surprise the Sabres in Game 1? Let's take a look at this Canadiens vs. Sabres prediction and best betting pick for Wednesday, May 6th's Game 1.

OC Staff - May 6, 2026, 5:00 PM EDT

3 Minute Read

Canadiens vs. Sabres Prediction: Can Nick Suzuki, Canadiens Carry Momentum into Second Round Series?

The Canadiens arrive in Buffalo with one of the strangest and grittiest playoff wins in franchise history behind them. Montreal survived Game 7 against Tampa Bay despite being outshot 29-9, with Nick Suzuki scoring early, Alex Newhook finding the winner in the third period, and Jakub Dobes carrying the pressure in a 2-1 road win that pushed the Canadiens into the second round. It was the fewest shots ever recorded by a winning team in a Stanley Cup playoff game, and it summed up the identity Montreal needed to eliminate the Lightning.

Buffalo enters Game 1 with its own breakthrough story after eliminating Boston in six games for the franchise’s first playoff series win in 19 years. The Sabres won all three road games in Boston, closed the series with a 4-1 Game 6 win, and now return home with the top seed, home ice, and a young core that has finally pushed the franchise back into the second round.

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Canadiens vs. Sabres Date, Time, and Where to Watch

  • Date: Wednesday, May 6, 2026
  • Time: 7:00 PM ET
  • How to Watch: TNT, HBOMax

Canadiens vs. Sabres Odds

Click here for the latest Canadiens vs. Sabres Game 1 Odds

Canadiens vs. Sabres Prediction

Montreal’s first-round profile was not always pretty, but it was built for playoff survival. The Canadiens went 3-1 on the road against Tampa Bay, won Game 1 in overtime, absorbed the Lightning’s pressure throughout the series, and still found a way to win the two biggest games away from home. That matters in this matchup because Buffalo will bring pace, skill, and a building that has waited nearly two decades for a second-round playoff game. Montreal already proved it can handle hostile ice and win without needing a clean offensive script.

Buffalo’s case is more explosive. The Sabres got balanced scoring against Boston, with Alex Tuch, Zach Benson, Josh Norris, Tage Thompson, Rasmus Dahlin, and the blue line all playing important roles across the series. Their Game 6 closeout was controlled, physical, and mature, especially for a team carrying the emotional weight of ending a 19-year drought between playoff series wins. The Sabres are no longer just a promising group. They are a legitimate second-round threat with speed, depth, and confidence.

The pressure point in Game 1 is whether Montreal can generate enough offense after surviving Tampa Bay with almost none in Game 7. Nine shots and no second-period shots are not a repeatable formula, even with Dobes playing at a high level. The Canadiens need more from Suzuki, Cole Caufield, Juraj Slafkovsky, and their transition game if they want to turn this into more than a grind-it-out road underdog spot. Buffalo’s pace should force Montreal to defend in layers, but it should also create chances the other way if the Canadiens can break cleanly through the neutral zone.

Canadiens vs. Sabres Best Bet

The best bet is Nick Suzuki over 2.5 shots on target at +115. Suzuki cleared this number in only three of his last 10 games, but the matchup and role point toward a more aggressive Game 1. He is Montreal’s offensive tone-setter, he scored in the Game 7 win over Tampa Bay, and the Canadiens cannot afford another low-volume attack against a Buffalo team with more scoring depth than Boston showed in Round 1. The FairPlay projection gives Suzuki a 62.42% chance to go over 2.5 shots against a 46.51% implied probability, creating 34.2% EV at plus money. That makes the shot prop the cleaner angle than trying to pick a side in what should be a tight second-round opener.

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