Tottenham vs Atletico Madrid Prediction, Betting Pick, Latest Champions League Round of 16 Odds
The UEFA Champions League Round of 16 second leg sees Tottenham host Atletico Madrid at the Tottenham Hotspur Stadium on Wednesday, 18th March 2026, with kick-off scheduled for 8:00 PM GMT. The hosts face a monumental task, needing to overturn a significant deficit after a comprehensive 5-2 defeat in the first leg in Madrid.
OC Staff - March 18, 2026, 1:30 PM EDT
3 Minute ReadTottenham vs Atletico Madrid: Lineups, Team News and Prediction
The UEFA Champions League Round of 16 second leg sees Tottenham host Atletico Madrid at the Tottenham Hotspur Stadium on Wednesday, 18th March 2026, with kick-off scheduled for 8:00 PM GMT. The hosts face a monumental task, needing to overturn a significant deficit after a comprehensive 5-2 defeat in the first leg in Madrid.
Tottenham vs Atletico Form
Tottenham come into this crucial European fixture having secured a 1-1 draw against Liverpool in their most recent outing in the Premier League. This result followed a heavy 5-2 loss to Atletico in the first leg of this very competition. Over their last six matches across all competitions, the North London side has endured a challenging run, with their only victory coming against Fulham (2-1) in early March. They have also suffered defeats to Crystal Palace (3-1), Arsenal (4-1), and Newcastle (2-1) in the Premier League, alongside the first-leg thrashing in the Champions League.
Atletico, meanwhile, arrive in London with their confidence high, having beaten Getafe 1-0 in their last domestic league game. This victory is part of a strong run of form for the Spanish giants, who have won four of their last six matches. Their recent Champions League encounter saw them dispatch Club Brugge 4-1 at home, while in LaLiga, they secured a 3-2 win over Real Sociedad and a 1-0 away victory against Real Oviedo. Their only blip in this period was a 3-0 Copa del Rey defeat to Barcelona. The visitors have also shown a tendency for high-scoring games, with their last Champions League match seeing them score 5 goals.
Tottenham vs Atletico Head to Head
The most recent encounter between these two sides was the first leg of this very tie, which saw Atletico Madrid claim a dominant 5-2 victory over Tottenham at home. Prior to that, their only other recorded meeting was in the 2016 Champions Cup, where Atletico emerged 1-0 winners against Tottenham. Atletico have thus won both previous meetings against the London club.
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Tottenham vs. Atletico Madrid Odds
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Tottenham vs Atletico Probable Lineups
Tottenham (4-3-3):
- Goalkeeper: Vicario
- Defenders: Spence (DL), Danso (DC), Dragusin (DC), Porro (DR)
- Midfielders: Gallagher (MC), Sarr (DM), Gray (MC)
- Forwards: Tel (FL), Solanke (FC), Muani (FR)
Atletico (4-4-2):
- Goalkeeper: Musso
- Defenders: Ruggeri (DL), Hancko (DC), Le Normand (DC), Pubill (DR)
- Midfielders: Lookman (ML), Llorente (MC), Cardoso (MC), Simeone (MR)
- Forwards: Alvarez (FC), Griezmann (FC)
Tottenham vs Atletico Team News
Tottenham are grappling with a substantial injury list ahead of this critical fixture. The hosts will be without Ben Davies, Will Odobert, Lucas Bergvall, and Mohammed Kudus, all sidelined due to injury. Furthermore, Richarlison is suspended, adding to the attacking woes. Dominic Solanke is expected to lead the line, having been a bright spot in their European campaign.
Atletico Madrid have fewer injury concerns, with Rodrigo Mendoza confirmed as an absentee. Goalkeeper Jan Oblak is also unavailable for the clash. Despite these absences, the visitors are expected to field a strong side, with Julián Álvarez and Antoine Griezmann leading the attack.
Tottenham vs Atletico Match Facts
- Atletico Madrid have scored at least 2 goals in their last 3 matches (Champions League).
- Tottenham have won their last 4 home matches (Champions League).
- Tottenham have kept a clean sheet in their last 4 home matches (Champions League).
- Atletico Madrid have scored at least 2 goals in 5 of their last 6 matches (all competitions).
- Tottenham are winless in their last 8 matches (all competitions).
Prediction: Tottenham 2-2 Atletico
Tottenham face an almost insurmountable challenge to progress in the Champions League, needing to overturn a three-goal deficit against a defensively astute Atletico Madrid side. Historically, advancing after losing a first leg by three or more goals is extremely rare in this competition.
Despite their recent struggles in overall form, the Lilywhites have been a different beast at home in the Champions League this season. They have won all four of their home matches in the tournament without conceding a single goal, scoring ten times in the process. This strong home defensive record, combined with their attacking intent (demonstrated by their 'Attack down the wings' and 'Create many scoring chances' styles), suggests they will push hard for goals. However, their weakness in defending against long shots and counter-attacks could be exploited by Atletico's clinical finishing and attacking depth, led by the in-form Julián Álvarez and Antoine Griezmann.
Atletico, with their 'Counter-attack threat' and 'Clinical finishing', are well-equipped to manage the game and exploit any spaces left by Tottenham's desperate attacking efforts. Their impressive attacking numbers, with 29 goals in the Champions League this season, highlight their potency. While Tottenham will likely score at home, Atletico's strong offensive capabilities and the comfortable lead from the first leg mean they are unlikely to be overwhelmed. A draw seems a plausible outcome, with Tottenham pushing but Atletico holding firm and perhaps finding a goal or two on the break.
Best Bet: Both Teams to Score – Yes Check out the best odds on Caesars Sportsbook
Given Tottenham's exceptional scoring record at home in the Champions League this season (10 goals in 4 home matches) and their need to attack, combined with Atletico's potent offense (29 goals in the competition, 'Clinical finishing' strength), both teams finding the net appears highly probable. While Tottenham have kept clean sheets in their home Champions League games so far, the pressure of a 5-2 aggregate deficit will force them to open up, potentially exposing their defensive weaknesses. Atletico's ability to score in 5 of their last 6 matches further supports this.
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