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Burnley vs Man City Prediction, Betting Pick, Latest Premier League Odds for Wednesday, April 22

Rock-bottom Burnley host title-chasing Manchester City in a crucial Premier League encounter at Turf Moor on Wednesday 22nd April, with kick-off scheduled for 19:00 BST. The Clarets, currently languishing in 19th position, are desperate for points to stave off relegation, while second-placed City are looking to close the gap on the league leaders and maintain their impressive run of form.

OC Staff - April 22, 2026, 8:00 AM EDT

3 Minute Read

Burnley vs Man City: Lineups, Team News and Prediction

Rock-bottom Burnley host title-chasing Manchester City in a crucial Premier League encounter at Turf Moor on Wednesday 22nd April, with kick-off scheduled for 19:00 BST. The Clarets, currently languishing in 19th position, are desperate for points to stave off relegation, while second-placed City are looking to close the gap on the league leaders and maintain their impressive run of form.

Burnley vs Man City Form

Burnley's recent form paints a grim picture, with the home side losing their last Premier League outing 4-1 away to Nottingham Forest. Across their last six league fixtures, Vincent Kompany's side sits at the very bottom of the form table, managing just one draw and suffering five defeats. They have lost five of their last six Premier League matches and have alarmingly conceded at least two goals in five of those six games, highlighting significant defensive frailties.

In stark contrast, Manchester City arrive in formidable shape, having secured a 2-1 victory over Arsenal in their most recent league fixture. The reigning champions are the league's top-performing side over the last six matches, boasting four wins and two draws, remaining undefeated during this period. City are currently on a remarkable run of ten Premier League matches without defeat and have scored at least two goals in eight of their last ten league outings.

Burnley vs Man City Head to Head

The historical record between these two clubs heavily favours the visitors. The most recent clash saw Manchester City emerge as dominant 5-1 winners over Burnley in September of the current season. This result continues a trend of complete dominance, with City winning all of the last six meetings between the sides. In fact, Manchester City have won their last 14 matches against Burnley across all competitions. Their attacking prowess against the Clarets is evident, having scored at least two goals in their last 11 encounters. Furthermore, City have been winning at both half-time and full-time in their last five away matches against Burnley and have kept a clean sheet in their last four trips to Turf Moor.

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Burnley vs. Man City Odds

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Burnley vs Man City Probable Lineups

Burnley (4-2-3-1):

Goalkeeper: M. Dúbravka

Defenders: Q. Hartman (DL), M. Estève (DC), H. Ekdal (DC), K. Walker (DR)

Midfielders: J. Ward-Prowse (DM), Florentino (DM), J. Anthony (AML), L. Ugochukwu (AMC), M. Edwards (AMR)

Forward: Z. Flemming (FC)

Man City (4-2-3-1):

Goalkeeper: G. Donnarumma

Defenders: N. O'Reilly (DL), M. Guéhi (DC), A. Khusanov (DC), M. Nunes (DR)

Midfielders: Rodri (DM), B. Silva (DM), J. Doku (AML), R. Cherki (AMC), A. Semenyo (AMR)

Forward: E. Haaland (FC)

Burnley vs Man City Team News

Burnley are facing a significant injury crisis for this daunting fixture. They are set to be without five first-team players, with Beyer, Cullen, Roberts, Mejbri, and Amdouni all sidelined. Josh Cullen has been ruled out for the remainder of the season with a long-term knee problem, while Hannibal Mejbri and Zeki Amdouni are not expected to return to action until next month. These absences will severely test the depth of the Clarets' squad.

Manchester City, on the other hand, have fewer injury concerns. While Josko Gvardiol is still a few weeks away from returning from his long-term injury, there is a possibility that Ruben Dias could make a return from a thigh issue, though he remains doubtful. Pep Guardiola is likely to name a strong starting XI, similar to the one that faced Arsenal.

Burnley vs Man City Match Facts

  • Burnley have lost 5 of their last 6 matches in Premier League.
  • Burnley have seen over 2.5 goals in their last 4 matches against Man City in all competitions.
  • Burnley have conceded at least 2 goals in 5 of their last 6 matches in Premier League.
  • Man City have won their last 14 matches against Burnley in all competitions.
  • Man City have scored at least 2 goals in their last 11 matches against Burnley in all competitions.
  • Man City have been winning at both half-time and full-time in their last 5 away matches against Burnley in all competitions.
  • Man City have kept a clean sheet in their last 4 away matches against Burnley in all competitions.
  • Man City have scored at least 2 goals in 8 of their last 10 matches in Premier League.
  • Man City are undefeated in their last 10 matches in Premier League.

Prediction: Burnley 0-3 Man City

Burnley's recent defeat at Nottingham Forest has pushed them to the brink of relegation, making their return to the Championship seem inevitable. The Clarets have a dismal record against Manchester City, having lost their last 14 encounters and conceding at least twice in nearly all of them. Their defensive weaknesses, particularly against attacks down the wings, through balls, and counter-attacks, play directly into Manchester City's hands. City's strengths lie in their clinical finishing, ability to create chances through individual skill and through balls, and their dominance in possession in the opposition's half. With City hitting peak form and aiming to go top of the Premier League, they will be looking to improve their goal difference against a Burnley side with the league's worst defence. Expect a comfortable and dominant performance from the visitors.

Best Bet: Man City to Win and Over 2.5 Goals

Given Manchester City's overwhelming head-to-head record against Burnley, their current impressive scoring form (at least two goals in 8 of their last 10 league matches and 11 of their last 14 against Burnley), and Burnley's defensive struggles (conceding at least two goals in five of their last six league games), a strong betting angle emerges. The combination of a dominant City victory with goals flowing seems highly probable. The fact that City have been winning at both half-time and full-time in their last five away matches against Burnley further underscores their superiority.

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