Como vs RB Leipzig Lineups, Prediction, Betting Picks & Champions League Odds for Thursday, September 10th
Get the latest Como vs RB Leipzig prediction, lineups, and betting picks for this Champions League game. Explore top odds and Same Game Parlay insights.
Grayson Parker - September 10, 2026, 12:00 PM EDT
7 minutesComo vs RB Leipzig Game Preview
Competition | UEFA Champions League |
|---|---|
Game Date | September 10, 2026 |
Game Time | 3:00 PM ET / 12:00 PM PT |
Venue (City, Stadium) | Giuseppe Sinigaglia |
The Como vs RB Leipzig prediction centers on a milestone night at the Sinigaglia, where Como make their first-ever appearance in European club competition against a familiar Champions League name in RB Leipzig.
Como reached this stage by finishing fourth in Serie A last season, and boss Cesc Fàbregas makes his Champions League coaching debut having logged 104 appearances in the competition as a player.
RB Leipzig are back in the Champions League for an eighth campaign after missing European soccer entirely in 2025/26, arriving as the more battle-tested side despite recent defensive worries.
There is no head-to-head history here, which only sharpens the intrigue: a debutant riding real momentum against a German side still searching for stability at this level.
Como vs RB Leipzig Recent Results
Como enter on an eight-game unbeaten run, winning five and drawing one of their last six while scoring 13 and conceding just four. That balance underlines a stubborn, well-drilled group. Nico Paz and Martin Baturina supply the creative spark between the lines, with Tasos Douvikas leading the line for Fàbregas's confident side.
RB Leipzig have been far messier, taking three wins and three defeats across their last six games. They have scored 14 but leaked 12 over that stretch, and have conceded in each of their last 18 European Cup outings. Christopher Nkunku remains the focal point after the visitors scored in 11 straight games across all competitions.
Como vs RB Leipzig Lineups & Team News
Injuries & Suspensions
Como: Mauro Vigorito (Ineligible), Edoardo Goldaniga (Ineligible), Maxence Caqueret (Ineligible), Jayden Addai (Ineligible), Willy Kambwala (Ineligible), Adrian Lahdo (Ineligible)
RB Leipzig: Rocco Reitz (Injured/out), Castello Lukeba (Injured/out), Brajan Gruda (Injured/out), Assan Ouédraogo (Injured/out), Rômulo (Injured/out), Viggo Gebel (Injured/out), Christoph Baumgartner (Injured/out), Leopold Zingerle (Ineligible), Abdoul Koné (Ineligible), Suleman Sani (Ineligible)
Como
Fàbregas is without six players, all ineligible, with Jayden Addai also recovering from an Achilles tendon rupture. Jean Butez should start behind a back four of Yan Couto, Jacobo Ramón, Trevoh Chalobah and Álex Valle. Lucas Da Cunha and Luis Milla anchor midfield, freeing Nico Paz and Martin Baturina to operate higher up. Assane Diao adds width with Tasos Douvikas up top, and Moise Kean offers real Champions League pedigree if called upon, having contributed five goals and one assist in six starts in the competition across his career.
RB Leipzig
Leipzig have a long absentee list, with three players ineligible and seven more, including Castello Lukeba, unavailable. Maarten Vandevoordt should continue in goal behind Ridle Baku, Willi Orbán, Maxime Estève and David Raum. Lukeba's absence thins the defense and leans more responsibility on Orbán to organize a back line that has struggled for clean sheets in Europe. Neil El Aynaoui, Ezechiel Banzuzi and Nicolas Seiwald should form the midfield, with Tidiam Gomis and Antonio Nusa behind Christopher Nkunku, who gives the visitors a proven link between midfield and attack.
Como vs RB Leipzig Predicted Lineup
Como
Formation: 4-2-3-1
Predicted Starting Lineup: Butez; Couto, Chalobah, Ramón, Valle; Milla, Da Cunha; Diao, Paz, Baturina; Douvikas
RB Leipzig
Formation: 4-3-2-1
Predicted Starting Lineup: Vandevoordt; Baku, Orbán, Estève, Raum; El Aynaoui, Banzuzi, Seiwald; Nusa, Gomis; Nkunku
Como vs RB Leipzig Key Stats & Game Facts
- RB Leipzig have conceded in each of their last 18 Champions League games, a defensive worry heading into this trip.
- Leipzig have lost four straight games away from home in the Champions League.
- The visitors have scored in 11 consecutive games across all competitions.
- Among teams to have played at least 50 Champions League games since 1992/93, Leipzig's fixtures average the most goals per game at 3.4.
- Leipzig lost seven of their eight league-phase games in the 2024/25 Champions League campaign.
Como vs RB Leipzig Prediction & Best Picks
Our Prediction
Our prediction leans toward the hosts. The model makes Como the home favorite at just over a 50% implied probability, and with Fàbregas's side riding an eight-game unbeaten run against a Leipzig group that has lost four in a row on the road in this competition, the projected 2-2 scoreline points to a competitive, entertaining night with the momentum firmly on Como's side.
Best Picks
Back 'No' in the Both Teams To Score market. The Both Teams To Score market is where the model finds its strongest value here. With Como owning the best defensive record in Serie A last season and Leipzig's attack needing to break down a disciplined defensive structure, the numbers tilt toward a one-sided scoring night.
Back Under 2.5 Goals in the Total Goals Over/Under market. A projected combined total of 2.47 goals sits just below the key line, making Under 2.5 Goals in the Total Goals Over/Under market an attractive option. Como's defensive organization should limit Leipzig's chances in what figures to be a measured, compact European opener.
Como vs RB Leipzig Same Game Parlay
Our Como vs RB Leipzig Same Game Parlay backs Como on the moneyline, Moise Kean to score anytime and both teams to find the net at the Sinigaglia.
Como on the moneyline makes sense with home advantage and the model's roughly 51% read on the hosts, who arrive unbeaten in eight and defensively solid.
Moise Kean anytime goalscorer taps into his Champions League pedigree, with five goals and one assist in six career starts in the competition if Fàbregas turns to him.
Both Teams To Score is backed by Leipzig conceding in each of their last 18 Champions League games while also scoring in 11 straight across all competitions.
Together these legs frame an open, high-value ticket that leans on Como's momentum at home while respecting Leipzig's attacking threat through Nkunku and company.
Right now, the best combined price on this three-leg SGP beats the shortest available elsewhere by a meaningful margin. Check below for the live comparison across books before placing.
Compare the sharpest prices across all books with Oddschecker's Same Game Parlay Comparison Tool before you lock in.
Same Game Parlay odds correct at time of publishing.
Como vs RB Leipzig Talking Points
This is a genuine fairy-tale opener. Como climbed from Serie D in 2018/19 all the way to the Champions League in 2026, becoming the 16th different Italian club to reach the competition. Their defensive foundation is the story: only 29 goals conceded across the 2025/26 Serie A campaign, the best record in the Italian top flight, and that same discipline carries into a Como vs RB Leipzig betting odds picture that favors a tight game. Leipzig, back after a year away from Europe, bring the bigger name and Nkunku's threat, but a defense that has leaked in 18 straight Champions League games and lost four on the trot on the road leaves plenty of doubt. If Fàbregas's side embrace the occasion and stay compact, the debutants have a real path to a statement result on home soil.
Como vs RB Leipzig Predictions FAQs
When is the Como vs RB Leipzig Champions League game?
The game takes place on Thursday, September 10, 2026, kicking off at 3:00 PM ET / 12:00 PM PT.
Where is Como vs RB Leipzig being played?
The game is being played at Giuseppe Sinigaglia.
Where can I watch Como vs RB Leipzig?
The game is scheduled to be broadcast live on TNT Sport 3 HD.
What are the predicted lineups for Como vs RB Leipzig?
Como are projected to line up in a 4-2-3-1 formation led by Tasos Douvikas in attack, while RB Leipzig are expected to start in a 4-3-2-1 formation with Christopher Nkunku leading the line.
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