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PSV vs Shakhtar Donetsk Lineups, Prediction, Betting Picks & Odds

PSV vs Shakhtar Donetsk Lineups, Prediction, Betting Picks & Champions League Odds for Thursday, September 10th

PSV vs Shakhtar Donetsk prediction, lineups, betting picks, and odds. Explore top analysis and Same Game Parlay insights for this big Champions League game.

PSV vs Shakhtar Donetsk Game Preview

Competition

UEFA Champions League

Game Date

September 10, 2026

Game Time

12:45 PM ET / 9:45 AM PT

Venue (City, Stadium)

Philips Stadion

PSV and Shakhtar Donetsk open their 2026/27 Champions League campaigns at the Philips Stadion, and our PSV vs Shakhtar Donetsk prediction leans toward the hosts in an open matchup.

This is PSV's 20th appearance in the competition proper, a new record for Dutch clubs. Peter Bosz's side arrive unbeaten in their last five games and are clear favorites at home.

Shakhtar also enter their 20th overall Champions League campaign, riding five straight away wins across all competitions, though their long-term travel record at this level remains a concern.

The clubs have met once before in Europe, PSV edging a 3-2 win in Eindhoven. Both carry attacking quality and defensive absences, so goals look likely in this opener.

PSV vs Shakhtar Donetsk Recent Results

PSV come into this one unbeaten in their last five games and look sharp going forward. Their European numbers were up last season, hitting 16 goals across eight Champions League games, their best scoring average in a single campaign since the competition rebranded. Ricardo Pepi is the man to watch, with six goals and three assists in the competition for PSV.

Shakhtar arrive on a five-game away winning streak across all competitions, a real momentum boost heading into Europe. Arda Turan's side reached the Conference League semifinals last season, and Alisson Santana was among their leading scorers in that run. Santana remains a direct threat from wide, though the step back up to Champions League level is a stiff test.

PSV vs Shakhtar Donetsk Lineups & Team News

Injuries & Suspensions

PSV: Alassane Pléa (Injured/out), Sam Lammers (Injured/out), Dennis Man (Injured/out), Kiliann Sildillia (Injured/out), Sami Ouaissa (Injured/out), Jerdy Schouten (Injured/out), Mauro Júnior (Suspended), Mikkel Bro Hansen (Ineligible)

Shakhtar Donetsk: Prosper Obah (Injured/out), Marlon (Injured/out), Kiril Fesyun (Injured/out), Alan Matturro (Injured/out), Eguinaldo (Injured/out), Pedrinho (Injured/out), Denys Tvardovskyi (Ineligible)

PSV

Peter Bosz has a long absentee list, with Alassane Pléa, Sam Lammers, Dennis Man, Kiliann Sildillia, Sami Ouaissa and Jerdy Schouten all unavailable, while Mauro Júnior is suspended. Matej Kovar should start in goal behind a back line of Sergiño Dest, Lutsharel Geertruida, Armando Obispo and Filip Kostic. Noah Fernandez and Kodai Sano are expected to anchor midfield, with Guus Til pushing forward and Ivan Perisic and Ruben van Bommel providing width around Pepi.

Shakhtar Donetsk

Arda Turan is without Prosper Obah, Marlon, Pedrinho, Kiril Fesyun, Alan Matturro and Eguinaldo, leaving the visitors short on options. Dmytro Riznyk should continue in goal behind Vinicius Tobias, Valeriy Bondar, Mykola Matvienko and Pedro Henrique. Matvienko's experience will be vital against Pepi. Marlon Gomes and Oleg Ocheretko should form the double pivot, with Alisson Santana, Isaque and Newerton operating behind Kaua Elias up top.

PSV vs Shakhtar Donetsk Predicted Lineup

PSV

Formation: 4-2-3-1

Predicted Starting Lineup: Kovar; Dest, Geertruida, Obispo, Kostic; Sano, Fernandez; Perisic, Til, van Bommel; Pepi

Shakhtar Donetsk

Formation: 4-2-3-1

Predicted Starting Lineup: Riznyk; Tobias, Bondar, Matvienko, Henrique; Ocheretko, Gomes; Santana, Isaque, Newerton; Elias

PSV vs Shakhtar Donetsk Key Stats & Game Facts

  • PSV have lost their opening Champions League game in each of their last five campaigns.
  • Shakhtar have won only two of their last 15 Champions League away games, losing 10.
  • Shakhtar have taken just one victory from six previous European trips to the Netherlands.
  • Ricardo Pepi has been directly involved in nine goals in the Champions League for PSV, scoring six and assisting three.
  • PSV scored 16 goals across eight Champions League games last season, their best scoring average in a single campaign since 1992/93.

PSV vs Shakhtar Donetsk Prediction & Best Picks

Our Prediction

Our prediction is a 2-1 PSV win. The hosts have the stronger home attacking threat and Ricardo Pepi's European efficiency gives them a clear route to three points, but Shakhtar's away momentum and both teams' defensive absences point to a game with goals at both ends. PSV vs Shakhtar Donetsk betting odds back the hosts as favorites, and we agree.

Best Picks

Ricardo Pepi to score anytime. This one sits in the Anytime Goalscorer market. Pepi spearheads the PSV attack with an outstanding Champions League record of six goals and three assists, and the numbers give him better than a coin-flip shot at finding the net here.

Ruben van Bommel to record over 1.5 tackles. This falls in the Total Tackles Over/Under market for the player. Van Bommel starts on the left flank in PSV's high-pressing 4-2-3-1, and with Shakhtar's full-backs pushing on, he projects strongly to make at least two tackles against their advancing wide players.

PSV vs Shakhtar Donetsk Same Game Parlay

Our PSV vs Shakhtar Donetsk Same Game Parlay picks lean into the home side controlling this opener, with PSV to win, Ricardo Pepi to score anytime and both teams to find the net.

PSV are clear favorites on the moneyline. Bosz's side are unbeaten in five and boast the stronger home attacking threat, making them the logical anchor leg for this parlay.

Pepi is the natural pick to score. His European return of six goals and three assists for PSV makes him the central attacking focal point and the most likely name on the scoresheet.

Both Teams To Score gets the nod given the defensive absences on both sides. Shakhtar carry a direct threat through Santana, so goals at both ends look a fair call.

The math stacks up too. Pepi's exceptional efficiency and PSV's home edge keep every leg pointing in the same direction, which is exactly what you want in a parlay.

Right now, the best combined price on this SGP is +290 across the board, with the short end sitting at +245. On a $10 stake, that spread in pricing translates to a $4 difference in potential profit from top to bottom.

Shop around for the sharpest SGP number before you place, and use Oddschecker's Same Game Parlay Comparison Tool to find where your parlay pays the most.

Same Game Parlay odds correct at time of publishing.

PSV vs Shakhtar Donetsk Talking Points

History is not on PSV's side when it comes to openers, as they have lost their Matchday 1 game in each of their last five Champions League campaigns, with their last opening-game win dating back to September 15, 2015 against Manchester United. The flip side is their firepower: PSV's previous 10 Champions League games have produced 44 goals, an average of 4.4 per game, and that attacking edge is a big reason we like the hosts here. Shakhtar's travel record is the counterweight, with just one away win in the Netherlands in European play, a 2-1 victory over Feyenoord on October 17, 2017. Add in the defensive absences on both sides and this shapes up as an open, high-scoring opener that plays right into PSV's hands.

PSV vs Shakhtar Donetsk Predictions FAQs

When is the PSV vs Shakhtar Donetsk Champions League game?

The Champions League game is scheduled to kick off at 12:45 PM ET / 9:45 AM PT on Thursday, September 10, 2026.

Where is PSV vs Shakhtar Donetsk being played?

The game will be played at Philips Stadion.

Where can I watch PSV vs Shakhtar Donetsk?

The game is scheduled to be broadcast live on TNT Sport 3 HD.

What is the score prediction for PSV vs Shakhtar Donetsk?

The predicted score for the game is a 2-1 victory for PSV over Shakhtar Donetsk.

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