Atletico Madrid vs Osasuna Lineups, Prediction, Betting Picks & Odds

Atletico Madrid vs Osasuna Game Preview

Atletico Madrid host Osasuna at the Riyadh Air Metropolitano on Wednesday, and this Atletico Madrid vs Osasuna prediction leans heavily toward the home side in a matchup they have long controlled.

Atletico return home clear favorites, having lost just once in LaLiga this campaign and banked 10 points from five games, though they already trail leaders Barcelona by five points.

Osasuna sit around mid-table after a promising start faded. Unbeaten through three games with two wins, the visitors have since lost two straight and arrive in a slump.

These teams have not played to a tie in 21 straight meetings, and Atletico have won 14 of their last 16 games against Osasuna in all competitions.

Atletico Madrid vs Osasuna Recent Results

Atletico have been sharp at the top end, with 3+ goals landing in each of their last four LaLiga outings and the scoresheet ticking over at a steady clip in LaLiga this season. Diego Simeone's side sit fifth in the standings and fifth in the form rankings, a dangerous attacking group leaning on wide play and set-piece threat.

Osasuna have cooled off after a bright opening, dropping two in a row to slide toward mid-table. Ranked 11th in both the standings and form, the visitors lean on Ante Budimir up top, who has found the net in four of his last five LaLiga appearances and stays busy winning fouls and firing shots.

Atletico Madrid vs Osasuna Lineups & Team News

Injuries & Suspensions

Atletico Madrid: Pablo Barrios (Injured/out), Julian Alvarez (Injured/doubtful), Alexander Sorloth (Injured/doubtful)

Osasuna: Jorge Herrando (Injured/out), Aimar Oroz (Injured/out), Moi Gomez (Injured/out), Valentin Rosier (Injured/doubtful)

Atletico Madrid

Pablo Barrios has picked up an injury and is a confirmed absentee for Atletico in this game. Julian Alvarez and Alexander Sorloth could also miss out, as the pair are doubts for the home side. That leaves the front line leaning on Giuliano Simeone and Ademola Lookman, with Alex Baena pulling the strings in midfield.

Osasuna

Valentin Rosier could miss out for the away side. He has been out for over a month and is a doubt for this game. Jorge Herrando, Aimar Oroz, and Moi Gomez are all unavailable through injury, thinning out the visitors' options ahead of a tough trip to Madrid.

Atletico Madrid vs Osasuna Predicted Lineup

Atletico Madrid

Formation: 3-5-2

Predicted Starting Lineup: Oblak; Hancko, Pubill, Romero; Llorente, Koke, Baena, Kang-In, Grimaldo; G. Simeone, Lookman

Osasuna

Formation: 4-2-3-1

Predicted Starting Lineup: Herrera; Osambela, Boyomo, Catena, Bretones; Torro, Moncayola; Castillo, Dubasin, Moro; Budimir

Atletico Madrid vs Osasuna Key Stats & Game Facts

• There have been 27+ shots taken in five of the last eight meetings between Atletico Madrid and Osasuna (LaLiga).
• Osasuna have received 2+ cards in five of their last seven games vs Atletico Madrid (LaLiga).
• Atletico Madrid have kept a clean sheet in seven of their last 10 games vs Osasuna (LaLiga).
• Osasuna have failed to score in seven of their last 10 games vs Atletico Madrid (LaLiga).
• Ante Budimir has attempted 2+ shots in seven of his last nine games vs Atletico Madrid (LaLiga).

Atletico Madrid vs Osasuna Prediction & Best Picks

Our Prediction

This one points firmly toward the hosts. Our prediction is a 2-1 Atletico Madrid win. Simeone's side are humming in attack, favored on the moneyline at -150 (Betfred), and they have owned this matchup, while Osasuna's slump and injury list make a road result a tall order. Expect the home firepower to tell, but Budimir keeps the visitors on the board.

Best Picks

David Hancko to record over 1.5 tackles in the match. This pick sits in the Player Tackles Over/Under market. Hancko is a nailed-on starting center back for Atletico, and with the underdogs likely chasing the game for long stretches, he should have plenty of defending to do throughout.

Ante Budimir to commit over 1.5 fouls in the match. This one lands in the Player Fouls Committed Over/Under market. Leading the line for the visiting underdogs against a stubborn Atletico defense, Budimir is the kind of physical lone striker who gets dragged into scrappy duels — exactly the situation that generates two or more fouls.

Atletico Madrid vs Osasuna Same Game Parlay

Our four-leg Same Game Parlay backs Kike Barja to be shown a card, Ante Budimir as an anytime goalscorer, over 1.5 total home goals for Atletico, and Alex Baena over 0.5 assists.

Kike Barja has picked up a card in four of his last five LaLiga outings, and a physical Osasuna side traveling as underdogs into a hard game makes another booking a live angle here.

Budimir has netted in four of his last five LaLiga games and stays active against Atletico, so backing him to find the net keeps our anytime goalscorer leg on solid ground.

Atletico's attack has been relentless on home soil, clearing 2+ goals in five of their last six LaLiga outings — over 1.5 home goals fits a side that consistently delivers at the Metropolitano.

Alex Baena is the primary creative playmaker for Atletico and has assisted in three of his last five apps vs Osasuna (LaLiga), making his over 0.5 assists a natural fit.

Right now, this Same Game Parlay returns a best price of +5000 and dips to as low as +3500 at other books. That's a difference in potential winnings of $150 from best to worst price.

Lock in the best value on your Same Game Parlay using Oddschecker's Exclusive Same Game Parlay Comparison Tool.

Same Game Parlay odds correct at time of publishing.

Atletico Madrid vs Osasuna Talking Points

The headline storyline is a mismatch of momentum. Atletico return home as heavy favorites, priced at -150 (William Hill) on the moneyline, riding an attack that has been consistently productive — the scoresheet has hit 3+ goals in each of Atletico's last four LaLiga outings. Captain Koke keeps adding to his legacy too, recently making his 746th official appearance for the club in a 3-0 league win against Real Sociedad, drawing level with Sir Bobby Charlton in eighth on the all-time European list for appearances at a single club. Osasuna, meanwhile, arrive in a two-game slide and undermanned, leaning on Ante Budimir to give them a foothold. History is stacked against the visitors, who have failed to score in seven of their last 10 games against Atletico (LaLiga). That said, value hunters will note Osasuna at +850 (AK Bets) has drawn strong expected-value flags, so a shock is not out of the question even if the numbers point one way.

Atletico Madrid vs Osasuna Predictions FAQs

When is the Atletico Madrid vs Osasuna Spanish Primera Division game?

The game kicks off on Wednesday, September 16, 2026, at 1:00 PM ET / 10:00 AM PT.

Where is Atletico Madrid vs Osasuna being played?

The game is being played at the Riyadh Air Metropolitano in Madrid.

Where can I watch Atletico Madrid vs Osasuna?

The game is scheduled for broadcast on Premier Sports and BeIn Sports.

What is the team news for Atletico Madrid vs Osasuna?

Atletico Madrid will be without injured midfielder Pablo Barrios, while Julian Alvarez and Alexander Sorloth are doubts. Osasuna are missing Jorge Herrando, Aimar Oroz, and Moi Gomez through injury, with Valentin Rosier also doubtful.

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