Fiorentina vs Napoli Lineups, Prediction, Betting Picks & Odds

Fiorentina vs Napoli Game Preview

Napoli travel to the Artemio Franchi as the favorites in a Serie A matchup that has produced goals every time these two have met lately. This one has that same feel.

Fiorentina have found some rhythm under new boss Paolo Vanoli, stringing back-to-back wins across Serie A and the Coppa Italia. They also lead the league in completed dribbles with 43.

Napoli sit on six points from four games after grinding out a 1-0 win over Bologna. Massimiliano Allegri has called this trip one of the most important games of the season.

The head-to-head tells a clear story. Napoli have won their last four games against Fiorentina in all competitions, and have scored at least 2 goals in their last 6 games against Fiorentina in all competitions.

Fiorentina vs Napoli Recent Results

Fiorentina have steadied things after a rocky opening, landing morale-boosting wins over Venezia in Serie A and local rivals Pisa in the cup. The attack is humming, with 10-plus shots on target in each of their last four Serie A games and 14-plus total shots in three straight. Mateo Pellegrino leads the line and has been in fine scoring form, netting in back-to-back Serie A outings from his last three.

Napoli are grinding results out, most recently a 1-0 win over Bologna that pushed them to six points from four games. Their front three is dangerous, with Rasmus Højlund on the scoresheet in a pair of his last three Serie A appearances and Kevin De Bruyne pulling the strings in midfield. This is a direct, disciplined side that knows how to close games out.

Fiorentina vs Napoli Lineups & Team News

Injuries & Suspensions

Fiorentina: Fabiano Parisi (Injured/out), Radu Dragusin (Injured/doubtful)

Napoli: Alessandro Buongiorno (Injured/out), Scott McTominay (Injured/out), Luca Marianucci (Injured/out), Alex Meret (Injured/out), Giovane (Injured/out), Alisson Santos (Injured/out), Andre-Frank Zambo Anguissa (Injured/doubtful)

Fiorentina

Vanoli looks set to stick with his 4-3-3, with David de Gea firmly established in goal. A makeshift back line will feature Joao Mario, Luca Ranieri, Marin Pongracic and Viery, as Radu Dragusin remains a major fitness doubt. Up top, Abdoulaye N'Jaye and Franco Mastantuono are slated to flank central striker Mateo Pellegrino, while left-back Fabiano Parisi is the sole long-term absentee.

Napoli

Napoli deploy their trademark 4-3-3, with Vanja Milinkovic-Savic getting the nod in goal following Alex Meret's injury. The back four is anchored by Amir Rrahmani and Rafa Marin at center back, flanked by Giovanni Di Lorenzo and Leonardo Spinazzola. Billy Gilmour, Stanislav Lobotka and Kevin De Bruyne dictate play, while Noa Lang and Matteo Politano provide width for Rasmus Højlund.

Fiorentina vs Napoli Predicted Lineup

Fiorentina

Formation: 4-3-3

Predicted Starting Lineup: De Gea; Viery, Ranieri, Pongracic, Joao Mario; Atta, Fagioli, Ndour; N'Jie, Pellegrino, Mastantuono

Napoli

Formation: 4-3-3

Predicted Starting Lineup: Milinkovic-Savic; Spinazzola, Marin, Rrahmani, Di Lorenzo; Gilmour, Lobotka, De Bruyne; Lang, Højlund, Politano

Fiorentina vs Napoli Key Stats & Game Facts

• Napoli have scored 2+ goals in 5 out of 5 games vs Fiorentina (Serie A).
• There have been 10+ shots on target in 4 of Fiorentina's last 4 games (Serie A).
• Rasmus Højlund has scored in 2 of their last 3 apps (Serie A).
• Joao Mario has won 2+ fouls in 3 of their last 3 games (Serie A).
• Rolando Mandragora has attempted 3+ shots in 3 of their last 3 games vs Napoli (Serie A).

Fiorentina vs Napoli Prediction & Best Picks

Our Prediction

Fiorentina have life under Vanoli, but Napoli have owned this matchup and carry the sharper cutting edge with Højlund and De Bruyne. Our prediction is a 2-1 Napoli win, with goals at both ends given the way these two attack.

Best Picks

Back Stanislav Lobotka to commit over 1.5 fouls in the Player Fouls market. Lobotka anchors the midfield in what shapes up as a scrappy, contested battle at the Artemio Franchi. He figures to be heavily involved in breaking up Fiorentina's transitions, and the Fiorentina vs Napoli betting odds reflect a midfield that rarely runs smoothly in this rivalry.

Back Marin Pongračić to record over 2.5 tackles in the Player Tackles market. With Fiorentina's makeshift back line staring down a potent Napoli attack led by Højlund and De Bruyne, Pongracic figures to be busy breaking up phases all afternoon. The implied probability from the sportsbook sits well below what his defensive workload in this kind of game would suggest, pointing to clear value in the Player Tackles market.

Fiorentina vs Napoli Same Game Parlay

Our four-leg Same Game Parlay leans into the goals: Mateo Pellegrino to score anytime, Napoli over 1.5 team goals, Lorenzo Lucca over 2.5 shots, and both teams to score.

Pellegrino is Fiorentina's go-to finisher and has been sharp recently, netting in a couple of his last three Serie A outings. Backing him anytime makes sense given this attack's tempo.

Napoli over 1.5 team goals is grounded in history: the Azzurri have scored at least 2 goals in their last 6 games against Fiorentina in all competitions.

Lorenzo Lucca over 2.5 shots is a smart add: he has cleared that mark in 3 of his last 5 games against Fiorentina (Serie A), per the head-to-head record.

Both teams to score rounds it out, landing in 5 of the last 6 meetings between these two (Serie A), with both attacks in decent touch right now.

At the time of writing, this Same Game Parlay pays a best price of +823 and is as short as +718 elsewhere. Shop around: that gap adds up to roughly $10 on a $10 stake from top to bottom.

Compare prices on this Fiorentina vs Napoli same game parlay picks parlay using Oddschecker's Same Game Parlay Comparison Tool to lock in the best number.

Same Game Parlay odds correct at time of publishing.

Fiorentina vs Napoli Talking Points

Vanoli has made no secret of the threat Napoli pose, calling Allegri a "winner" who exploits his team's strengths and admitting he is "in love with Kevin De Bruyne" for the way the Belgian reads space. He also stressed that preventative marking is essential to shut down Napoli's transitions, singling out Rasmus Højlund as the quickest striker in open play in Serie A. On the other side, Allegri has publicly challenged winger Noa Lang to raise his technical impact and spirit, saying the player "can and must give more considering his qualities." With Fiorentina's makeshift defense facing that pace and De Bruyne's vision, the visitors carry the sharper edge, and the numbers back a goal-heavy afternoon.

Fiorentina vs Napoli Predictions FAQs

When is the Fiorentina vs Napoli Italian Serie A game?

The Fiorentina vs Napoli game takes place on Sunday, September 20, 2026, kicking off at 6:30 AM ET / 3:30 AM PT.

Where is the Fiorentina vs Napoli game being played?

The game is being played at Artemio Franchi in Florence.

Where can I watch Fiorentina vs Napoli?

The game will be broadcast live on Movistar Liga de Campeones and Canal+ Deportes 2.

What are the probable lineups for Fiorentina vs Napoli?

Fiorentina's probable lineup features De Gea, Viery, Ranieri, Pongracic, Mario, Atta, Fagioli, Ndour, Njie, Pellegrino, and Mastantuono. Napoli is projected to start Milinkovic-Savic, Spinazzola, Marin, Rrahmani, Di Lorenzo, Gilmour, Lobotka, De Bruyne, Lang, Højlund, and Politano.

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